Building Blocks

<p>Impurity Diacerein Impurity C<br>Stability Hygroscopic<br>Applications Found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves.A potential antioxidant resource: endophytic fungi from medicinal plants . Diacerein Impurity C<br>References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980), Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982), Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983),<br></p>

<p>Applications Methylenebis(phosphonic Dichloride) is used as a reagent in synthesis of several organic compounds including that of nucleoside 5'-methylenebis(phosphonate)s and bisphosphonated glycopeptide prodrugs for the treatment of osteomyelitis.<br> E0<br>References Kalek, M., et al.: Tetrahedron Lett., 46, 2417 (2005); Tanaka, K., et al.: Bioorg. Med. Chem. Lett., 20, 1355 (2010);<br></p>

<p>Applications Labeled D-Ribitol, which is used in the preparation of L-ribose and and arabinose. it is also a diagnostic tool for identifying human bladder cancer (HBC) through noninvasive urinary metabonomics.<br>References Pasikanti, K. et al.: J . Proteo. Res., 9, 2988 (2010); Ahmed, Z. et al.: J. Biosci. Bioeng., 88, 444 (1999);<br></p>

<p>Applications 3-propoxyaniline (cas# 4469-79-8) is a useful research chemical.<br></p>

<p>Applications L-Selenomethionine promotes cell cycle progression and is known to elevate the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase, and glutathione peroxidase. It has also been shown to selectively induce apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: J. Nutr., 132, 674 (2002); Sayed, W., et al.: Toxicol. In Vitro, 21, 157 (2007); Jornot, L., et al.: Biochem. J., 306, 581 (1995); Stewart, J., et al.: Nutr. Cancer, 60, 826 (2008)<br></p>

<p>Stability Moisture Sensitive<br>Applications Dimethyl chlorothiophosphate is an organophosphorus reagent that is used to synthesize phosphorus analogues of γ-aminobutyric acid, compounds that exhibit anticonvulsant properties. Dimethyl chlorothiophosphate is also used as a reagent to synthesize Parathion (P192220), a widely used pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cates, L., et al.: J. Med. Chem., 27, 654 (1984); DeBruin, K. &amp; Boros, E.: J. Org. Chem., 55, 609 (1990); Hall, S.: J. Am. Chem. Soci., 72, 2768 (1950); Kotronarou, A. &amp; Hoffmann, M.: Env. Sci. Tech., 26, 1460 (1992)<br></p>

<p>Applications 3-Fluoro-4-methoxycarbonylphenylboronic acid, pinacol ester is a useful intermediate for organic synthesis and other chemical transformations.<br>References Zhao, F., et al.: Eur. J. Med. Chem., 134, 147 (2017); Zhao, F., et al.: Bioorg. Med. Chem., 24, 4281 (2016)<br></p>

<p>Stability Hygroscopic<br>Applications Biogenic polyamine formed from spermidine and occurring in almost all tissues. Essential for both normal and neoplastic tissue growth. Involved in the modulation of calcium-dependent immune processes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Israel, et al.: J. Med. Chem., 7, 710 (1964), Janne, J., et al.: Biochim. Biophys. Acta, 473, 241 (1978). Theoharides, T.C., et al.: Life Sci., 27, 703 (1980), Horn, Y., et al.: Cancer Res., 42, 3248 (1982),<br></p>

<p>Applications Methyl 3-Hydroxybenzoate (cas# 19438-10-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-chloro-3-hydrazinylpyrazine (cas# 63286-28-2) is a useful research chemical.<br></p>

<p>Applications Benzotriazole-5-carboxylic acid (cas# 23814-12-2) is a useful research chemical.<br></p>

<p>Applications Temsavir is a Fostemsavir (CAS# 864953-29-7) intermediate and an antiviral agent. It is an HIV-1 attachment inhibitor.<br>References Landry, I., et al.: Antimicrob. Agents Chemother., 60, 2782-2789 (2016);<br></p>

<p>Applications 2,2':6',2''-Terpyridine (cas# 1148-79-4) is a useful research chemical.<br></p>

<p>Applications A metabolite of aldehydes.<br>References Shiobara, Y., et al.: Xenobiotica, 9, 157 (1979),<br></p>