Building Blocks

<p>Fmoc-D-glu-OtBu is an amide that can be used as a screening reagent for the detection of carbohydrate and periplasmic compounds. It has been shown to inhibit hepatitis in humans, which may be due to its ability to bind with muramyl dipeptide. Fmoc-D-glu-OtBu has also been shown to synergize with other vaccines, such as tetanus and escherichia coli surface antigen.</p>

<p>5-Bromoisothiazole is a conformationally constrained isoform of isothiazole. It has significant antifungal activity and binds to a number of kinases. 5-Bromoisothiazole has been shown to have chemokine inhibitory effects in human breast carcinoma cells. This molecule also inhibits the production of cyclooxygenase-2, and may be used to treat inflammatory diseases such as rheumatoid arthritis. 5-Bromoisothiazole also inhibits the synthesis of nitric oxide by inhibiting the enzyme nitrosylating reductase, which is involved in the conversion of nitrate to nitrite. The biological function of this molecule is not yet well understood, but it may play a role in cellular metabolism or cell signaling.</p>

<p>Cyclohexylmethanethiol is a reactive chemical that is a colorless liquid with a strong odor. It is an organic compound belonging to the group of polybasic, hydroxamic acids and has been found to be an antimicrobial agent. Cyclohexylmethanethiol reacts with the hydroxyl groups on the surface of bacteria and damages the cell wall by disrupting the cross-linking of peptidoglycan. This reaction product inhibits bacterial growth by binding to proteins in the cell membrane, which prevents essential molecules from entering or exiting the cell. Cyclohexylmethanethiol also reacts with alkylthio groups on proteins in bacterial cells, which alters their function and leads to protein denaturation.</p>

<p>Versatile small molecule scaffold</p>

<p>Purity min. 95%</p>

<p>2-Phenylethanimidamide hydrochloride is a chemical compound that is used as an insecticide and acaricide. It is a derivative of benzonitrile, which contains a chlorine atom. 2-Phenylethanimidamide hydrochloride is typically sprayed on plants to control pests such as mites, aphids, and beetles. This product can be mixed with other chemicals that help it stay on the plant for longer periods of time. The use of 2-phenylethanimidamide hydrochloride does not pose any health risks to humans or animals when use according to the directions on the label.</p>

<p>Sphingolipid; cell membrane component; anti-inflammatory agent</p>

<p>Methyl 2-naphthoate is a chinese herb that has been used as a traditional medicine to treat inflammatory diseases. Methyl 2-naphthoate contains a carbonyl group, which is an important part of the molecule. The 13C NMR spectroscopy and X-ray crystal structures reveal the presence of a hydrogen bond between the carbonyl group and water molecule. The kinetic data demonstrate that methyl 2-naphthoate has significant cytotoxicity in vitro. These results were confirmed by in vivo experiments using mice with myeloma cells. Moreover, methyl 2-naphthoate was found to significantly suppress pro-inflammatory factors such as TNF-α and IL-1β.<br>Methyl 2-naphthoate is an analytical method for detecting carboxylic acid derivatives in organic solvents because it reacts with thiourea to produce colorless crystals of methyl naphthylamide.</p>

<p>AdipoRon is a high-quality, versatile building block that can be used in the synthesis of complex molecules. It is a reagent and speciality chemical with applications in research and development. AdipoRon reacts with other chemicals to form new compounds, which are useful as scaffolds for the synthesis of pharmaceuticals or fine chemicals.</p>

<p>Caffeic acid is naturally produced by the metabolism of plants and fungi. Caffeic acid has an antioxidant activity that can be higher than tocopherol in oil-in-water emulsions. Caffeic acid has proven antimicrobial activity against Staphylococcus aureus. In mice, caffeic acid inhibits the enzyme 5-lipoxygenase thus inhibititing the biosynthesis of the inflammatory mediators leukotrienes.</p>

<p>Furan-2-sulfonamide is a quinoline derivative that prevents HIV from entering the host cell. It inhibits the activation of toll-like receptor (TLR) by blocking the binding of TLR ligands to their receptors. Furan-2-sulfonamide has been shown to be effective in reducing inflammation in inflammatory bowel disease, inflammatory diseases, and pancreatitis. Furan-2-sulfonamide may also have anti-cancer effects by inhibiting the growth of cancer cells and inducing apoptosis. Furan-2-sulfonamide can be used as a part of pharmaceutical preparations for treating symptoms such as pain, nausea, vomiting, or diarrhea. This drug also inhibits matrix metalloproteinases (MMP), which are enzymes that break down collagen in the body. The inhibition of MMP leads to decreased breakdown of skin or bladder tissue and increased healing time in patients with these conditions.</p>

<p>3-Bromoadamantane-1-carboxylic acid is a potent inhibitor of sphingosine kinase. It is a synthetic compound that was developed to inhibit the activity of sphingosine kinase and thus reduce the levels of sphingosines in cells. 3-Bromoadamantane-1-carboxylic acid has been shown to be effective against multikinases, including caspases and protein kinases. The drug is also able to inhibit tumor growth in animals. The mechanism by which 3-bromoadamantane-1-carboxylic acid inhibits tumor growth is unknown but may involve its ability to bind to the ATP binding site on the enzyme complex or its ability to form a noncompetitive inhibitor with ATP.</p>

<p>Benzophenone imine is a metabolite that is produced during the metabolism of benzophenones. It was first synthesized in 1887 by the reaction of copper chloride and benzene-1,2-diamine. The reaction solution was purified by fractional crystallization to give crystals of benzophenone imine hydrochloride (benzophenamine) as a white solid. The x-ray crystal structures were determined for two different forms, one with the 5-hydroxy group in the para position relative to the imine and one with it in the meta position. Benzophenone imine is an amide that has been shown to bind to 5-HT2 receptors, which are found primarily on neurons in the central nervous system. This binding leads to an increase in serotonin levels and an inhibition of glutamate release from nerve terminals. This inhibition can lead to infectious diseases such as herpes zoster.</p>

<p>1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin (BMT) is a synthetic analog of oxytocin. Oxytocin is a hormone that is produced in the hypothalamus and released by the pituitary gland to stimulate uterine contractions and milk letdown in mammals. 1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin has been shown to bind to the oxytocin receptor and stimulate the release of insulin, which may be useful for treating type 2 diabetes. BMT also stimulates epidermal growth factor (EGF) production and induces skin cell growth. It has been used as an animal health drug for stimulating appetite, increasing weight gain, reducing inflammation, and lowering blood pressure.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chlorophenyl[3-(trifluoromethyl)phenyl]methanone is a chemical compound that can be used as a reaction component or a reagent. It is often used as a building block in organic synthesis, due to its high quality and versatility. 4-Chlorophenyl[3-(trifluoromethyl)phenyl]methanone is soluble in organic solvents and has been shown to have no significant toxicity. This chemical is also useful for the production of complex compounds with various applications, such as pharmaceuticals, agrochemicals, and dyes.</p>

<p>2,3-Dichloro-N-[2-({2-[(2,3-dichlorophenyl)amino]ethyl}amino)ethyl]aniline is a chemical compound that is used as a building block in the synthesis of other chemicals. It is also used as a reagent, speciality chemical and research chemical. This product has many uses in the field of organic chemistry, such as use as an intermediate in organic reactions or as a scaffold for complex compounds. 2,3-Dichloro-N-[2-({2-[(2,3-dichlorophenyl)amino]ethyl}amino)ethyl]aniline has high quality and can be used to synthesize many different products.</p>

<p>Indole-4-carboxylic acid methyl ester is a fine chemical that is used as a building block in the synthesis of complex compounds. It can be used as a reagent, speciality chemical, or intermediate, and it has versatile applications in the synthesis of pharmaceuticals and dyes. Indole-4-carboxylic acid methyl ester has been shown to react with alcohols to form ketones, which are useful scaffolds for organic chemistry. It can also be used as a reaction component for the synthesis of other compounds.</p>

<p>2,2'-Bipyridine-5,5'-dicarboxylic acid is an algal metabolite that has been shown to have a glucose sensor function. It is synthesized by Chlorella and other green algae in response to light and high concentrations of glucose. This compound can be used as a linker for the immobilization of fluorescent probes or luminescent probes. It also has a catalytic subunit that can be used in oxidation reactions at low temperatures with chloride as the oxidant. 2,2'-Bipyridine-5,5'-dicarboxylic acid is chemically stable and does not react with chloride or ligands. It can also be used as an oxidation catalyst for reactions at high temperatures.</p>

<p>5-Bromo-2,4-dichloropyrimidine is an aryl halide compound that is synthesized from 2,4-dichloropyrimidine and bromine. It has been shown to have inhibitory activities against cancer cells in vitro. 5-Bromo-2,4-dichloropyrimidine is used in the synthesis of the drug palbociclib (also known as PLX4720), which prevents mitotic progression by binding to the mitotic checkpoint protein (e.g., cyclin B). The reaction yield for this compound is low and its absorption enhancer properties are not well understood. 5-Bromo-2,4-dichloropyrimidine has also been used in conjunction with crotonic acid as a potential anticancer agent.</p>