Building Blocks

<p>Applications Methyl 4-Methoxyphenylacetate (cas# 23786-14-3) is a useful research chemical.<br></p>

<p>Applications Diethyl Phenylmalonate is a reagent used in the synthesis of antituberculosis agents.<br>References Ng, P. S., et al.: J. Med. Chem., 106, 144-156 (2015)<br></p>

<p>Applications Diethyl Phosphite, is an phosphorous precursor used for the synthesis of various organophosphorus compounds, acting as insecticide, and pesticides.<br>References Kjoelholt, J., et al.: Chemosphere, 14, 1763 (1985); Zhou, Q., et al.: Atmospheric Environ., 43, 4163 (2009);<br></p>

<p>Applications A propargyl derivative used in the synthesis of substituted carbocyclic aromatic compounds and pharmaceutical compounds.<br>References Takahashi, H. et al.: J. Org. Chem., 74, 3632 (2009); Ding, F. &amp; Jennings, M.: J. Org. Chem., 73, 5965 (2008)<br></p>

<p>Applications (1-Ethoxycyclopropoxy)trimethylsilane used as a reactant in the synthesis of di-, tri- and tetracyclopropylhydrazines. Also used as reagent in the synthesis of g elsemoxonine which is found in gelsemium plant species that is used in traditional asian medicine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shestakov, A., et al.: Chem. Commun., 52, 2398 (2016); Diethelm, S., et al.: J. Am. Chem. Soc., 137, 6084 (2015);<br></p>

<p>Applications N,N-Dimethylmethyleneiminium Iodide (cas# 33797-51-2) is a useful research chemical.<br></p>

<p>Applications 3-Amino-4-methylpyridine (cas# 3430-27-1) is a compound useful in organic synthesis.<br>References Huang, H., et al.: Anal. Biochem., 363, 12 (2007), Tucker, T., et al.: J. Med. Chem., 51, 6503 (2008),<br></p>

<p>Applications Intermediate in the preparation of Ertapenem (E635000).<br></p>

<p>Applications (E)-2-Pentenal, is a flavor volatile found in tomato, virgin olive oil and sardine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.The intermediate, 2-mercaptohistine has been used for the<br>References Makinen, K.K., et al.: Eur. J. Biochem., 123, 171 (1982), Howard, R.J., et al.: Biochem. Pharmacol., 35, 1589 (1986),<br></p>

<p>Applications 3-(Aminomethyl)pyridine is a compound useful in organic synthesis. A pyridine derivative with vasodilating activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Uno, B. E., et al.: Adv. Syn. Catal., 360, 1719 (2018); Trcka, V., et al.: Pharmazie, 11, 242 (1956)<br></p>

<p>Applications 2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid-d3 (cas# 1346604-53-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Isobutyric Anhydride is used as a highly reactive and non-water producing acyl donor for hydrolase-catalyzed enantioselective esterification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, J.-H., et al.: Appl. Microbiol. Biot., 43, 402 (1995)<br></p>

<p>Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boettecher, B. &amp; Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)<br></p>

<p>Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.<br>References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)<br></p>

<p>Applications 1-Bromobutane-2,2,3,3,4,4,4-d7 (CAS# 223487-53-4) is a useful isotopically labeled research compound.<br></p>