Building Blocks

<p>Applications 2-Phenylbenzothiazole is an organic compound that was detected in water and sediment from sedimentation ponds as a contaminant.<br>References Grung, M., et al.: Sci. Total Environ., 751, 141808 (2021)<br></p>

<p>Applications 4-Imidazolecarboxaldehyde is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the treatemnet of androgen-dependent prostate cancer. 4-Imidazolecarboxaldehyde is also used in the synthesis of other biologically active compounds such as antimalarial drugs.<br>References Kawakami, J. et al.: Org. Proc. Res. Dev., 11, 206 (2007); Kalkanidis, M. et al.: Biochem. Pharmacol., 63, 833 (2002);<br></p>

<p>Applications 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid is a photoreactive aromatic diazirine.<br>References Wiedmann, M .; J. Cell biol.; 104, 201 (1987).<br></p>

<p>Stability Unstable in acidic solution<br>Applications Trimethyl Orthovalerate is used in the synthesis of dihydropyran-4-ones, via the Maitland-Japp reaction, which can be converted stereoselectively into tetrahydropyran-4-ones. This conversion is useful in the study of the functionalized tetrahydropyran units that are found in the anticancer polyketide lasonolide A and the Civet fragrance which is used in perfumery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Clarke, P., et al.: Org. Biomol. Chem., 13, 4743 (2015)<br></p>

<p>Stability Hygroscopic<br>Applications N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride (cas# 637-01-4) is a useful compound for membrane-tethering cytochrome c to study its impact on cell death in yeast.<br>References Toth, A., et al.: Cell Death Dis., 11, 722 (2020)<br></p>

<p>Applications 1,2-Octanediol is a novel surfactant used in the treatment of head louse. Also used in the cosmetics industry in the formulations of sunscreen gels and eye make-up.<br>References Dayan, N. et al.: Cosmet. Toilet., 126, 186 (2011); Georgalas, A. et al.: Cosmet. Toilet., 127, 96 (2012); Burgess, I. et al.: PLoS One., 7, e35419, (2012)<br></p>

<p>Applications Sodium 3-nitrobenzenesulfonate is a reagent in the synthesis of azetidinyl ketolides for treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.<br>References Magee, T.V., et al.: J. Med. Chem., 52, 7446 (2009);<br></p>

<p>Applications Nitrofurate is a useful organic reagent. It is used for preparation of polycyclic small molecules.<br>References Tan, D., et al.: J. Am. Chem. Soc., 121, 9073 (1999); Lu, P., et al.: Org. Lett., 11, 5710 (2009);<br></p>

<p>Applications Sodium 3-​(10H-​Phenothiazin-​10-​yl)​propane-​1-​sulfonate can be used in biological and analytical studies of a portable chemiluminescence imaging immunoassay for simultaneous detection of different isoforms of prostate specific antigen in serum.<br>References Liu, A., et al.: Biosens Bioelectron, 81, 97 (2016)<br></p>

<p>Applications Indole-2-carboxylic Acid (cas# 1477-50-5) is a compound useful in organic synthesis.<br></p>

<p>Applications A non detergent sulfobetaine used as a mild solubilizing and stabilizing agent for halophilic malate dehydrogenase, halophilic elongation factor Tu (hTu), pig heart malate dehydrogenase, chicken egg white lysozyme and E. coli beta-galactosidase. Preserves the antigenic conformation of serine protease gp76. Does not interfere with colorimetric assays using p-nitrophenylphosphate and o-nitrophenyl-b-D-galactopyranoside as substrates. Reduces aggregation and significantly improves protein renaturation. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Can be easily removed by dialysis.This compound is suitable for malate dehydrogenase (MDH) related research.<br>References Vuillard, L., et al.: Anal. Biochem., 230, 290 (1995); Vuillard, L., et al.: FEBS Lett., 353, 294 (1995); Vuillard, L., et al.: Biochem. J., 305, 337 (1995); Goldberg, M.E., et al.: Folding &amp; Design, 1, 21 (1996).<br></p>

<p>Applications N-3-(Sulfopropyl)-3-methoxy-5-methylaniline is used as a reagent for the evaluation of basic property and long-term stability of reagents for enzymically assaying triglyceride, cholesterol and uric acid.<br>References Yamaguchi, T., Iryo to Kensa Kiki-Shiyaku., 3, 591-597 (2007).<br></p>

<p>Applications Temsavir is a Fostemsavir (CAS# 864953-29-7) intermediate and an antiviral agent. It is an HIV-1 attachment inhibitor.<br>References Landry, I., et al.: Antimicrob. Agents Chemother., 60, 2782-2789 (2016);<br></p>

<p>Applications 2,5,6,7-tetrahydro-1H-azepin-2-one (cas# 2228-79-7) is a useful research chemical.<br></p>