Building Blocks

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl pyrrolidine-2-carboxylate is a solid catalyst that is used in the industrial preparation of polyvinyl chloride and pharmaceutical drugs. It has shown anti-cancer properties and can be used to treat cancer. Ethyl pyrrolidine-2-carboxylate has also been shown to have an effect on the biological function of ns3 protease, an enzyme that is implicated in diabetes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

4-(2,5-Dimethyl-pyrrol-1-yl)-phenylamine is an organic compound that is used as a sensor for benzene. The sensitivity of the sensor can be increased by attaching substituents to the benzene ring. The frequency of the sensor can be measured by atomic force microscopy. The impedance of the sensor can be measured by long-term measurements on a resonant circuit, which also has linearity and hysteresis properties. This compound has high sensitivity and is a good candidate for use in sensors.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>2-Amino-3-methylhexanoic acid is a synthetic amino acid analog of the branched-chain amino acids leucine, isoleucine, and valine. It was originally developed as a treatment for thrombosis, but has been found to have antiviral properties. 2-Amino-3-methylhexanoic acid inhibits the action of enzymes that catalyze reactions in the synthesis of polypeptides, such as proteases (thrombin inhibitors) and peptidases. 2-Amino-3-methylhexanoic acid also inhibits viruses by preventing their replication. It does this by hydrogen bonding interactions with the viral capsid and preventing access to the RNA genome or protein coat. The chemical reaction between 2-amino hexanoic acid and an acid solution produces carbon dioxide gas.</p>

6-Hydroxypyridazine-3-carboxamide is a potential anti-cancer drug that belongs to the class of allosteric modulators. It is a small molecule inhibitor of metabotropic glutamate receptor 4 (mGluR4). 6-Hydroxypyridazine-3-carboxamide has been shown to inhibit the proliferation and migration of cancer cells in vitro. In vivo studies have demonstrated that this drug can inhibit tumor growth and metastasis, decrease inflammation, and prolong survival time in mice bearing human lung cancer xenografts. 6-Hydroxypyridazine-3-carboxamide also inhibits c1–c4 alkyl esterases, which are responsible for the metabolism of many drugs.

<p>Versatile small molecule scaffold</p>

<p>(6-Methoxynaphthalen-2-yl)methanol is a fluorescent probe that reacts with cytosolic proteins. When (6-methoxynaphthalen-2-yl)methanol is incubated with human liver, the rate of reaction increases in proportion to the concentration of cytosolic proteins. This probe can be used to detect changes in the activity of dehydrogenase and aldehyde oxidase enzymes, which are responsible for the metabolism of alcohols and aldehydes. The fluorescence intensity also increases when (6-methoxynaphthalen-2-yl)methanol binds to proteins due to an increase in its chromophore.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold