Building Blocks

<p>Applications 4-(4'-Bromophenyl)-4-hydroxypiperidine is a metabolite of bromoperidol.<br>References Wong, F. A., et al.: Drug Metab. Dispos., 11, 301 (1983); Lyles-Eggleston, M. D., et al.: Med. Chem. Res., 9, 686 (1999); Sato, S., et al.: Pharmacol. Toxicol., 86, 145 (2000)<br></p>

<p>Applications 2,4,6-Collidine is an reagent used for various synthetic preparations such as the synthesis of methylated pyridines by three-componet catalytic condensation of acetylene, acetone and ammonia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pertel, S.S., et al.: Carbohydrate. Rsch., 356, 172 (2012); Kung, A. C., et al.: J. Org. Chem., 70, 3127 (2005);<br></p>

<p>Applications 1,4-Cyclohexanediol is used as a reagent in the development of noviomimetics as C-terminal Hsp90 inhibitors.<br>References Anyika, M., et al.: ACS Med. Chem. Lett., 7, 67 (2016)<br></p>

<p>Applications p-Toluenesulfonyl Isocyanate has been used to react with a prepolymer with the OH-functionality.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Muenker, A.H., Hudson, B.E.: J. Macromol. Sci. Chem., 3, 1465 (1969)<br></p>

<p>Applications 1-Bromohexadecane is used in the preparation of soluble carbon nano-onions by covalent functionalization with hexadecyl chains. It is also used to synthesize [2-(methacryloyloxy)ethyl]dimethylhexadecylammonium bromide monomer, required for the synthesis of novel methacrylate based adsorbents.<br>References Molina-Ontoria, A., et al.: Chem. Comm., 49, 2406 (2013); Shu, M., et al.: Analyst, 137, 2143 (2012)<br></p>

<p>Applications Benzoic Anhydride is the more active analogue of benzoic acid formed via dehydration. Benzoic Anhydride is used in the synthesis of a wide range of organic compounds including some dyes. Benzoic Anhydride is also used as an arylation agent in the Heck reaction.<br>References Lewis, D.M. et al.: J. Soc. Dyes Col., 99, 354 (1983); Shmidt, A.F. et al.: Kin. Catal., 41, 743 (2000);<br></p>

<p>Applications Trimethylboroxin is used in a diverse array of areas, including as a polymerization additive. Trimethylboroxin is also used in the preparation of CBS catalysts for asymmetric reductions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gilmore, N., et al.: Tetrahedron Asy., 14, 2115 (2003); Najera, C., et al.: Adv. Synth. Catal., 346, 1798 (2004);<br></p>

<p>Applications N,N-DIMETHYLFORMAMIDE DINEOPENTYL ACETAL (cas# 4909-78-8) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications A phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori, et al.: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Stability Moisture sensitive<br>Applications Octanoyl Chloride is commonly used as an acylating agent for a variety of compounds such as sugars (e.g. Sucrose [S697000]), aromatic compounds (e.g. Anisole [A673900]), and monoglycerides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bass, D., et al.: J. Biol. Chem., 263, 19610 (1988); Ganong, B., et al.: P. Natl. Acad. Sci. USA, 83, 1184 (1986); Shih, P., et al.: Catal. Today, 93-95, 365 (2004); Thévenet, S., et al.: J. Carbohyd. Chem., 16, 691 (1997)<br></p>

<p>Applications 1-Heptyne can be used for cycloisomerization of alkynyl imines and alkynylation of oxiranes.<br>References Kel’in, A. V., et al.: J. Am. Chem. Soc. 123, 2074 (2001); Yamaguichi, M., et al.: Tetrahedron Lett. 24, 391 (1983)<br></p>

<p>Applications 2-Amino-5-bromo-4,6-dimethylpyridine (cas# 89856-44-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Reagent used in the preparation of many pharmaceutically active compounds such as antiulcer agents, antitumor agents, antibiotics and anxiolytics.<br>References Colabufo, N., et al.: J. Med. Chem., 51, 7602 (2008), Manfroni, G., et al.: Bioorg. Med. Chem. Lett., 19, 714 (2009),<br></p>

<p>Applications 2-Bromopropionic Acid is a versatile reactant used in emulsion polymerization in the preparation of reversible addition-fragmentation chain transfer (RAFT) agent.<br>References Ferguson, C., et al.: Macromolecules, 35, 9243 (2002); Ferguson, C., et al.: Macromolecules, 38, 2191 (2005);<br></p>

<p>Applications 3-(Chloromethyl)pyridine Hydrochloride has been used as a reactant for the synthesis of (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-one derivatives as Polo-like kinase 4 (PLK4) inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laufer, R., et. al.: J. Med. Chem., 56, 6069 (2013)<br></p>

<p>Applications 2-Bromoethyl-d4-amine HBr (CAS# 918633-70-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-(Hydroxymethyl)-4-nitrophenol (cas# 60463-12-9) is a useful research chemical.<br></p>

<p>Applications 2,4,6-Trichlorobenzoyl Chloride, can be used for the preparation of large-ring lactones in high yields. It is used for the syntheisis of cytotoxic marine natural product Amphidinolide X and Jasplakinolide (J210700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fieser, M. Reagents for Organic Synthesis New York 16, 353, (1992); Lepage, O., et al.: J. Amer. Chem. Scoi., 126 (49), 15970<br></p>