Building Blocks

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>3-Phenyl-morpholine is a functionalized aliphatic amine with three stereocenters. It is used as a substrate for the synthesis of cyclic and acyclic compounds. 3-Phenyl-morpholine can be used to functionalize amines, oximes, and other substrates with excellent diastereoselectivity and operational efficiency.</p>

<p>Methyl 2-acetylpyridine-4-carboxylate is a photocurrent generating compound that can be used in organic solar cells. It has been shown to enhance the performance of organic solar cells by acting as a bidentate ligand for ruthenium complexes. Methyl 2-acetylpyridine-4-carboxylate is synthesized from the diacid, acetylene and formaldehyde. It can be used as an electron acceptor in coordination chemistry involving anthracene to produce a Ru(II) complex. The electron donor is usually a metal ion such as ruthenium, which can be activated by light or heat to generate electrons.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(R)-3-Amino-1-phenyl-propan-1-ol is an antidepressant drug that belongs to the class of chiral, enantioselective reductants. It has been shown to have a high enantioselectivity for the reduction of nitroarenes and sulfides. The catalyzed reduction of these substrates is based on the formation of an intermediate sulfide complex with borane, which is then reduced by (R)-3-Amino-1-phenyl-propan-1-ol. The method described here can be used for the synthesis of alcohols and nitriles from optically pure starting materials.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Chromoionophore xi (CI) is a monoclonal antibody that binds to the CCR5 receptor on the surface of HIV-1. The binding of CI to the receptor inhibits HIV-1 entry into CD4+ cells, leading to a decrease in viral load. CI has an effective dose of 0.8 μg/mL and inhibits HIV-1 infection by 50% at 1 μg/mL. Chromoionophore xi has been shown to be effective in inhibiting HIV-1 infection in vitro and in vivo in mice.</p>

<p>(E)-3-(3-(Benzyloxy)phenyl)acrylic acid is a chiral, synthetic acrylic acid that is used in the synthesis of enantiomerically pure (2S,4R)-tapentadol. This compound is prepared by an enantioselective alkylation of (2S,4R)-2-aminobenzoic acid with benzyl bromide. The preparation of this compound was achieved by a chromatographic method and the purified product was obtained as a white solid. The purity of the product was confirmed by HPLC analysis and mass spectrometry.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold