Building Blocks

Versatile small molecule scaffold

1,3-Di-tert-butyl cyclohexane-1,3-dicarboxylate is a fluorescent probe that senses metal cations. The fluorescence of 1,3-Di-tert-butyl cyclohexane-1,3-dicarboxylate changes in response to changes in the concentration of monovalent and divalent metal cations. This probe can be used to detect the presence of cations in various types of samples such as organic solvents and water. The probe’s fluorescence is proportional to the concentration of metal ions present, with a linear relationship between the change in fluorescence intensity and the change in ion concentration.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Allylhydrazine is a chemical compound that is used as an inhibitor of cellular kinases. It has been shown to inhibit the growth of colon and prostate cancer cells, as well as breast and lung cancer cells. Allylhydrazine is a disubstituted imidazole with two amino groups and one hydrazine group. This product also inhibits angiogenesis and has been shown to prevent the formation of new blood vessels in solid tumors. Allylhydrazine has been synthesized from allyl alcohol in the presence of acidified hydrogen chloride gas, providing a yield of about 50%.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Benzyloxy)-1-propanol (2-BP) is a glycidol derivative that can be used to produce propanol. 2-BP reacts with Tenofovir, an antiviral drug, in the presence of enolate and organometallic catalysts to form acetaldehyde. 2-BP also reacts with chloride to form alkoxides, which are useful in the synthesis of adenine derivatives. In addition, 2-BP has been shown to react with vinyl ethers and alcohols in the presence of catalysis to form benzyl derivatives.

Ethyl 5-oxoheptanoate is a clear, colorless liquid that can be synthesized by reacting benzene with acetone. The synthesis of ethyl 5-oxoheptanoate is an example of a Friedel-Crafts reaction. This chemical is soluble in organic solvents such as acetone and cyclohexane and has low toxicity. It can be used as a reagent for the preparation of esters from alcohols, phenols, or carboxylic acids. Ethyl 5-oxoheptanoate can also be used to prepare resorcinol, which is a precursor to polymers and dyes, by hydrogenation of the molecule. Preparative methods are often used to produce this product because it has limited solubility in water.

Aureusimine A is a natural product that has been identified as a potential biomarker for Staphylococcus aureus. This molecule is produced by the bacterial species Aureobasidium pullulans and has been shown to have antibacterial, antifungal, and antiparasitic properties. The molecule also inhibits protease activity in Staphylococcus strains and prevents the growth of bacteria. It is also a potential therapeutic agent for the treatment of staphylococcal infections.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold