Building Blocks

<p>5-Benzyloxy-2-bromobenzaldehyde is a polyphenolic compound. It has been shown to have antioxidant activity and inhibit the production of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6. This compound also inhibits the production of inflammatory mediators such as COX-2, lipoxygenase, nitric oxide synthase, and inducible nitric oxide synthase. 5-Benzyloxy-2-bromobenzaldehyde has also been shown to be effective in reducing inflammation in animal studies.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Methoxybenzenesulfonamido)propanoic acid is a pyrimidine derivative that has been shown to have pathological effects on the cornea and retina. It has been shown that 2-(4-methoxybenzenesulfonamido)propanoic acid inhibits angiogenesis, which may be due to its effect on vascular endothelial growth factor (VEGF). The crystal form of this compound is orthorhombic with space group P2(1)/c. The x-ray powder diffraction pattern of this compound shows peaks at 8.8, 10.6, 12.0, 13.3, 14.8, 18.1 degrees 2θ and the X-ray powder diffraction spectrum shows peaks at 7.5, 11.2 degrees 2θ in the range of 3 - 50 keV with an intensity ratio of 1:1:1:1:1:1:1 respectively</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(3-Methoxyphenyl)amino]acetic acid is a potent inhibitor of 3clpro. 2-[(3-Methoxyphenyl)amino]acetic acid has been shown to inhibit the activity of the enzymes with nanomolar potency in the micromolar range. This compound has been shown to have a high affinity for 3clpro and potent inhibitory activity against other proteases such as papain, subtilisin, and trypsin. The inhibition mechanism of 2-[(3-methoxyphenyl)amino]acetic acid is not fully understood but it has been hypothesized that this compound can bind to the active site of 3clpro via its moiety group. Modifications on the molecule have been shown to increase its inhibitory potency and affinity for 3clpro. Optimization studies have also been carried out by titration calorimetry experiments, which show that 2-[(3-</p>

<p>Versatile small molecule scaffold</p>

<p>1,2-Difluoro-4,5-dinitrobenzene is a nitro compound that has been used extensively in supramolecular chemistry. The cavity of the molecule is able to bind with fatty esters and other molecules with lipophilic properties. This property can be exploited for the encapsulation of biomolecules and other organic compounds. 1,2-Difluoro-4,5-dinitrobenzene has also been found to be reactive towards carboxylic acid groups at room temperature and higher temperatures. The nature of this molecule is reactive as it reacts with carbodiimides to form cyclic urea derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>