Building Blocks

<p>Stability Hygroscopic<br>Applications 3-Amino-3-azabicyclo[3,3,0]octane is used as a reactant in the synthesis of Gliclazide (G409875), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972); Holmes, B., et al.: Drugs, 27, 301 (1984)<br></p>

<p>Applications 2-Mercaptothiazoline is an antithyroid agent that strongly reduces thyroid hormone levels. 2-Mercaptothiazoline is also used as an intermediate in the preparation of pesticides and other biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Thomes, J. et al.: Jap. J. Pharmacol., 58, 201 (1992); Buxeraud, J. et al.: Eur. J. Med. Chem., 20, 43 (1985); Cheng, J. et al.: Nongyao, 38, 12 (1999);<br></p>

<p>Applications A reagent used for the synthesis of hydroxylamines and hydroxyamates.<br>References Magin, D.F., et al.: J. Chromatogr., 178, 219 (1979), Safavy, A., et al.: Bioconjug. Chem., 13, 327 (2002),<br></p>

<p>Applications 1-methoxypropan-2-amine hydrochloride (cas# 677743-83-8) is a useful research chemical.<br></p>

<p>Applications 5-methoxypentanoic acid (cas# 70160-05-3) is a useful research chemical.<br></p>

<p>Applications 3-Chloro-2-methyl-1-propene has been used in the synthesis of 2-S-substituted pyrimidines as antimetabolites of nucleic acid precursors for cancer therapy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kaldrikyan, M.A., Melik-Ohanjanyan, R.G.: Hayastani Kimiakan Handes, 67, 321 (2014)<br></p>

<p>Applications 1-(Chloromethyl)naphthalene is used in the identification of Novel p38α MAP Kinase Inhibitors. It is also used in the Identification of 1,5-Naphthyridine derivatives as a novel series of potent and selective TGF-β type I receptor inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gill, A., et al.: J. Med. Chem., 48, 414 (2005); Gellibert, F., et al.: J. Med. Chem., 47, 4494 (2004)<br></p>

<p>Stability Air Sensitive<br>Applications Allyltributyltin is a reagent in the preparation of chiral hydropyrimidines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, Pu-Sheng, et al.: Angewandte Chemie, I.E., 56(50), 16032-16036 (2017)<br></p>

<p>Applications A potent inhibitor of gluconeogenesis.<br>References Blank, B., et al.: J. Med. Chem., 17, 1065 (1974), Memoli, K.A., Tetrahedron Letters, 37, 21, 3617 (1996)<br></p>

<p>Applications cis-1,3-O-Benzylideneglycerol (cas# 4141-19-9) is a compound useful in organic synthesis.<br></p>

<p>Applications (R)-1-(3-Pyridyl)ethanol (cas# 7606-26-0) is a useful research chemical.<br></p>

<p>Applications Mesitaldehyde (cas# 487-68-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Piperidineethanol (cas# 3040-44-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 4-(Bromomethyl)-3-methoxybenzoate is an intermediate used to prepare heteroarylphenyloxoacetyl and heteroarylphenylsulfonyl benzoylpiperazine analogs of BMS 378806 as HIV entry inhibitors. It is also used to synthesize steroid 5α-reductase inhibiting acylpiperidines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lu, R., et al.: J. Med. Chem., 52, 4481 (2009); Picard, F., et al.: J. Med. Chem., 45, 3406 (2002)<br></p>