Building Blocks

<p>Applications Ethyl Cinnamate, is used in the preparation of polymer-encapsulated osmonium used as a catalyst for the dihydroxylation of alkenes and preparation of a camptothecin intermediate, anticancer drug. Also used in the synthesis of substrate specific ERK1/2 inhibitors used to induce apoptosis and inhibit cell proliferation.<br>References Akiyama, R. et al.: RSC Adv., 2, 7456 (2012); Li, Q. et al.: Bioorg. Med. Chem. Lett., 19, 6042 (2009);<br></p>

<p>Applications Reagent used in labelled pyrimidine and purine synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Das, S., et al.: J. Med. Chem., 52, 5937 (2009), Kim, K., et al.: Bioorg. Med. Chem. Lett., 19, 5225 (2009),<br></p>

<p>Applications Ethyl Diazoacetate is used in the synthesis of Arteludovicinolide A as well as pyrimidoazepine analogs as seritonin 5-HT2A/C receptor ligands for treatment of obesity. This compound contains solvent for added stability.<br> E0<br>References Yang, H. et al.: Eur. J. Med. Chem., 63, 558 (2013); Kreuzer, A. et al.: Org. Lett., 15, 3420 (2013);<br></p>

<p>Applications Ethyl difluoroacetate<br></p>

<p>Applications 3-Ethyl-2,4-dimethyl-1H-pyrrole is a important diagnostic compound for pyrrole disorder or pyroluria, an abnormality in biochemistry resulting in overproduction of pyrrole molecules and resulting in improper hemoglobin synthesis.<br>References Walsh, W.J., et al.: Physiol. Behav., 82, 835 (2004); Inrvine, D.G., et al.: Clin. Chem., 24, 2069 (1978);<br></p>

<p>Applications (1R,5S,6R)-Ethyl 5-(Pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate is the enantiomer of Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate (E917820), an intermediate of Oseltamivir.<br>References Clark, C., et al.: J. Med. Chem., 31, 831 (1988)<br></p>

<p>Applications Ethylenediamine Dihydrochloride (cas# 333-18-6) is a useful research chemical.<br></p>

<p>Stability Air Sensitive, Hygroscopic<br>Applications 2-Ethylhexyl-4-aminobenzoate is an impurity in the synthesis of Ethylhexyl Triazone (E918810), used in sunscreen formulations as a UV filter to block out harmful ultraviolet light.<br>References Potard, G. et al.: Int. J. Pharm., 189, 249 (1999); Couteau, C. et al.: J. Pharm. Biomed. Anal., 44, 270 (2007);<br></p>

<p>Applications Ethyl hydrazinoacetate, HCl<br></p>

<p>Stability Volatile<br>Applications 5-Ethylidene-2-norbornene is a diene monomer that is used as a self healing agent for polymeric composites and also used to reinforce multiwalled carbon nanotubes. 5-Ethylidene-2-norbornene is potentially toxic to humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ballantyne, B., et al.: J. Appl. Toxicol., 17, 197 (1997); Jeong, W. &amp; Kessler, M.: Carbon, 47, 2406 (2009); Lee, J., et al.: Macromol. Res., 12, 478 (2004)<br></p>

<p>Applications Ethyl Isobutyrate is an ester found in fruity aromas in wines and used in varies fragrances.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gammacurta, M., et al.: J. Agr. Food. Chem., 62, 5378 (2014); Dourtoglou, V., et al.: Food Chem., 159, 181 (2014);<br></p>

<p>Applications Derivative of monoenoic and trienoic analogs of Sorbic Acid with antifungal activity.<br>References Guerin, J. et al.: Annales Pharmaceutiques Francaises 44, 373 (1987)<br></p>

<p>Applications 3-O-Ethyl-L-ascorbic Acid could be a useful stabilizing agent for a para-​hydroxyacetophenone solution.<br>References Zhang, H., et al.: Faming Zhuanli Shenqing (2020), CN 111937874 A<br></p>

<p>Applications Ethylmalonic Acid is used as a diagnostic agent used in the diagnosis of Ethylmalonic encephalopathy which is a rare autosomal recessive inborn error of metabolism.<br>References Baertling, F. et al.: Eur. J. Pediat., 173, 1719 (2014); Sudo, Y. et al.: Hu,am Genome Var., 1, 15016 (2014);<br></p>

<p>Stability Moisture Sensitive<br>Applications Ethyl Malonyl Chloride is used as a reagent in the synthesis of novel thiadiazoloacrylamide analogs as inhibitors of dengue-2 virus NS2B/NS3 protease. Ethyl Malonyl Chloride is also used as a reagent in the synthesis of quinolone-benzylpiperidine derivatives as acetylcholinesterase inhibitors and antioxidant hybrids for Alzheimer disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, H., et al.: Bioorg. Med. Chem., 22, 6344 (2014); Pudlo, M., et al.: Bioorg. Med. Chem., 22, 2496 (2014)<br></p>

<p>Applications 2-Ethyl-2-methylpentanoic Acid is a derivative of 2,5-Dimethyl-2-ethylhexanoic Acid (D461540), used in biological studies to evaluate environmental chemicals for estrogenicity.<br>References Rabinowitz, J.R., et al.: Chem. Res. Toxicol.,22, 1594 (2009); Judson, R., et al.: Environ. Health Perspect, 117, 685 (2009)<br></p>