Building Blocks

<p>Applications 1,4-Cyclohexanediol is used as a reagent in the development of noviomimetics as C-terminal Hsp90 inhibitors.<br>References Anyika, M., et al.: ACS Med. Chem. Lett., 7, 67 (2016)<br></p>

<p>Applications 6-Hydroxy-5-iodo-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid γ-Lactone is an intermediate in the synthesis of neuraminidase inhibitors.<br>References Kunstmann, M.P., et al.: J. Am. Chem. Soc., 84, 4115 (1962);<br></p>

<p>Stability Moisture sensitive<br>Applications Octanoyl Chloride is commonly used as an acylating agent for a variety of compounds such as sugars (e.g. Sucrose [S697000]), aromatic compounds (e.g. Anisole [A673900]), and monoglycerides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bass, D., et al.: J. Biol. Chem., 263, 19610 (1988); Ganong, B., et al.: P. Natl. Acad. Sci. USA, 83, 1184 (1986); Shih, P., et al.: Catal. Today, 93-95, 365 (2004); Thévenet, S., et al.: J. Carbohyd. Chem., 16, 691 (1997)<br></p>

<p>Stability Moisture Sensitive<br>Applications 10-Bromodecanol can be used to synthesize rotaxane dendrimers. It can also be used to synthesize J2326, a molecule that induces neurite outgrowth in neuronal cells.<br>References Wei, W., et al.: Proc. Natl. Acad. Sci. USA 112, 5597 (2015); Chang, P., et al.: Neuropharmacology 92, 146 (2015)<br></p>

<p>Applications 4-methylthiazol-2-amine (cas# 1603-91-4) is a useful research chemical.<br></p>

<p>Applications 1-BROMOEICOSANE (cas# 4276-49-7) is a useful research chemical.<br></p>

<p>Applications 1-Bromo-4-phenylbutane<br></p>

<p>Applications 3-Bromopropionitrile acts as a reagent in the preparation of bisindole maleimide derivative useful as α-glucosidase inhibitors for the treatment of diabetesis. Also used in the study of the structure activity relations between alkyl nucleophilic chemicals causing duodenal ulcer and adrenocortical necrosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Szabo, S., et al.: J. Pharm. Exp. Ther., 223, 68 (1982); Zhu, W., et al.: Faming Zhuanli Shenqing (2016); CN 106146487 A 20161123;<br></p>

<p>Applications trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine is a useful research chemical for organic synthesis and other chemical processes.<br>References Bollenbach, M., et al.: Chem. Eur. J., 23, 13676 (2017); Thaisrivongs, D. A., et al.: Org. Lett., 18, 5780 (2016)<br></p>

<p>Applications 6-Chloro-1-hexanol is used as a reagent in the synthesis of 3-(4-Chloro butyl)-1H-indole-5-carbonitrile; a key intermediate of the antidepressant drug Vilazodone (V265000).<br>References Anitha, N., et al.: Synthetic Commun., 44, 3563 (2014)<br></p>

<p>Applications 3-MERCAPTO-4-METHYL-4H-1,2,4-TRIAZOLE (cas# 24854-43-1) is a useful research chemical.<br></p>

<p>Stability Air Sensitive, Stench<br>Applications Allyl Mercaptan (&gt;75%) can be used to treat Alzheimer's, stroke, cardiovascular and other amyloid related diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Postrel, R., U.S. Pat. Appl. Publ. US 20200215009 A1, 10, (2020);<br></p>

<p>Applications Methyl 4-Methoxyphenylacetate (cas# 23786-14-3) is a useful research chemical.<br></p>

<p>Applications 4,5-Dimethyl-o-phenylenediamine is used in biological processes as a substrate for CobT nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella typhimurium LT2.<br>References Trzebiatowski, J.R., et al.: J. Biol. Chem., 272, 17662 (1997); Johnson, M.G., et al., J. Biol. Chem., 267, 13302 (1992); Cheong, C., et al.: J. Biol. Chem., 277, 41120 (2002)<br></p>

<p>Applications Possess activity against positive phototaxis of Chlamydomonas cells.A fundamental starting material for organic synthesis.<br>References Evans, S., et al.: Chem. Biol. Drug. Des., 75, 333 (2010), Rajabi, L., et al.: Lett Appl Microbiol., 40, 212 (2005),<br></p>

<p>Applications Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level.<br>References Yin, L., et al.: PLoS One., 7, 48048 (2012); Rodriguez, J.D.,e t al.: Chem. Biochem. Engin. Quart., 20, 173 (2006);<br></p>

<p>Applications 3-Hydroxypropionitrile (cas# 109-78-4) is a compound useful in organic synthesis.<br></p>