Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-(4-Chlorophenyl)oxolane-2,5-dione is a telechelic monomer with a hydroxyl group at one end and an alkynyl group at the other. This molecule has functional groups that can be used in polymerization reactions to create polymers. It is often used as a precursor for polyesters, polyurethanes, and polyamides. 3-(4-Chlorophenyl)oxolane-2,5-dione reacts with metal ions to form polymers that emit light when excited by light. The fatty acid component of this molecule makes it soluble in hydrocarbon solvents such as hexane and heptane. 3-(4-Chlorophenyl)oxolane-2,5-dione can also be used to produce biodegradable plastics from renewable resources such as vegetable oils or soybean oil.

Dimethyl(quinolin-2-ylmethyl)amine is a chemical compound that has shown anti-cancer activity in humans. It is a precursor of the drug quinacrine, which is used to treat some types of cancer. Dimethyl(quinolin-2-ylmethyl)amine and related compounds are believed to work by interfering with DNA synthesis, preventing the proliferation of cancer cells.

N-Isopropylterephthalamic acid is a metabolite of terephthalic acid and is formed by the oxidation of isopropyl alcohol. The metabolism of N-isopropylterephthalamic acid in humans has been shown to be catalyzed by cytochrome P450 enzymes, which are expressed in the liver. This reaction occurs through a series of oxidation steps that convert the alcohol group to an aldehyde group and then to an acid group. The final product, N-isopropylterephthalamic acid, can be quantified using gas chromatography with electron capture detection or high performance liquid chromatography with fluorescence detection. These techniques can be used for monitoring human exposure to this metabolite.

Versatile small molecule scaffold

6-(Trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione is a potent inhibitor of tumor cell growth. It inhibits the stepwise oxidation of 4-chloro-5-methylisatin to 4-chloroimidazole. 6-(Trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione is an analog of the antitumor agent 5-(trifluoromethyl)isatin. The reaction mechanism involves the formation of an iminium ion that undergoes a condensation with a thiophene and subsequent bromination. This forms an intermediate that can be isolated and identified as 6-(trifluoromethyl)-N-[(6'-bromohexyl)oxy]-2,4'-d

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4,4²-Diaminobenzanilide is a molecule that contains an amide group. It undergoes hydrogen bonding interactions with sodium carbonate and biphenyl. The thermal expansion coefficient of 4,4²-diaminobenzanilide is 1.5 x 10^5 K/mol. This substance has a molecular weight of 218.2 grams per mole and a density of 1.08 grams per cubic centimeter. The solubility of 4,4²-diaminobenzanilide in water at 20 degrees Celsius is 3.2 grams per 100 milliliters, and it does not dissolve in hydrochloric acid or water vapor at 20 degrees Celsius. The proton NMR spectroscopic data for this compound show the presence of hydroxyl groups and carbonyl groups in addition to the amine group found in the molecule's structure. FTIR spectroscopy confirms the presence of these functional groups as well

Diethyl 1,4-cyclohexanedione-2,5-dicarboxylate is a polyester that is produced by the alkylation of diethylene glycol with terephthalic acid. It has been shown to have anti-cholinesterase activity in clinical studies and has been used as a pharmaceutical intermediate. This compound is also found in Huperzia serrata, which is an herbal medicine used to treat Alzheimer's disease. Diethyl 1,4-cyclohexanedione-2,5-dicarboxylate can be found in lycopodium alkaloid and terpenes. It binds to carboxyalkyl groups in proteins, inhibiting protein synthesis. Diethyl 1,4-cyclohexanedione-2,5-dicarboxylate has a strong anion radical and reacts with methoxy groups on proteins. This reaction leads to the formation of

Ameltolide is a chemical compound that belongs to the class of tricyclic diterpenes. It has been shown to have a variety of biological activities, including anticancer, immunosuppressive, and anti-inflammatory properties. Ameltolide has been shown to inhibit the activity of the N-methyl-D-aspartate (NMDA) receptor by hydrogen bond formation with the channel at the NMDA binding site. In vivo studies have demonstrated that ameltolide has an effect on cognitive function when administered at high doses. Ameltolide also inhibits voltage-gated Na+ channels, which are responsible for action potential generation in neurons and muscle cells. This inhibition leads to a decrease in nerve conduction velocity and an increase in duration of muscle contraction, resulting in increased fatigue.