Building Blocks

4-Amino-4-oxobutanoic acid is a weak organic acid that is found in the form of a white, crystalline powder. It has a molecular weight of 123.17 and a melting point of 163°C. 4-Amino-4-oxobutanoic acid is soluble in water, but not in alcohols or ethers. This compound can be classified as an amide, due to the presence of hydrogen bonds between the carbonyl group and the amino group. 4-Amino-4-oxobutanoic acid is also known as 4-[(3-chlorophenyl)amino]-4-oxobutanoic acid (CLAB).

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Cyanobenzotriazole is a labile and reactive compound that has been used as a reagent in organic synthesis, due to its nucleophilic properties. 1-Cyanobenzotriazole can be used in the elimination reactions of amines or as a coupling agent for the formation of nitriles from terminal alkynes. The compound has been used as an analytical method for measuring the concentration of protein, nucleic acid and peptide bonds. 1-Cyanobenzotriazole is also used in the preparation of biomolecules such as proteins, peptides, and oligosaccharides.

Versatile small molecule scaffold

2-Phenylcyclopentan-1-amine is a reconstituted drug that belongs to the group of amines. It is used for the treatment of inflammatory bowel disease, and is also an anti-epileptic drug. 2-Phenylcyclopentan-1-amine has been shown to inhibit mast cell activation and histamine release in rats with experimental colitis. This drug may be effective for the treatment of allergic diseases such as asthma, urticaria, and eczema.

2-(Trimethylsilyl)phenol is an inorganic compound that is used as a reagent to cleave bonds, which can be achieved by the addition of sodium sulfide or ultrasonic extraction. It also reacts with o-glycosylations and fatty acids. 2-(Trimethylsilyl)phenol is used to prepare samples for analysis by gas chromatography, mass spectrometry, or nuclear magnetic resonance spectroscopy.
2- (Trimethylsilyl)phenol is an analytical method that has been developed for the determination of chloride in water samples. This method is based on the protonation of chloride ions followed by bond cleavage reactions with protonated trimethylsilyl phenols and sodium sulfide. The reaction products are then analyzed using gas chromatography or infrared spectroscopy.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

(e)-2-Methyl-3-phenylacrylaldehyde (E2PAA) is a tyrosinase inhibitor that has been shown to inhibit the production of melanin in vitro using human skin cells. E2PAA has been immobilized on magnesium oxide, which prevents it from being washed away by the buffer solution and allows for its use as a reusable catalyst. The uptake of E2PAA was found to be higher when compared to other compounds, such as cis-ddp (1,4-dihydroxynaphthalene), due to its hydrophobic nature. The molecular electrostatic potentials have been calculated for both cis-ddp and E2PAA, which showed that E2PAA has a slightly lower value than cis-ddp. These results indicate that E2PAA is more lipophilic than cis-ddp, which may explain its higher uptake in the skin cells. Structural studies have also

Versatile small molecule scaffold

Versatile small molecule scaffold