Building Blocks

<p>Applications Tetrahydro-5-methyl-2-furanol is an intermediate in synthesizing 2,3-Dihydro-2-methylfuran (D447355), which is a general reagent used in next generation of biofuels. Dihydrofuranyl derivative.<br>References Simmie, J. et al.: J. Phys Chem., 116, 4528 (2012);<br></p>

<p>Applications Ethyl Diazoacetate is used in the synthesis of Arteludovicinolide A as well as pyrimidoazepine analogs as seritonin 5-HT2A/C receptor ligands for treatment of obesity. This compound contains solvent for added stability.<br> E0<br>References Yang, H. et al.: Eur. J. Med. Chem., 63, 558 (2013); Kreuzer, A. et al.: Org. Lett., 15, 3420 (2013);<br></p>

<p>Applications 2,7-Dimethylanthraquinone (cas# 3286-01-9) is a compound useful in organic synthesis.<br>References Kuo, D., et al.: J. Pharm. Pharmacol., 52, 839 (2000), Zagotto, G., et al.: Bioorg. Med. Chem., 16, 354 (2008),<br></p>

<p>Applications Mono-tert-butyl Succinate is a reagent used for the synthesis of fluorinated β2- and β3-amino acids, an inhibitor of α-chymotrypsin.<br>References Peddie, V., et al.: Synthesis, 1845-1859 (2010);<br></p>

<p>Applications Befunolol is a β-adrenergic blocker with an intrinsic sympathomimetic action. But it can work as a β-adrenergic partial agonist in isolated organs.<br>References Nakano, J., et al.: Chem. Pharm. Bull., 36, 1399 (1988); Takayanagi, I., et al.: Gen. Pharmacol., 20, 417 (1989); Koike, K., et al.: Gen. Pharmacol., 25, 1477 (1994)<br></p>

<p>Applications 2-ethylbenzamide (cas# 67832-97-7) is a useful research chemical.<br></p>

<p>Applications Used in the synthesis of selective β-adrenergic blocker Metoprolol.<br>References Su, W., et al.: J. Chem. Res., 6, 414 (2004),<br></p>

<p>Applications Chloropropanols have mutagenic and carcinogenic properties. The 3-monochloropropanol (3-MCPD) is the main chloropropanol found in hydrolyzates of vegetable protein (HVP) made by acid hydrolysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Crews, C., et al.: Food Addit. Contam., 18, 271 (2001), Hamlet, C., et al.: Food Addit. Contam., 19, 15 (2002), Weisshaar, R., et al.: Eur. J. Lipid Sci. Technol., 112, 158 (2010),<br></p>

<p>Applications 3-(4-Hydroxyphenyl)-1-propanol is a reagent in the synthesis of heteroarylmethoxyphenylalkoxyiminoalkylcarboxylic acids as leukotriene biosynthesis inhibitors.<br>References Kolasa, T. et al.: J. Med. Chem., 43, 690 (2000); Brooks, C., et al.: J. Med. Chem., 39, 2629 (1996)<br></p>

<p>Applications Benzenesulfonamide can be used to develop carbonic anhydrase inhibitors. Benzenesulfonamide derivatives are also potential drug candidates for treating cancer.<br>References Abdel-Aziz, A. A., et al.: Bioorg Med Chem. 25, 1666 (2017); Bhatt, A., et al.: Chembiochem 18, 213 (2017)<br></p>

<p>Applications A nicotinic receptor agonist; brain rubidium efflux pharmacol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Alkondon, M., et al.: J. Pharmacol. Exp. Ther., 271, 494 (1994); Wang, F., et al.: J. Biol. Chem., 271, 17656 (1996); Corringer, P., et al.: J. Neurosci., 18, 648 (1998);<br></p>

<p>Applications Anti-inflammatory glucocorticoid related to Enoxolone. Antiulcerative.<br>References Rask-Madsen, J., et al.: Eur. J. Clin.Invest., 13, 351 (1983), Minuz, P., et al.: Pharmacol. Res. Commun., 16, 875 (1984), Pindato, S., et al.: Anal. Profiles Drug Subs. Excip., 24, 1 (1996),<br></p>

<p>Applications N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.<br>References Hellman, B., et al.: Metabol. Clinc. Experiment., 23, 839 (1974); Tozuka, Z., et al.: J. Pharma. Sci., 100, 4024 (2011);<br></p>

<p>Applications Hydroxypropyl Chitosan is an antibacterial used to make organic rectorite-based nanofibrous mats with bacterial inhibition. Hydroxypropyl Chitosanhas been shown to exhibit inhibitory effects on the levels of Fe, Zn and Ca in liver, heart, lung, spleen, kidney and femur at high dosages in mice.<br>References Deng, H., et. al.: J. Biotma. Sci-Polym. E., 24, 485 (2013); Wang, Z., et. al.: Int. J. Biol. Macromol., 64, 25 (2014);<br></p>

<p>Applications Diethyl Sulfone is a reagent used in the synthesis of heterocyclic compounds including of β-ketosulfones. Also used in the preparation of sulfone-based electrolytes for aluminum electrodeposition.<br>References Legrand, L.. et al.: Electrochem. Act., 40, 1711 (1995); Katritzky, A. et al.: J. Org. Chem., 68, 1443 (2003);<br></p>