Building Blocks

<p>Applications Cyclopentanone-2,2,5,5-d4 (CAS# 3997-89-5) is a useful isotopically labeled research compound.<br></p>

<p>Stability Moisture Sensitive<br>Applications Isopentyl Mesylate is used as a reagent in the synthesis of phosphonate derivatives as autotaxin (ATX) inhibitors.<br>References Cui, P., et al.: Bioorg. Med. Chem. Lett., 17, 1634 (2007)<br></p>

<p>Applications Fatty acid ester with glycerol chlorohydrins shows mutagenic activity.<br>References Janis, R., et al.: J. Food Lipids, 13, 199 (2006), Seefelder, W. et. al.: Food Additiv. Contamin., 1, 10 (2007)<br></p>

<p>Applications Benzylamine Hydrochloride (cas# 3287-99-8) is a useful research chemical.<br></p>

<p>Applications 3-Methylindole metabolite.<br>References Skordos, K., et al.: Chem. Res. Toxicol., 11, 741 (1998), Lanza, D., et al.: Drug Metab. Disposition, 29, 950 (2001), Hoenicke, K., et al.: J. Agric. Food Chem., 50, 4303 (2002),<br></p>

<p>Applications 4-Methylmorpholine is used in the synthesis of novel and selective TYK2 inhibitors, used in the treatment of inflammatory diseases. Also used in the preparation of cathespin K inhibitors which are highly selective.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liang, J. et al.: Eur. J. Med. Chem., 67, 175 (2013); Yuan, X. et al.: Org. Biomol. Chem., 11, 5847 (2013);<br></p>

<p>Applications 3-Cyclohexenylcarboxylic Acid has been found to be an oxidizable, nongrowth substrate and induces the metabolism of cyclohexanecarboxylic acid and benzoic acid in a strain of Pseudomonas putida. 3-Cyclohexenylcarboxylic Acid has been used as food for cultures of Streptomyces sp.  KCTC 11604BP fkbO deletion mutant to make 32-dehydroxy-FK506, a FK506 analogue containing a non-natural starter unit.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blakley, E.R., Papish, B.: Can. J. Microbiol., 28, 1324 (1982); Ban, Y.H., et. al.: Mol. bioSystems, 9, 944 (2013)<br></p>

<p>Applications o-Iodohippuric Acid is used as a probe to measure renal function and clearance.<br>References Galinsky, R. et al.: Mech. Age. Dev., 56, 209 (1990);<br></p>

<p>Applications N-Methylformanilide is an aromatic reagent used in the synthesis of dye-sensitized solar cells. Also used in the synthesis of potent tyrosinase inhibitors.<br>References Meyer, T et al.: J. Org. Chem., 77, 3704 (2012); Nihei, K. et al.: Bioorg. Med. Chem. Lett., 14, 681 (2004);<br></p>

<p>Applications 4-(1-Methylethyl)benzoic Acid is used in the synthesis of quinuclidine benzamides as agonists for nicotinic acetylcholine receptors. Also used in the synthesis of nifuroxazide analogues showing antimicrobial activity against methicillin-resistant Staphylococcus.<br>References Bodnar, A. et al.: J. Med. Chem., 48, 905 (2005); Masunari, A. et al.: Bioorg. Med. Chem. Lett., 15, 4229 (2007);<br></p>

<p>Applications 4-Methyl-6-(methylamino)-1,3,5-triazin-2(1H)-one is a heterocyclic Triazine based building block useful in organic synthesis. It is related to 2-Amino-4-methoxy-6-methyl-1,3,5-triazine (A616880), which is used to synthesize pesticides.<br>References Klein, J., et al.: J. AOAC Intrnational, 86, 1015 (2003); Pang, G., et al.: J. Chromat. A, 1125, 1 (2006);<br></p>

<p>Applications 1-(Bromoacetyl)pyrene is a novel photoinitiator.<br></p>

<p>Applications N-Methylacetamide can be used for the synthesis of N-​sulfonyl amidines and acyl sulfonyl ureas.Environmental contaminants; food contaminants.<br>References Chow, S. Y., et al.: J. Org. Chem. 82, 2515 (2017)<br></p>

<p>Applications 2-(Methylamino)ethanol used in the preparation of anticholesteremic, antilipemic and antioxidant biphenylylmorpholines. 2-(Methylamino)ethanol is also used in the preparation of enzyme inhibitors<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chrysselis, M., Rekka, E., Kourounakis, P. N.: J. Med. Chem. 43, 609 (2000); Ciayadi, R., et. al.: Bioorg. Med. Chem., 21, 6496 (2013); Labadie, S., et. al.: Bioorg. Med. Chem. Lett., 23, 5923 (2013)<br></p>