Building Blocks

Applications 1,2-Hexanediol is used in the synthesis of sulfamidates which lead a simple route into β-amino acids. Also used in the controlled growth of GE nanowires.
References Nicolaou, K. et al.: Angew. Chem. Int. Ed., 41, 834 (2002); Lotty, O. et al.: J. Mat. Chem. C., Mat. Optic. Electro. Devices., 1, 4450 (2013);

Applications A silicon based compound that can be used to create potentially biocompatible materials. Used as a monomer in the synthesis of long chain polysiloxane structures. Used in the methylation of mercury(II) salts.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Radeva, E. et al.: J. Optoelec. Adv. Mat., 11, 1432 (2009); Gandhiraman, R.P. et al.: Plama Proc. Polym., 11, 1432 (2009); Watanabe, N. et al.: Ecotoxic. Env. Safety, 11, 174 (1986);

Applications Methyl 4-(Bromomethyl)-3-methoxybenzoate is an intermediate used to prepare heteroarylphenyloxoacetyl and heteroarylphenylsulfonyl benzoylpiperazine analogs of BMS 378806 as HIV entry inhibitors. It is also used to synthesize steroid 5α-reductase inhibiting acylpiperidines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lu, R., et al.: J. Med. Chem., 52, 4481 (2009); Picard, F., et al.: J. Med. Chem., 45, 3406 (2002)

Applications Intermediate in the preparation of P2X7 antagonists
References Donnelly-Roberts, D., et al.: Neuropharmacol., 56, 223 (2009), Perez-Medrano, A., et al.: J. Med. Chem., 52, 3366 (2009),

Applications 1-(4-Amino-3,5-dichlorophenyl)-2-ethanone (cas# 37148-48-4) is a compound useful in organic synthesis.

Applications 2-(4’-Chlorobenzoyl)benzoic Acid (cas# 85-56-3) is a compound useful in organic synthesis.

Applications trans-2-Nonenal is an unsaturated aldehyde that is a product of fatty acid peroxidation (and also has a grassy, cucumber smell). trans-2-Nonenal is naturally found in mushrooms, coffee and is also a constituent of carrot root. It also exhibits insecticidal effects.
References Chamberlain, D., et al.: J. Chem. Ecol., 17, 615 (1991); Guerin, P. & Ryan, M.: Experentia, 36, 1387 (1980); Parliment, T., et al.: J. Agr. Food Chem., 21, 485 (1973); Wood, W., et al.: Mycologia, No vol. given, 561 (1994)

Applications 4-(1H-1,2,4-triazol-1-yl)phenol (cas# 68337-15-5) is a useful research chemical.

Applications 4-Amino-2-chloro-3-methylbenzonitrile is a reagent used in synthesis of imidazolin-2-ones, which is designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs).
References Li, J. J., et al.: J. Med. Chem., 50, 3015-3025 (2007)

Applications Bromonitromethane is used in the preparaton of [2,3-d]pyrimidines as inhibitors of Lck which can be used in the treatment of diseases where T-cell proliferation is unwanted. It is also used in the synthesis of isoxazoline N-oxides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References DiMauro, E. et al.: Bioorg. Med. Chem. 17, 2305 (2007); Kunetsky, R. et al.: Org. Lett., 5, 4907 (2003);

Applications Acetamide-2,2,2-d3 is used in infrared spectral studies and normal vibrations of acetamide and it’s deutrated analogs.
References Suzuki, I., et al.: Bull. Chem. Soc. of Jpn., 35, 1279 (1962); Knudsen, R., et al.: J. Mol. Struct., 321, 187 (1994)

Stability Moisture Sensitive, Very Hygroscopic
Applications A Cyclophosphamide analog which induces apoptosis dose and time dependently in lymphoblastoid cells, with clearly more apoptosis in p53wt cells. Antitumor agent.
References Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999), Lips, J., et al.: Carcinogenesis, 22, 579 (2001), Ward, I., et al.: J. Biol. Chem., 276, 47759 (2001), Zhou, B., et al.: Cancer Biol. Ther., 2, S16 (2003), Roos, W., et al.: Oncogene, 26, 186 (2007),

Applications One of the alkyl ethers with tert-Bu groups in their molecules which showed very poor biodegradability, tert-Bu Me ether (MTBE)  [1634-04-4] had no effect on the biodegradability of gasoline blended with it. Studies on the biodegradation of several alkyl ethers were carried out by measuring the O uptake rate in the presence of standard activated sludge as a source of microorganisms.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siegemund, B., et al.: Acute Toxicity Data, 1, 200 (1992),

Applications α,2,4-Trichloroacetophenone is a reagent used in the synthesis of isoconazole, a potent antifungal agent.
References Dulcevscaia, G. et al.: Polyhed., 52, 106 (2013); Wang, Y. et al.: Bioorg. Med. Chem. Lett., 22, 5363 (2012);

Applications A metabolite of Tryptophan. 5-Hydroxytryptophan (5-HTP) is a direct 5-hydroxytryptamine (5-HT) precursor used to assess central serotonergic function.
References Gartside, S., et al.: Eur. J. Pharmacol., 179, 103 (1990), Gijsman, H., et al.: J. Clin. Psychopharmacol., 22, 183 (2002), Schruers, K., et al.: Psychiatry Res., 113, 237 (2002),

Applications Diethyl (6-methyl-2-pyridylaminomethylene)malonate is a useful reagent for pharmaceutical synthesis. It is used in the preparation of substituted quinoline carboxyguanidines which functions as an antidiabetic agents.
References Edmont, D., et al.: Bioorg. Med. Chem. Lett., 10, 1831 (2000); Chattopadhya, J., et al.: Indian J. Chem., Section B: Org. Chem. Med. Chem., 29B, 98 (1990); Richardson, A. J., et al.: J. Med. Chem., 15, 1203 (1972)

Applications 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is used in preparation and structure of alkaline earth iodide phosphine oxide and urea complexes as reactant or reagents.
References Fitts, Lacey S., et al.: New J. of Chem., (2016); Hall, Jessica E., et al.: Angew. Chem. Int. Ed., 55, 11153-11157 (2016)

Applications 2-Bromoiodobenzene was used in the synthesis of diarylamines. It was also a reactant used in Suzuki Coupling reactions.
References Buden, M., et al.: J. Org. Chem., 74, 4490 (2009); Wolfe, J., et al.: J. Am. Chem. Soc., 121, 9550 (1999)