Building Blocks

<p>Applications Ethyl 3-benzoylacrylate is an impurity of Enalapril (E555250), an antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor.<br>References Gross, M., et al.: J. Pharmacol. Exp. Ther., 216, 552 (1980), Gomez, H.J., et al.: J. Cardiovasc. Pharmacol., 15, Suppl. 3, S26-S29, (1990), MacFadyen, J., et al.: Clin. Pharmacokinet., 25, 274 (1993), Malini, P.L.: Adv. Ther., 10, 253 (1993),<br></p>

<p>Stability Moisture Sensitive<br>Applications Chloromethoxysulfonyl Chloride is a useful intermediate for organic synthesis. Chloromethoxysulfonyl Chloride is a useful reagent for the preparation of HIV-attachment inhibitor BMS-663068, and in the synthesis of water soluble benzimidazole derivatives useful for treatment of fasciolosis.<br>References Fox, R. J., et al.; Org. Process Res. Dev., 21, 1095 (2017); Flores-Ramos, M., et al.: Bioorg. Med. Chem. Lett., 24, 5814 (2014); Zheng, B., et al.: Org. Process Res. Dev., 16, 1827 (2012)<br></p>

<p>Applications 9-Oxo-9H-fluorene-4-carboxylic acid (cas# 6223-83-2) is a useful research chemical.<br></p>

<p>Applications Myristoyl Chloride is a building block that has been used to form esters on rubber wood. Esterification reduces crystalinity of wood and reduces light0induced color changes (phot-yellowing ) at wood surfaces. Myristoyl Chloride has also been used in the modification of isophalate-PEG copolymers to make amphiphilic copolymers as nanocarriers for drug delivery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salla, J., et. al.: J. Wood Chem. Tech. , 32, 121 (2012); Gupta, B., et. al.: J. Macromol. Sci. Pure, 48, 1009 (2011)<br></p>

<p>Applications 3-​Chloroiodobenzene is used in the synthesis of is a common organic reagent used i the synthesis of a prostacyclin agonist actin in the treatment of pulmonary hypertension.<br>References Tran, T. et al.: J. Med. Chem., 60, 913 (2017);<br></p>

<p>Applications A precursor to 3-Methyl-2-butenyl-1-thiol which is very unstable. We will provide a detailed procedure for the preparation of the thiol from the thiolacetate with spectral data upon request.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Chloro-2-fluoroaniline is a compound used in the synthesis of 4-Chloro-2-fluoro-3-iodobenzenamine (1000590-87-3).<br></p>

<p>Applications 4-Bromophenylacetic Acid (cas# 1878-68-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Methylamino-1,2-propanediol (cas# 40137-22-2) is a useful research chemical.<br></p>

<p>Applications An intermediate in the preparation of a potential inhibitor of GAR Tfase.<br>References Cheng, H. et al.: Bioorg. Med. Chem., 13, 3593 (2005)<br></p>

<p>Applications 5-Oxo-5-phenylvaleric Acid is used in various synthetic preparations. It is used in the synthesis of fulleroid and methanofullerene derivatives. Also used in tertiary amino urea-catalyzed enantioselective iodolactonization.<br>References Hummelen, J., et al.: J. Org. Chem., 60, 532 (1995); Veitch, G., Jacobsen, E.: Angew. Chem. Int. Ed., 49, 7332 (2010);<br></p>

<p>Applications 1-​Bromododecane (n-Lauryl Bromide) is a reagent used in the synthesis of porous organic polymers.<br>References Zhao, Y. et al.: ACS Macro. Lett., 7, 300 (2018);<br></p>

<p>Applications 2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.<br>References Liu, J., et al.: Synthesis., 45, 943 (2013); Rambabu, D., et al.: Bioorg. Med. Chem. Lett., 23, 1351 (2013);<br></p>

<p>Applications Intermediate in the preparation of Ertapenem (E635000).<br></p>

<p>Applications 2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid-d3 (cas# 1346604-53-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl-d5 2-Methylbutyrate is the labeled analogue of Ethyl 2-Methylbutyrate (E923200), an ester that has a sweet, apple-like aroma. Ethyl 2-methylbutyrate is naturally found in apples, cherries and orange juice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cho, I., et al.: J. Agr. Food Chem., 54, 6332 (2006); Mattheis, J., et al.: J. Agr. Food Chem., 45, 212 (1997); Moshonas, M. &amp; Shaw, P.: J. Agr. Food Chem., 35, 161 (1987); Willaert, G., et al.: J. Agr. Food Chem., 31, 809 (1983)<br></p>

<p>Applications 1-Dodecyne (CAS# 765-03-7) is a useful research chemical compound.<br></p>

<p>Applications 4-Chloropyridine-2-carboxamide, is a versatile building block used in synthesis of various chemical compounds.<br></p>