Building Blocks

<p>1-Benzyl-1H-indazole is a potential anticancer agent. It inhibits the polymerase chain reaction in vitro and has been shown to reduce locomotor activity in vivo. 1-Benzyl-1H-indazole binds to the active site of human DNA polymerase, thereby inhibiting the enzyme's ability to synthesize DNA. The low potency of this agent makes it an unlikely candidate for use as a therapeutic drug. This drug has also been shown to induce squamous cell carcinoma in mice when applied topically, but not when injected intraperitoneally. Additionally, 1-benzyl-1H-indazole has been shown to be effective against systolic pressure and choroidal neovascularization by reducing nucleotide levels and oxidative injury, respectively. In vivo studies have demonstrated that 1-benzyl-1H-indazole inhibits cyclase activity and intracellular Ca2+ levels, and may be a path</p>

<p>2-Benzyl-2H-indazole is an orally active drug that is used for the treatment of Parkinson's disease. It has a pharmacokinetic half-life of about 8 hours. 2-Benzyl-2H-indazole binds to the dopamine D2 receptor, which is a G protein coupled receptor. The drug inhibits the enzyme sulfonylating, which yields dopamine in a reaction mechanism similar to that of reserpine. 2-Benzyl-2H-indazole also has been shown to have medicinal potential as it can inhibit the hyperactivity induced by levodopa.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methyl-5-(propan-2-yl)cyclohex-2-en-1-one is a plant terpene that has been found to have antimicrobial properties. It has been shown to inhibit the growth of methicillin resistant Staphylococcus aureus (MRSA) and other bacteria, including Streptococcus pyogenes (group A streptococci). This compound is also known as carvone, which is an active ingredient in the spice turmeric. 2-Methyl-5-(propan-2-yl)cyclohex-2-en-1-one can be used in pharmaceutical preparations and may have applications in cancer treatment.</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,3,4-Tetrahydro-benzofuro[3,2-c]pyridine is a heterocycle that is an alpha-2 adrenoceptor antagonist. It has been shown to be effective in the treatment of depression and anxiety. The compound binds to the alpha-2 adrenoceptor and blocks its activation by norepinephrine. 1,2,3,4-Tetrahydro-benzofuro[3,2-c]pyridine has also been shown to have intraocular pressure lowering effects.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Iodomethyl)oxane is an iodinated derivative of oxane. It is a quinoline derivative, which is a class of drugs that inhibit the activity of the 5-HT4 receptor. This receptor has been shown to be associated with epidermoid carcinoma and Alzheimer's disease. 2-(Iodomethyl)oxane has been found to have potent cardiovascular effects in animal studies, and may be a potential treatment for cardiac disorders and kidney cancer. In addition, it has been shown to exhibit surfactant activity, which may contribute to its anticancer effects.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>