Building Blocks

<p>Versatile small molecule scaffold</p>

<p>6-Hydrazinylpyridine-3-carboxamide is a coligand with high affinity for technetium, which is used in analytical chemistry. The compound has been shown to bind to the transcription-polymerase chain reaction (PCR) and monoclonal antibody binding sites of the human immunodeficiency virus type 1 (HIV-1). 6-Hydrazinylpyridine-3-carboxamide has also been shown to be an effective inhibitor of protein synthesis in animal cells and to inhibit tumor cell growth. Clinical trials have demonstrated that this compound can be used as an aneurysm sealant and as a cancer treatment.</p>

<p>3-Oxo-3-(3-thienyl)propanenitrile is a metabolite of 3-oxothiopropanal. It is an analog of prostaglandin, which has been shown to have antiinflammatory properties. 3-Oxo-3-(3-thienyl)propanenitrile has been used in the treatment of adjuvant arthritis and was found to inhibit the production of prostaglandins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Ethylamino)benzaldehyde (2-EABA) is a reactive, radiation-sensitive compound that can be used as a diagnostic agent. 2-EABA is the precursor of styryl dyes and coumarin derivatives. 2-EABA reacts with chloride to form an amide in the presence of hydroxyl groups. The amide reacts with aromatic hydrocarbons to produce cationic polymers. The reactive functional group of 2-EABA is an aldehyde group, which reacts with basic dyes to form diamines and diamides. In addition, it has been shown that 2-EABA can be used to detect chloride ions in water samples, owing to its high solubility in water.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>3-Phenoxycyclobutan-1-one is a chemical compound that belongs to the group of sulfoxides. It is an intermediate in the synthesis of other compounds, such as methyl esters and sulfones. 3-Phenoxycyclobutan-1-one can be synthesized by coupling with phenol and cyclohexanone in the presence of a base. 3-Phenoxycyclobutan-1-one is also a precursor for the synthesis of other compounds, such as dyes and pharmaceuticals. The conversion to 3-phenoxycyclobutanones requires pyrolysis at temperatures greater than 300°C.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>3-Methoxy-2,5-furandione is a reactive functional group that belongs to the group of β-carboline alkaloids. It is used as a crosslinker in polyvinyl and iontophoresis applications, as well as a cross-linking agent for coatings or natural compounds. 3-Methoxy-2,5-furandione reacts with benzyl groups to form crosslinked products that are stable in acidic environments. This product is also used as an intermediate for the synthesis of tetronic acid (a coating) or reaction products.</p>

<p>2-Chloro-6-(2-methylpropyl)pyridine-3-carbonitrile is a naphthyridine that has been correlated to the ionization of the molecule. The substituent on the nitrogen atom is not ionized, while the nitrogens on the ring are. This difference in ionization constants allows 2CMP to be used as a research tool for studying nucleic acids and proteins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>