Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Vinylnicotinic acid methyl ester belongs to the group of antimicrobial agents. It is a chemical compound that has been shown to be effective against cervical cancer and may have potential as an anticancer drug. 5-Vinylnicotinic acid methyl ester inhibits the growth of human chorionic gonadotropin (HCG) in women, which is a hormone necessary for ovulation and pregnancy. This compound also inhibits the growth of viruses, such as herpes simplex virus type 1 (HSV-1), and bacteria, such as dittrichia sp., which causes inflammation of the throat. 5-Vinylnicotinic acid methyl ester has also been shown to inhibit protein synthesis in human osteosarcoma cells at low concentrations, but not at high concentrations.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Formyl-3-hydroxynaphthalene-2-carboxylic acid (4FHN) is an antibacterial agent. It is bacteriostatic and has been shown to be effective against gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa, but not against gram-positive bacteria such as Staphylococcus aureus. 4FHN was found to inhibit the growth of both gram-positive and gram-negative bacteria by binding to the ribosomal RNA in the bacterial cell wall, thereby inhibiting protein synthesis and cell division. 4FHN also shows antimicrobial activity due to its ability to form stable hydrazones with nucleophilic centers in the bacterial cell wall. These compounds react with cellular macromolecules, leading to cell death.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Phenylpyrazolidin-3-one is a pyrazole compound that has a tautomeric form. It has been shown to selectively interact with anions, such as chloride anion, in the presence of hydrogen bonds. This leads to the production of a hydrogen cation and an electrophilic imine. 5-Phenylpyrazolidin-3-one is used in chemosensors for the detection of various chemicals, including formaldehyde and acetaldehyde. 5-Phenylpyrazolidin-3-one also has antitumor activity due to its ability to inhibit DNA synthesis and induce apoptosis in cancer cells.</p>

<p>Versatile small molecule scaffold</p>