Building Blocks

<p>Stability Moisture sensitive<br>Applications Octanoyl Chloride is commonly used as an acylating agent for a variety of compounds such as sugars (e.g. Sucrose [S697000]), aromatic compounds (e.g. Anisole [A673900]), and monoglycerides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bass, D., et al.: J. Biol. Chem., 263, 19610 (1988); Ganong, B., et al.: P. Natl. Acad. Sci. USA, 83, 1184 (1986); Shih, P., et al.: Catal. Today, 93-95, 365 (2004); Thévenet, S., et al.: J. Carbohyd. Chem., 16, 691 (1997)<br></p>

<p>Applications 3-Chlorobenzoyl Chloride is used in the synthesis of isoquinoline derivatives as potent CRTH2 antagonists in treatment of allergies. Also used in the synthesis of anticancer 2-phenzainamine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nishikawa-Shimono, R. et al.: Bioorg. Med. Chem., 21, 7674 (2013); Gao, X. et al.: Eur. J. Med. CHem., 69, 1 (2013);<br></p>

<p>Applications 3-Methyl-1,5-pentanediol is a reagent used in the preparation of lactones from diols using molecular oxygen oxidant and hydrotalcite-supported gold nanoparticles catalysts under mild conditions.<br>References Mitsudome, T., et al.: Green Chem., 11, 793 (2009)<br></p>

<p>Applications Methyl 3-(4-chlorophenyl)-3-oxopropanoate (cas# 22027-53-8) is a useful research chemical.<br></p>

<p>Applications o-Isopropylaniline was used in the synthesis of a colorless amine-coordinated zinc complex.<br>References Li, D., et al.: Org. Biomol. Chem., 8, 1816 (2010)<br></p>

<p>Applications 2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.<br>References Liu, J., et al.: Synthesis., 45, 943 (2013); Rambabu, D., et al.: Bioorg. Med. Chem. Lett., 23, 1351 (2013);<br></p>

<p>Applications 2-Amino-5-bromo-4,6-dimethylpyridine (cas# 89856-44-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-​Amino-​6-​methylpyridine is a reagent used in the identification of selective inhibitor for phosphatidylinositol 3-kinase (PI3Kα).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, M. S., et al.: Bioorg. Med. Chem., 25, 1481-1486 (2017);<br></p>

<p>Stability Air Sensitive, Stench<br>Applications Allyl Mercaptan (&gt;75%) can be used to treat Alzheimer's, stroke, cardiovascular and other amyloid related diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Postrel, R., U.S. Pat. Appl. Publ. US 20200215009 A1, 10, (2020);<br></p>

<p>Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boettecher, B. &amp; Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)<br></p>

<p>Applications 4-Chlorobutanoic acid methyl ester is used as a precursor chemical for projects such as vapor deposition for attaching ionic liquid to oxide surfaces1 and the synthesis of new thiopyran-​based heterocyclic systems2.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Xu, W., et al.: Angew. Chem. Int Ed., 56, 9072-9076. (2017)2. Palchykov, V.A., and al.: New J. Chem., 42, 1403 - 1412 (2018)<br></p>

<p>Applications 4-(Chloromethyl)benzoyl Chloride is used in the synthetic preparation of various compounds and pharmaceuticals. 4-(Chloromethyl)benzoyl Chloride was used in the synthesis of several imidazo[2,1-b]thiazoles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bratulescu, G., et al.: Asian. J. Chem., 24, 350 (2012);<br></p>

<p>Applications A useful synthetic intermediate.<br></p>