Building Blocks

<p>Applications Phenyl 2-Chloroethyl Ether (cas# 622-86-6) is a compound useful in organic synthesis.<br></p>

<p>Applications trans-3-Hexenedioic Acid is used as a starting material in the synthesis of Adipic Acid (A291590) which is primarily used in the synthesis of nylon.<br>References Kim, Y. et al.: Ind. Eng. Chem. Res., 51, 15801 (2012); Li, C., et al.: Electrochim. Acta, 56, 1529 (2010)<br></p>

<p>Applications Piperidin-4-one Ethylene Ketal is a derivative formed from the condensation of cyclohexanone.<br></p>

<p>Applications 3-MERCAPTO-4-METHYL-4H-1,2,4-TRIAZOLE (cas# 24854-43-1) is a useful research chemical.<br></p>

<p>Applications Ethyl Carbazate is used in the synthesis of P1 aryl heterocycle-based thrombin inhibitors. It can be also used to prepare diazenedicarboxamides as inhibitors of alanylalanine ligase.<br>References Young, M., et al.: J. Med. Chem., 47, 2995 (2004); Kovac, A., et al.: Bioorg. Med. Chem. Lett., 17, 2047 (2007)<br></p>

<p>Applications 2-Bromothiazole is a heterocyclic S compound to induce base-pair substitution and having mutagenic activity.<br>References Voogd, C.E., et al.: Mutation Research, Genetic Toxicology Testing, 118, 153 (1983),<br></p>

<p>Applications 2-Hydroxy-1-phenylpentane is an impurity of Prolintane (P756100) synthesis.<br>References Hucker, H.B. et al.: Experientia, 28, 430 (1972); Hollister, L.E. et al.: J. Clin. Pharmacol. J. New Drugs, 10, 103 (1970); Kuitunen, T. et al.: Meth. Find. Exp. Clin. Pharmacol., 6, 265 (1984):<br></p>

<p>Applications Phenylmalonic Acid Mono-5-indanyl Ester is an intermediate in the synthesis of Indanylcarbinicillin (S635000), an compound shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic.<br></p>

<p>Applications 3,4,5-TRIHYDROXYBENZALDEHYDE HYDRATE (cas# 207742-88-9) is a useful research chemical.<br></p>

<p>Applications 4,5-Dimethyl-o-phenylenediamine is used in biological processes as a substrate for CobT nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella typhimurium LT2.<br>References Trzebiatowski, J.R., et al.: J. Biol. Chem., 272, 17662 (1997); Johnson, M.G., et al., J. Biol. Chem., 267, 13302 (1992); Cheong, C., et al.: J. Biol. Chem., 277, 41120 (2002)<br></p>

<p>Applications Methoxyacetaldehyde Dimethyl Acetal is a reagent used in balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-1R inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zimmermann, K., et al.: Bioorg. Med. Chem. Lett., 18, 4075 (2008);<br></p>

<p>Applications 1-Propylpiperazine dihydrobromide (cas# 64262-23-3) is a useful research chemical.<br></p>

<p>Applications 2-Methoxy-4-aminobenzoic Acid (cas# 2486-80-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.<br>References Keul, H., et. al.: Macromol. S., 19, 1 (1971)<br></p>

<p>Applications 3-(Chloromethyl)pyridine Hydrochloride has been used as a reactant for the synthesis of (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-one derivatives as Polo-like kinase 4 (PLK4) inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laufer, R., et. al.: J. Med. Chem., 56, 6069 (2013)<br></p>

<p>Applications 2-Fluorobenzaldehyde is a compound that has inhibitory effects on the activity of mushroom tyrosinase, a copper-containing enzyme that is widely used in a number of applications such as direct protein-protein cross linking, and activating tyrosine residues in polypeptides for protein cross-linking to chitosan films.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Halaouli, S., et al.: J. Appl. Microbiol., 100, 219 (2006); Huang, X., et al.: J. Enzyme Inhib. Med. Chem., 21, 413 (2006); Sung-Yum, S., et al.: J. Agric. Food Chem., 51, 2837 (2003);<br></p>