Building Blocks

<p>Versatile small molecule scaffold</p>

<p>5,6-Dimethoxynicotinaldehyde is a small molecule that has been shown to have anticancer activity. It has been shown to inhibit the transcription of androgen receptors in prostate cancer cells by binding to the DNA at these sites. 5,6-Dimethoxynicotinaldehyde also inhibits the expression of genes involved in cell proliferation and differentiation. This compound has been tested on several human cancer cell lines and was found to be active against prostate cancer cells, colon cancer cells, breast cancer cells, leukemia cells, and lymphoma cells. 5,6-Dimethoxynicotinaldehyde is not effective against normal cells due to its inability to cross the blood-brain barrier.</p>

<p>Versatile small molecule scaffold</p>

<p>8-Methyl-decahydroquinoline is a nitramine, which is a family of organic compounds that are related to the nitroaromatic compounds. 8-Methyl-decahydroquinoline has been shown to be formed by the dehydrogenation of quinoline. It has been found in the leaves and stems of the plant Nitraria erythrocarpa and in alkaloids from Nitraria plants. The spectra for this compound show bands at 1705, 1660, and 1635 cm−1. A mass spectrum for this compound shows peaks at m/z = 138, 130, 116, 114 and 110.</p>

<p>Versatile small molecule scaffold</p>

<p>3-tert-Butyl-1-(propan-2-yl)thiourea is a ketone that is used as a reagent for the synthesis of thioureas. It is also a precursor in organic synthesis. 3-tert-Butyl-1-(propan-2-yl)thiourea reacts with hydrochloric acid to form tertiary butyl alcohol, which then reacts with thiourea to produce 3-(propan-2-y)thiourea. This reaction yields a mixture of olefin and thioester products. The organic solvent can be removed by distillation, leaving the crystalline product behind. The final product is an aluminium salt of 3-(propan-2-y)thiourea.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5,5-Bis(propan-2-yl)imidazolidine-2,4-dione is a potent and selective antinociceptive agent. It has been shown to be effective in the treatment of chronic pain. 5,5-Bis(propan-2-yl)imidazolidine-2,4-dione has high potency and selectivity for the peripheral nervous system. It inhibits voltage dependent sodium channels which lead to decreased neuronal excitability. This drug also has anticonvulsant properties which may be due to its ability to inhibit glutamate release.</p>