Building Blocks

<p>Applications 2-Amino-4,6-dimethylpyrimidine is a bioactive compound.<br>References Phan, D. C., et al.: Hoa Hoc Va Cong Nghiep Hoa Chat, 8, 30 (2001); Shen, Z., et al.: Yingyong Huagong, 37, 721 (2008)<br></p>

<p>Applications 2-Hydroxyisobutyric Acid is used as a reagent in the preparation of fully functionalized tetronic acids. Also used in the synthesis of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides which display anticonvulsant activity.<br>References Prousis, K., et al.: Tetrahedron, 71, 8637 (2015); Pastore, V., et al.: Bioorgan. Med. Chem., 21, 841 (2013);<br></p>

<p>Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.<br>References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)<br></p>

<p>Applications 4-Aminobenzamide (cas# 2835-68-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 3-Amino-3-azabicyclo[3,3,0]octane is used as a reactant in the synthesis of Gliclazide (G409875), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972); Holmes, B., et al.: Drugs, 27, 301 (1984)<br></p>

<p>Applications 1-AMINO-2-METHYLNAPHTHALENE (cas# 2246-44-8) is a useful research chemical.<br></p>

<p>Applications Alizarin is used widely as a prominent red dye for textile facbrics. Alizarin red is now used in biochemical assay to determine quantitatively by colorimetry, the presence of calcific deposition by cells of the osteogenic lineage. Alzarine derivatives was evaluated as new inhibitors of the HIV-1 reverse transcriptase associated DNA polymerase and RNase H. Alizarin was also shown to inhibit proliferation, tumor growth and suppress tumorigenesis in human osteosarcoma and breast cancer cell representative for bone metastasis. Dyes and metabolites.<br>References Yuan, H.S., et al.: Mycol., 3, 100 (2012); Esposito, F. et al.: FEBS. J., 278, 1444 (2011); Fotia, Caterina, J. Orthop. Rsch. 30, 1486 (2012);<br></p>

<p>Applications 2-Hydroxybenzeneethanol can be used to synthesize cyclic products and organoaluminim oligomers. Inelastic electron tunnelling spectra of 2-hydroxyphenethyl alcohol adsorbed on thin-film aluminium and magnesium oxide has been investigated.<br>References Ziemkowska, W., et al.: Main Group Met. Chem., 21, 105, (1998); Brown, N., et al., Spectrochim. Acta A, 48, 939 (1992)<br></p>

<p>Applications L-Alanyl-L-proline is a dipeptide that contains a sterically constrained proline, a well-known turn inducer in proteins.<br>References Moriuchi, T., et al.: J. Organomet. Chem., 589, 50 (1999)<br></p>

<p>Applications Tiglic acid is the stable isomer of angelic acid. Tiglic acid was found as glyceride in croton oil, as butyl ester in the oil of the Roman camomile, and as geranyl tiglate in oil of geranium. Tiglic acid is formed during the charcoaling of maple wood.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bueding, et al.: J. Biol. Chem., 202, 505 (1953),<br></p>

<p>Applications 10-Hydroxybenzo[h]quinoline-7-sulfonate is used as a fluorescence method for the determination of beryllium and beryllium oxide particles.<br>References Agrawal, A., et. al.: J. ASTM Int., 8, 10 (2011); Zheng, Y., et. al.: Talanta, 85, 638 (2011)<br></p>

<p>Applications 4-Acetylpyridine is a acetylated pyridine used in the preparation of nitrogen containing bicyclic heterocycles and other organic compounds. 4-Acetylpyridine is also present in mainstream cigarette smoke.<br>References Kulshreshtha, N.P. et al.: J. Chrom. A, 985, 303 (2003); Scian, M. et al.: Inhal. Toxicol., 21, 1040 (2009);<br></p>

<p>Stability Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive<br>Applications N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4).<br>References (1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006) (2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)<br></p>