Building Blocks

<p>6-Mercaptopurine is a purine analog that suppresses the production of white blood cells by inhibiting the enzyme thiopurine methyltransferase. It has been used to treat bowel disease and also for long-term suppression of the immune system in patients with autoimmune diseases. 6-Mercaptopurine is metabolized to 6-mercaptopurine, which is then converted to dinucleotide phosphate (dNTP) by group P2 enzymes. This conversion allows 6-mercaptopurine to inhibit dNTP synthesis and cell division. The effects of 6-mercaptopurine are potentiated when given in conjunction with azathioprine, another drug that inhibits purine metabolism. 6-Mercaptopurine is not active against human serum albumin or erythrocytes because it cannot be cleaved into an active form by these proteins. However, it does inhibit enzyme activities such as DNA polymerase, RNA polymerase, and protein</p>

<p>6-Chloro-7-iodo-7-deazapurine is a nucleoside analogue that is synthesized by a cross-coupling reaction between 6-chloro-2,4(1H,3H)-pyrimidinedione and 7-iodo-7-(trifluoromethyl)purine. 6CIDP has been shown to inhibit growth of epidermal cells at concentrations as low as 0.1 µM, with cytostatic effects seen at 10 µM. 6CIDP has also been shown to potently inhibit the replication of the human papilloma virus in vitro and in vivo. 6CIDP is currently being investigated for the treatment of AIDS and other viral infections. The molecular modeling studies on this compound have revealed that it may be a potent inhibitor of the epidermal growth factor receptor (EGFR).</p>

<p>2-Chloro-1,1,1-trimethoxyethane is a reagent that is used in the synthesis of recombinant proteins. It is also used to produce monoclonal antibodies. Fatty acids can be analyzed by using these reagents as they are soluble in this solvent. The structural analysis of fatty acids has been shown to have anticancer activity. 2-Chloro-1,1,1-trimethoxyethane reacts with glycosyl residues on lysine residues in proteins and produces an acid that causes the protein to unfold and denature. This reaction has been shown to have anticancer activity against cervical cancer cells in human liver cells.</p>

<p>6-Methyluracil is an antimetabolite that inhibits protein synthesis and is therefore used in the treatment of infectious diseases. 6-Methyluracil has two hydroxyl groups, which are located in adjacent positions on the ring. The optimum concentration for this drug is 3-10 μM, which can be achieved with a malonic acid buffer solution at pH 7.4. 6-Methyluracil reacts with sodium succinate to form an acid complex, which may have antiinflammatory activity. 6-Methyluracil has been shown to inhibit prostaglandin synthesis and exhibits a reaction with radiation to produce photoproducts that can be detected by analytical chemistry.</p>

<p>Methanesulfinic acid sodium salt (MSAS) is a chemical compound that inhibits the growth of bacteria by inhibiting the synthesis of proteins. It is used as an antimicrobial agent in plant physiology and has been shown to be effective against infectious diseases including HIV infection. MSAS inhibits protein synthesis by binding to the hydroxyl group of a substrate molecule, which is required for amino acid formation. This inhibitory effect leads to a decrease in the production of proteins vital for cell division. Inhibiting protein synthesis also prevents the production of enzymes needed for metabolism, leading to metabolic disorders.</p>

<p>5-Chloro-2-methylaniline is an organic compound that is a member of the amines class. It has been shown to be genotoxic and carcinogenic in vivo. 5-Chloro-2-methylaniline binds to DNA and inhibits the synthesis of RNA, leading to cell death. It is also toxic to aquatic organisms by inhibiting cellular respiration and causing mutations. 5-Chloro-2-methylaniline has been shown to be genotoxic in vitro and in vivo, with chronic oral toxicity observed at dietary concentrations of 0.1% (10 ppm) in animals. The toxicity of this compound may be due to its ability to form hydrogen chloride when mixed with water or other acids.</p>

<p>2,4-Dinitrobenzaldehyde is a chemical compound that contains a hydroxyl group and an amine. It is reactive and can form cationic surfactants with other compounds. 2,4-Dinitrobenzaldehyde has been shown to react with dimethyl fumarate in the presence of ethyl esters to form ethyl 2,4-dinitrophenolate. This reaction is catalyzed by dinucleotide phosphate and requires salinity or a base such as sodium methoxide. 2,4-Dinitrobenzaldehyde reacts with 2-aminoethanol in the presence of water or alcohols to produce 2,4-diaminobenzoic acid. The reaction mechanism for this process is not known but it may involve hydrogen bonding between the hydroxyl group and amine groups.<br>2,4-Dinitrobenzaldehyde has been used as a reagent for staining DNA in gel elect</p>

<p>Monomer for the preparation of biocompatible polyurethane polymers</p>

<p>2,3-Dihydroxybenzoic acid is an antioxidant found in many plants. It has a protective effect against oxidative injury. 2,3-Dihydroxybenzoic acid has been used as a model for the study of infectious diseases and its effects on biological studies. This compound has been shown to prevent the growth of Aerobacter aerogenes and Dinucleotide phosphate. 2,3-Dihydroxybenzoic acid is also used as an ingredient in sephadex g-100 and it acts as an antimicrobial agent that prevents microbial growth in wastewater treatment systems.</p>

<p>cis-4,7,10,13,16,19-Docosahexaenoic acid (also known as DHA or cervonic acid) is one of the omega-3 fatty acids (a group of highly unsaturated fatty acids). As for most omega-3 fatty acids, good sources of DHA include fish oils and other seafoods. DHA plays a key role in human brain development and function and is also found in high concentration in the retina, central nervous system and skin. As such DHA is a key nutrient which is widely used as a dietary supplement, particularly for infants and pregnant women, with its potential health benefits currently being investigated across a number of different disease areas.</p>

<p>3,4-Dihydroxybenzoic acid ethyl ester (3,4-DHBA) is a phenolic compound that is used in the treatment of hepatic steatosis. 3,4-DHBA has been shown to be effective in inhibiting autophagy and may also be useful in the treatment of her2+ breast cancer. This drug has antioxidative properties and may also have a protective effect against myocardial infarct. 3,4-DHBA binds to iron ions and prevents their oxidation, thereby preventing oxidative stress. It has been shown to have low potency due to its short half-life in vivo. 3,4-DHBA can inhibit the mitochondrial membrane potential and lead to apoptosis of primary cells and tissue culture cells.</p>

<p>For fluorometric measurement of nitrite/nitrate in cells; inhibits NO production</p>

<p>1,3-Dimethoxybenzene is a carbonyl compound with the chemical formula C6H4(OCH2)2. It is soluble in water and has a boiling point of 176 °C. This compound reacts with hydrochloric acid to produce an intermediate acid chloride and hydrogen chloride gas. 1,3-Dimethoxybenzene also reacts with trifluoromethanesulfonic acid to produce an intermediate sulfonium salt and hydrogen fluoride gas. 1,3-Dimethoxybenzene can be used as a reagent for analytical methods such as IR spectroscopy, NMR spectroscopy, or mass spectrometry. When 1,3-dimethoxybenzene is combined with sodium hydroxide and acetic acid it forms an isothiouronium salt that can be used to study the effects of fatty acids on physiological activity.<br>1,3-Dimethoxybenzene has conformational</p>

<p>5-(Methylsulfanyl)pyrazin-2-amine is an organic chemical compound that is a useful building block, reagent, and research chemical. It has many uses in the synthesis of other compounds. 5-(Methylsulfanyl)pyrazin-2-amine is a versatile building block for complex compounds. This compound can be used as a reaction component or scaffold to produce desired products. 5-(Methylsulfanyl)pyrazin-2-amine can also be used as a speciality chemical or high quality fine chemical.</p>

<p>Please enquire for more information about 4,5-Dicyanoimidazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,3-Dimethylbenzofuran (2,3-DBF) is a specific interaction that is an inorganic chemical. It has shown genotoxic effects, such as DNA damage and chromosomal aberrations, in hl-60 cells. 2,3-DBF can be acetylated by the activity of acetyltransferases to form 2,3-dimethylbenzoic acid (DMBA). DMBA is oxidized by cytochrome P450 enzymes to form DMBA quinone. DMBA quinone reacts with deuterium isotope to form an ionizable compound which can then be hydrolyzed into benzoic acid and methyl alcohol. The oxidation products of 2,3-DBF have been studied using analytical methods such as gas chromatography and mass spectrometry. These analyses showed the presence of acidic hydrolysis products and ionizable compounds.</p>

<p>4,6-Dimethyl-2-mercaptopyrimidine is a protonated form of the compound 4,6-dimethylpyrimidine. It is a member of the group p2 of nitrogenous bases and has a hydrogen bond interaction with its base pair. The reaction mechanism for this molecule is similar to that of other tricyclic antidepressant drugs, as it involves an intermolecular hydrogen bonding reaction where the deprotonated hydroxyl group on one molecule transfers a proton to the adjacent nitrogen atom on another molecule. 4,6-Dimethyl-2-mercaptopyrimidine has been shown to be active in cervical cancer cells and is capable of inhibiting DNA synthesis and protein synthesis. This compound also has antihistamine effects which are likely due to its hydrogen bonding interactions with histamine receptors.</p>

<p>2,4-Dichloropyrimidine is a compound with an antiproliferation activity that has been shown to inhibit replication of viruses such as HIV. It inhibits the activity of enzymes involved in the replication of viral DNA, including the enzyme human telomerase reverse transcriptase (hTERT), which is essential for viral replication. The effects of 2,4-dichloropyrimidine on wild-type HIV are not clear because it does not have a significant effect on HIV-1 strains that have acquired resistance to erythromycin and tetracycline. However, this drug may be effective against other viruses that have not yet developed resistance. 2,4-Dichloropyrimidine also has antiinflammatory properties due to its ability to inhibit the production of epidermal growth factor and nitrogenous compounds from inflammatory cells.</p>

<p>(S)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine and its enantiomer, (R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine, are also known as Schöllkopf chiral auxiliaries or Schöllkopf reagents, and are used to produce optically pure α-amino acids via asymmetric synthesis. The Schöllkopf reagent can be deprotonated at the prochiral α-carbon, and the resulting enolate is trapped with electrophiles to yield adducts with high (typically &gt; 95% d.e.) diastereoselectivity. The enolate is essentially planar, and the steric bulk of the isopropyl group directs the incoming electrophile to attack from the opposite face, yielding trans adducts. A wide range of electrophiles including alkyl halides, alkyl sulfonates, acyl chlorides, aldehydes, ketones, epoxides, thioketones and enones can be used. Hydrolysis, typically under mild acidic conditions, yields the non-substituted amino acid with high (typically &gt; 95 e.e.) enantiopurity.</p>

<p>1,3-Dibromoadamantane is an organic compound that belongs to the group of organobromides. It has a chemical structure with three bromine atoms and one carbon atom, which are bonded to each other in a triangle shape. 1,3-Dibromoadamantane is soluble in solvents such as water and methanol. The reaction yield of 1,3-dibromoadamantane is 100% when it reacts with hydrochloric acid as the catalyst under optimal conditions. The reaction also occurs at a high temperature (100 degrees Celsius) and releases energy efficiently. 1,3-Dibromoadamantane can be used as a substrate molecule for the Suzuki coupling reaction.<br>The coordination chemistry of 1,3-dibromoadamantane involves the formation of a square planar complex with copper ions and ammonia molecules to form copper(I) ammine complexes, which are then able to bind</p>