Building Blocks

<p>Applications Monomethyl Suberate was used in the synthetic preparation of Prostaglandin E1 (P838600), a primary prostaglandin and a peripheral vasodilator.<br>References Rodriguez, A., et al.: Euro. J. Org. Chem., 10, 2655 (1999); Longmuir, K.J., et al.: Anal. Biochem., 167, 213 (1987);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Deoxy-D-arabino-hexonic Acid Calcium Salt has been shown to not play a major role in the initial hydrothermal decarboxylation of biomass.<br>References Luijkx, G.C.A., et. al.: Carbohyd. Res., 272, 191 (1995)<br></p>

<p>Applications 2,4-DIAMINOPTERIDINE-6-CARBOXYLIC ACID (cas# 716-74-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 3-Deoxy-D-manno-2-octulosonic Acid Ammonium Salt is a ketosidic component in all lipopolysaccharides of Gram-negative bacteria and has been identified in several acidic exopolysaccharides (K-antigens). Synthetic analogues of KDO may be studied for their potential to disrupt the biosynthesis of bacterial cell-wall components, and lead to new antibacterial agents.<br>References Altschul, S., et al.: J. Mol. Biol., 215, 403 (1990), Baumann, H., et al.: Biochemistry, 31, 4081 (1992), Hashimoto, M., et al.: Eur. J. Biochem., 268, 3139 (2001), Kodar, K., et al.: Immunol. Invest., 38, 704 (2009),<br></p>

<p>Applications Z-2-Fluoro-3-(3-pyridyl)acrylic Acid (cas# 359435-42-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Mono-Ethyl Malonate-1,2,3-13C3 (cas# 1189981-54-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-azidopyridine (cas# 39910-67-3) is a useful research chemical.<br></p>

<p>Applications (cas# 526-83-0) is a useful research chemical.<br></p>

<p>Applications Mono and dibasic phosphate esters are anionic surfactants which have the main feature of the stability in alkaline conditions over other surfactants. They have a wide range of properties including outstanding wetting, emulsification, lubrication, coupling activity and detergency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ramirez, F., et al.: Tetrahedron, 35, 1581 (1979);<br></p>

<p>Applications Mono-tert-butyl Succinate is a reagent used for the synthesis of fluorinated β2- and β3-amino acids, an inhibitor of α-chymotrypsin.<br>References Peddie, V., et al.: Synthesis, 1845-1859 (2010);<br></p>

<p>Impurity Indomethacin EP Impurity B<br>Applications N-Deschlorobenzoyl Indomethacin (Indomethacin EP Impurity B) is a metabolite of Indomethacin.<br>References O'Brien, W., et al.: Clin. Pharmacol. Ther., 9, 94 (1968), Duggan, D., et al.: J. Pharmacol. Exp. Ther., 181, 563 (1972), Abourashed, E., et al.: Curr. Med. Chem., 6, 359 (1999), Chatterjee, P., et al.: J. Nat. Prod., 62, 761 (1999),<br></p>

<p>Applications Bicyclo[2.2.1]hept-2-ene is a catalyst used in many reactions such as in the cascade cyclizations of iodoarene, bromobenzylamine, and electron-deficient alkene derivatives and arene C-H amination with aryl halides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Narbonne, V., et. al.: Org. Lett., 16, 628 (2014); Dong, Z., Dong, G.: J. Am. Chem. Soc., 135, 18350 (2013)<br></p>

<p>Applications α-Desethyl Butamirate is an impurity in the synthesis of Butamirate (B690025), an antitussive drug.<br>References Wang, T., et al.: J. Pharm. Biomed. Anal., 23, 867 (2000), Lasztity, A., et al.: Microchem. J., 73, 59 (2002), Wang, L., et al.: J. Pharm. Biomed. Anal., 33, 961 (2003), Lewen, N., et al.: J. Pharm. Biomed. Anal., 35, 739 (2004),<br></p>

<p>Applications Monobenzyl Malonate is a useful synthetic intermediate. It was used to synthesize constrained cyclic agonists of the cholecystokinin CCK-B receptor. It was also used to prepare aspartate transcarbamoylase inhibitors.<br>References Blommaert, A., et al.: J. Med. Chem., 40, 647 (1997); Coudray, L., et al.: Bioorg. Med. Chem., 17, 7680 (2009)<br></p>

<p>Applications A optically active metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>

<p>Applications 1,3-Diacetin is a derivative of Triacetin (T720850) which is used as a food additive and flavorings. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>