Building Blocks

<p>Applications A precursor to 3-Methyl-2-butenyl-1-thiol which is very unstable. We will provide a detailed procedure for the preparation of the thiol from the thiolacetate with spectral data upon request.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications trans-Cyclohexane-1,4-diamine (cas# 2615-25-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N’-(4-Cyanobutyl)-N-(4-methoxybenzyl)-N’-methyl-N-2-pyridinyl-1,2-ethanediamine (cas# 109912-34-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Used in a novel process for preparing β-hydroxy-fatty acids which are useful as base material for lipids A, LB films, cosmetics, liquid crystals etc.<br>References Hanahan, D., et al.: J. Mol. Biol., 166, 557 (1983), Yang, S., et al.: Biotechnol. Bioeng., 43, 1124 (1994), Ramsay, J., et al.: Can. J. Microbiol., 41, 262 (1995), Rehm, B., et al.: Intl. J. Biol. Macromol., 25, 3 (1999),<br></p>

<p>Applications N-Boc-p-phenylenediamine is the boc protected compound of 1,4-Phenylenediamine (P319845). 1,4-Phenylenediamine is a hair dye component, paraphenylenediamine, as a contact allergen for treatment of inflammatory diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, K., et al.: J. Med., 13, 131 (1982), Baud, F., et al.: J. Toxicol. Med., 4, 279 (1984), Ashraf, W., et al.: Human Exp. Toxicol., 13, 167 (1994),<br></p>

<p>Applications 2-Nitro-4,5-methylenedioxybenzaldehyde (cas# 712-97-0) is a compound useful in organic synthesis.<br>References Kajihara, Y., et al.: Carb. Res., 331, 455 (2001)<br></p>

<p>Applications Triethyltin Bromide is used as an endocrine disrupting compound, inducing adipogenesis through RXR and PPARγ activation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Grun, F. et al.: Mol. Endocrinol., 20, 2141 (2006); Yano, K. et al.: J. Health Sci., 49, 195 (2003)<br></p>

<p>Applications 5-Nitroisoquinoline (cas# 607-32-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Methylamino-1,2-propanediol (cas# 40137-22-2) is a useful research chemical.<br></p>

<p>Applications 1,4-Bis(diphenylphosphino)butane is a catalyst precursor used in organic synthesis such as the preparation of phenanthrothiazoles.<br>References Shi, X. et al.: J. Org. Chem., 82, 3886 (2017);<br></p>

<p>Applications 6-Chloro-1-hexanol is used as a reagent in the synthesis of 3-(4-Chloro butyl)-1H-indole-5-carbonitrile; a key intermediate of the antidepressant drug Vilazodone (V265000).<br>References Anitha, N., et al.: Synthetic Commun., 44, 3563 (2014)<br></p>

<p>Applications 2-Bromobenzoic acid is a sterically hindered ortho-bromo compound that is used as a starting material to synthesize quinazolinones (e.g. 8-Hydroxy-2-methyl-4(3H)-quinazolinone [H948330]).<br>References Liu, X., et al.: Angew. Chem. Int. Edit., 121, 354 (2009); Lu, G., et al.: Tetrahedron Lett., 46, 4255 (2005)<br></p>

<p>Applications Used in the preparation of phenyloxadiazolyl pyridines as immunomodulating agents.<br>References Iwakubo, M., et al.: Bioorg. Med. Chem., 15, 350 (2007), Schaafsma, D., et al.: Eur. J. Pharmacol., 585, 398 (2008),<br></p>

<p>Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boettecher, B. &amp; Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)<br></p>

<p>Applications DI-Tert-Butyl Hydrazodicarboxylate (cas# 16466-61-8) is a useful research chemical.<br></p>

<p>Applications Used for preparation of [[(triazolylmethyl)pyridyl]phenyl]tetrazoles and related compounds as cardiovascular agents.<br>References Behforouz, M., et al.: J. Med. Chem., 46, 5773 (2003), Behforouz, M., et al.: Bioorg. Med. Chem., 15, 495 (2007),<br></p>

<p>Applications 5-Hydroxy-2-oxo-2,3-dihydro-1H-[1]benzazephe-4-carboxylic Acid Ethyl Ester (cas# 108993-98-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl β-Resorcylate, is a building block used for the synthesis of different pharmaceutical compounds. It can be used for the synthesis of series of CCR1 antagonists based upon spirocyclic compounds.<br>References Hossain, N., et al.: Bioorg. Med. Chem. Lett., 23, 3500 (2013);<br></p>