Building Blocks

<p>1-Benzyl-6-chloro-1H,2H,3H-pyrrolo[3,2-c]pyridine-7-carbonitrile is an alkoxy compound that has been shown to react with amines and halogen to form pyridines. The compound also reacts with hydroxy groups and nucleophilic residues to form alkoxy groups. This reaction is catalyzed by hydroxy groups or a base such as sodium hydroxide or potassium hydroxide. 1-Benzyl-6-chloro-1H,2H,3H-pyrrolo[3,2-c]pyridine-7-carbonitrile can be used in the synthesis of polymers and plastics. It can also be used as a precursor for the synthesis of other compounds.</p>

Encainide is a class I antiarrhythmic drug that belongs to the group of class Ia drugs and inhibits the fast sodium channel. It slows the heart rate and decreases conduction velocity in cardiac tissue. Encainide has been shown to be effective against tachycardia and ventricular arrhythmias. It has been shown to have a stable dose-response curve as well as no known drug interactions. Encainide has also been shown to improve cardiac function by inhibiting the activity of beta-receptors in cardiac muscle, which may lead to increased contractility, improved relaxation, and increased blood flow. Encainide is mainly used for the treatment of arrhythmias in patients with certain heart conditions, such as papillary muscle dysfunction or cardiomyopathy.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3,3-Dimethyl-1,4-dioxan-2-one (DMDO) is a chiral compound that is used in organic synthesis as a chiral auxiliary. This molecule has been shown to be useful for the stereoselective polymerization of lactones, enolates, amides and aldehydes. DMDO has also been investigated for its ability to form spindle-like polymers with glycolide and optical activity. 3,3-Dimethyl-1,4-dioxan-2-one is soluble in common organic solvents such as chloroform and dichloromethane at room temperature and can be used for the preparation of microparticles with a diameter up to 50 µm. The high yield of this compound makes it an attractive alternative to other synthetic methods.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

2-[(6-Amino-1H-purin-8-yl)amino]ethan-1-ol (6APA) is a prodrug that is metabolized by the liver to 6-mercaptopurine (6MP). It is an antiinflammatory drug that has been shown to suppress collagen synthesis and inhibit the activity of proteases. 6APA is also used as a diagnostic agent for systemic diseases, such as reactive arthritis and systemic lupus erythematosus. This compound can be used in the treatment of inflammatory diseases, such as rheumatoid arthritis and Crohn's disease, due to its ability to inhibit the production of inflammatory compounds. The drug binds to affinity ligands which are associated with various proteins, including collagen. This binding prevents the formation of new proteins, which leads to cell death by inhibiting protein synthesis.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

2-(1H-1,3-Benzodiazol-2-yl)-1-phenylethanone is an unsymmetrical phenacyl chloride that is used in the synthesis of drugs. The generation of acidolysis products and the formation of active methylene compounds are catalyzed by 2-(1H-1,3-benzodiazol-2-yl)-1-phenylethanone. This compound is also used for the preparation of chlorides and methylhydrazones. Preparative methods for this compound involve thionyl chloride, hydrochloric acid, and phenylhydrazone.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>