Building Blocks

<p>Applications Formamide-d3 is labelled Formamide (F691780 ). Formamide (F691780) is a compound that is used in biochemistry to prevent RNA samples from degradation due to RNAses. Formamide (F691780) is also used as a plasticizer to prepare thermoplastic starch (TPS), a special type of starch that can be mixed with other synthetic polymers because of its unique ability to “flow”<br>References Chomczynski, P.: Nuc. Acids Res., 20, 3791 (1992); Ma, X. &amp; Yu, J.: Acta Polym. Sinica 2, No vol. given, 240 (2004); Rodriguez-Gonzalez, F., et al.: Polymer, 44, 1517 (2003); Shi, Q., et al.: Polym. Degrad. Stabil., 96, 175 (2011)<br></p>

<p>Applications Formamide-1-d1 (CAS# 35692-88-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications A labelled metabolite of Carnitine used in diagnostic screening of patients with inherited disorders of fatty acid oxidation.<br>References Johnson, D.W. et al.: Chem. Phys. Lipids, 129, 161 (2004);<br></p>

<p>Stability Light Sensitive<br>Applications α-Bromopropiophenone (cas# 2114-00-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-methyl-2-(morpholin-4-yl)propanoic Acid hydrochloride (cas# 375397-37-8) is a useful research chemical.<br></p>

<p>Applications Structure-mutagenic activity relationships in the Salmonella typhimurium TA100 strain in a series of short-chain halogenated hydrocarbons and alcohols.<br>References Eder, E., et al.: Biochem. Pharmacol., 29, 993 (1980), Neudecker, T., et al.: Mutat. Res., 170, 1 (1986), Lag, M., et al.: Chem. Res. Toxicol., 4, 528 (1991),<br></p>

<p>Applications 4(3H)-Pyrimidinone, is a derivative of Pyrimidone, that can be used as a building block for the preparation of many other biologically molecules, such as Metharbital. It has also been shown to present in the GU "wobble" pair.<br>References Semenov, D. A., et al.: arXiv.org, e-Print Archive, Physics, 1 (2012);<br></p>

<p>Applications 2-Bromo-4'-methoxyacetophenone is a α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.<br>References Taylor, W., et al.: Bioorg. Med. Chem., 4, 1515 (1996), Elchelby, M., et al.: Science, 283, 1544 (1999), Shen, K., et al.: J. Biol. Chem., 276, 47311 (2001), Wang, P., et al.: Biochemistry, 41, 6202 (2002),<br></p>

<p>Applications Isobutyryl chloride is a useful intermediate commonly used in synthetic chemistry. Isobutyryl chloride is also a potential inducer of pulmonary adenomas in strain A mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Theiss, J., et al.: Cancer Res., 39, 391 (1979)<br></p>

<p>Applications 3-Methyl-1,2-benzenediol is a common component of pyrolysis products.<br>References Jeong, Jae-Yong, et al.: Bioresource Tech., 219, 357-364 (2016);Chen, Dengyu, et al.: Bioresource Tech., 216, 629-636 (2016)<br></p>

<p>Applications 4-Bromo-2-fluorobenzoic Acid is a halogenated derivative of benzoic acid. 4-Bromo-2-fluorobenzoic Acid is used in the synthesis of pharmaceutically significant products such as d-Amino acid oxidase inhibitors.<br>References Katane, M., et al.: J. Med. Chem., 56, 1894 (2013); Vasbinder, M.M., et al.: J. Med. Chem., 56, 1996 (2013);<br></p>

<p>Applications 2-Bromo-4'-fluoroacetophenone-2',3',5',6'-d4 (CAS# 1219803-30-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Bromo-4’-fluoroacetophenone is an intermediate in the synthetic preparation of competitive inhibitors of aromatase.<br>References Utsukihara, T., et al.: J. Molec. Cata. B: Enzymatics., 45, 68 (2007); Vinh, T.K., et al.: Bioorg. Med. Chem. Lett., 9, 2105 (1999);<br></p>

<p>Applications 5-Bromofuran-2-carboxaldehyde used in the preparation of isoindolinones from furfural. Also used in the preparation of brominated nitrovinylfuran which displays antibacterial activity.<br>References Caillot, G. et al.: New. J. Chem,, 37, 1195 (2013); Scholz, T. et al.: Bioorg. Med. Chem. Lett., 21, 795 (2013);<br></p>

<p>Applications 4-Bromo-3-fluoroaniline is an intermediate used for the synthetic preparation of Tradizolid and various pharmaceuticals such as the synthesis of several lateral difluoro-substituted 4,4"-dialkyl- and 4,4"-alkoxyalkylterphenyls.<br>References Gray. G., et al.: Molec. Crystals. Liquid. Crystals., 204, 43 (1991); Ng, B.H., et al.: J. Chem. Soc., 2815 (1958);<br></p>

<p>Applications 1-Bromo-2,6-difluorobenzene-d3 (CAS# 1219803-73-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromo-3,5-difluorobenzene-d3 (CAS# 1219798-73-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 6-Bromo-3-cyanoindole<br></p>