Building Blocks

<p>Applications Cyclooctatetraene is used as a reactant in the synthesis of tricyclo[4.2.2.02,5]dec-9-ene-3,4,7,8-tetracarboxylic acid diimide, an antitumor drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vishnuvajjala, B.R., Cradock, J.C.: J. Pharm. Sci., 75, 301 (1986)<br></p>

<p>Applications Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014); Keaney, E.P., et al.: Bioorg. Med. Chem. Lett., 24, 3714 (2014)<br></p>

<p>Applications O,N-Aminomethanylylidene-β-D-arabinofuranose (cas# 27963-98-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,3,5-Cycloheptatriene functions as a ligand in organometallic chemistry and also as a building block in organic synthetic processes. 1,3,5-Cycloheptatriene is applied in cycloheptatrienyl transition zirconium complexes formation and in other organic complex formation processes.<br>References Gloeckner, A., et al.: Chem. Soc. Rev., 42, 128 (2013); Massard, A., et al.: Organometallics, 31, 947 (2012); Kettles, T., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2012)<br></p>

<p>Stability Light Sensitive, Decomposes Rapidly in Air, Temperature Sensitive<br>Applications It has been examined as a ligand and as a pseudo-cyanide.<br></p>

<p>Impurity Anastrozole Monoacid Impurity<br>Applications Anastrozole Mono Acid is an impurity of Anastrozole (A637435), an aromatase enzyme inhibitor and antineoplastic agent. Anastrozole Monoacid Impurity<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>

<p>Applications (S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanoic acid (cas# 3303-31-9) is a useful research chemical.<br></p>

<p>Applications 3-(4-Chlorophenyl)propan-1-ol is used in preparation of 2-Oxo-2H-chromene-3-carboxylic Acid Amide derivatives as Aldo-Keto reductase inhibitors.<br>References Toyooka, N., et al.: Jpn. Kokai Tokkyo Koho, (2018);<br></p>

<p>Applications 2-(CHLOROMETHYL)NAPHTHALENE (cas# 2506-41-4) is a useful research chemical.<br></p>

<p>Applications Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.<br>References Zhou, J. et al.: Jiang. Dax. Xueb. Yixueb., 19, 475 (2009); Hsu, Y.L. et al.: J. Pharmacol. Exp. Ther., 313, 333 (2005);<br></p>

<p>Stability Hygroscopic<br>Applications A useful intermediate in the synthesis of polypeptides.<br>References Gobbini, M., et al.: J. Med. Chem., 51, 4601 (2008),<br></p>

<p>Applications A benzoic acid derivative used in photolysis reactions and biomaterial studies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wetzels, G.M. et al.: Biomaterials., 20, 1879 (1999); Mao, C. et al.: Adv. Coll. Int. Sci., 110, 5 (2004);<br></p>

<p>Applications 3-Chlorosalicylic Acid (cas# 1829-32-9) is a compound useful in organic synthesis.<br>References Shackelford, J.M.: J.O.C., 26, 4908 (1961)<br></p>

<p>Applications 1-(2H-1,3-benzodioxol-5-yl)propan-2-ol (cas# 6974-61-4) is a useful research chemical.<br></p>

<p>Applications 2-(4-CHLOROPHENYL)PROPANOIC ACID (cas# 938-95-4) is a useful research chemical.<br></p>

<p>Applications 5-Chloronaphthalene-2-sulfonyl Chloride (cas# 89108-45-2) is a compound useful in organic synthesis.<br></p>