Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Fluoro-2-iodobenzaldehyde is a chemical used in the synthesis of other compounds. It can be used to synthesize hydrochlorides and condensation products with amines, amidines, and quinazolines. The yields of these reactions are high. 4-Fluoro-2-iodobenzaldehyde can also be used to make 2,6-diaminoquinazoline from 2,4,5-trichlorophenylacetonitrile.

Versatile small molecule scaffold

Ethyl 2-(2-bromophenoxy)acetate is an organic compound that is used as a reagent in organic synthesis. The cell parameters of ethyl 2-(2-bromophenoxy)acetate anhydrous are:

4-(2-bromophenyl)butanoic acid is a ligand that has been used in intramolecular cyclisation reactions. It is also an amidation reagent, which can be used to synthesise amides from carboxylic acids and ammonia. 4-(2-bromophenyl)butanoic acid undergoes an amidation reaction with aromatic amines in the presence of a base to form 4-(2-bromophenyl)butanamide. This product has been used as an intermediate for the synthesis of other compounds such as aziridines and oxazolidinones.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(Methoxymethoxy)benzoic acid (MMBA) is a synthetic compound that is used in the synthesis of allyl compounds. MMBA is not chemically reactive and does not undergo any reactions at room temperature. This substance can be activated by adding a nucleophile, such as an alcohol or water molecule, which will then react with the electrophilic carbon atom. This reaction produces epoxide and an alkene product. The most common reaction occurs with methanol, producing methoxypropane, which can then be converted to other organic compounds. Research has shown that MMBA has anticancer properties due to its ability to inhibit cell growth and induce apoptosis in humans.

Versatile small molecule scaffold

Trimethyl(trichloromethyl)silane is a chlorinating agent that reacts with hydrocarbons to form quinones. It is synthesized in the liquid phase and reacts with aldehydes, amines, and sodium formate to produce the trichloromethylated product. Trimethyl(trichloromethyl)silane is activated by electron deficiency and can be used to circumvent functional groups such as hydroxyl or carbonyl. This chemical also has properties that are not shared by other chlorinating agents, such as its ability to react with hydrogen fluoride without forming hydrochloric acid.

Versatile small molecule scaffold

3-Ethylpentanoic acid is a fatty acid that is naturally found in the human body and can be synthesized by the body from other fatty acids. 3-Ethylpentanoic acid has been shown to inhibit histone deacetylase (HDAC) activity, which may be a possible mechanism for its antitumor effects. HDAC inhibitors are being studied as potential anticancer drugs. 3-Ethylpentanoic acid also inhibits the enzymatic activity of fatty acid synthase, thereby preventing the production of branched-chain fatty acids that are toxic to the liver. In addition, 3-ethylpentanoic acid has been shown to have pharmacokinetic properties in rats and mice with high levels of enzymes that convert it into a more hydrophobic form, which may lead to better absorption from the gastrointestinal tract and decreased metabolism by enzymes in the liver.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-(Pyridin-3-yl)butane-1,3-dione is an activating agent that can be used to treat a variety of disorders. It activates the insulin receptor and has been shown to activate the PPAR alpha and gamma heterodimers in vitro. 1-(Pyridin-3-yl)butane-1,3-dione may also have a proliferating effect on cells. This compound is a chelate ring that contains heterocyclic bonds, which are often found in compounds with profiles similar to those of 1-(pyridin-3-yl)butane-1,3-dione. The structural formula for this compound is shown below:

Versatile small molecule scaffold

11-Aminoundecan-1-ol is a bifunctional molecule that binds to the receptor and stabilizes it. It can be used as an antimicrobial agent against human pathogens, such as HIV, by preventing the virus from attaching to cells. 11-Aminoundecan-1-ol also has activity against plant viruses. This compound is an anhydroglucose with hydroxamic acid groups that are responsible for its antiviral properties and also contains a particle with azide functionalities. 11-Aminoundecan-1-ol has shown efficacy in inhibiting the replication of human Herpes simplex virus types 1 and 2 (HSV) in vitro, which may be due to its ability to bind to the HSV glycoprotein B envelope protein GP2.
11-Aminoundecan-1-ol can also bind to the receptor lysine and stabilize it. This binding prevents azides from reacting with l

Versatile small molecule scaffold

Versatile small molecule scaffold

Piperazine-1-sulfonamide is a protein inhibitor that belongs to the group of regulatory agents. It is used to regulate the growth of various types of cells, including immune cells and smooth muscle cells. Piperazine-1-sulfonamide has been shown to inhibit chemokine receptor activity in inflammatory bowel disease, which may be due to its ability to inhibit CXCR4 and CCR5 receptors. This drug also inhibits dpp-iv, an enzyme involved in protein degradation. The pharmacokinetic properties of this agent are not well studied, but it does show toxicity studies in rats at higher doses. Piperazine-1-sulfonamide can cause congestive heart failure and liver damage at high doses, so it should not be used for prolonged periods of time.

2,2'-Bifuran is a synthetic compound with a carbonyl group and fluoro substituents. The carbonyl group of 2,2'-bifuran participates in reversible oxidation reactions with the cationic polymerization initiator, which leads to the formation of polymers. The presence of fluoro substituents on the bifuran ring is important for these reactions because they allow for steric interactions with neighboring groups during polymerization. This reaction is highly scalable due to the simple synthesis and inexpensive reagents needed to produce it. 2,2'-Bifuran has been used as an initiator in diagnostic tests and as a structural formula for other compounds.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4,5,6,7-Tetrahydro-benzo[d]isoxazol-3-ol (THI) is a chromatic integrating device that utilizes an algorithm and coding to update circuitry and devices. THI interacts with the optical vector techniques in order to position itself. The circuitry updates in response to the interaction with the optical vector techniques. THI can be utilized for many purposes such as updating bandwidth, devices, or interaction.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Iododibenzofuran is a fluorescent compound that has been used as a probe for the study of neutral endopeptidase activity. The compound is characterized by a high degree of thermal stability and an inhibitory potency at pH 7.0 that is approximately 3 orders of magnitude greater than that of the active site inhibitor, anthracene. 3-Iododibenzofuran can be synthesized using chemoenzymatic methods, with efficiencies and profiles that are similar to those obtained in the conventional method. This probe can also be used to investigate the functional role of proteins in living cells or tissues.
3-Iodobenzofuran has been shown to have pressor effects in rats and can cause tetrazole (a type of explosive) to detonate when heated, which makes it unsuitable for use in devices such as explosives or pyrotechnics.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Ethynylcyclohexan-1-ol is a cyclohexanol derivative that is synthesized by the intramolecular coupling of two phenylsulfonyl acetates. It has been shown to be an acid and base conjugate. 2-Ethynylcyclohexan-1-ol has a photophysical profile that includes fluorescence, which makes it useful for detection. This compound also yields ketones and carbocycles, making it useful in synthesis.

3-Aminoquinolin-2(1H)-one is a synthetic compound. It has been prepared by condensation of 2-aminoacrylic acid with 1,3-diaminopropane. This reaction yields an imine that can be hydrolyzed to the corresponding amine. 3-Aminoquinolin-2(1H)-one has been used as an efficient method for the synthesis of hippuric acid and its isomers. The spectra of 3-aminoquinolin-2(1H)-one show three peaks at m/z=193, 182 and 144, which correspond to the molecular ion peak (m/z=193), the corresponding methylene peak (m/z=182) and the protonated amine peak (m/z=144). The mass spectrum shows two major peaks: one at m/z=193 and one at m/z=145. These peaks are due to fragmentation

Versatile small molecule scaffold

3-Sulfanylbenzamide is an herbicide that inhibits the growth of plants by inhibiting the production of chlorophyll. It is a halogen that binds to cycloalkyl, which prevents the formation of phenylalanine, leading to cell death. 3-Sulfanylbenzamide has been shown to be effective in controlling the growth of weeds such as lambsquarters and ragweed.

Versatile small molecule scaffold

Versatile small molecule scaffold

The herbicide 3-Hydroxy-2-phenylcyclopent-2-en-1-one is a phenoxy compound that inhibits the enzyme acetolactate synthase, which is required for the biosynthesis of branched chain amino acids. This inhibition leads to a shortage of these amino acids and growth inhibition in plants.

2-Bromopropan-2-yl)benzene is an impurity in the production of polypropylene. It is a potential monomer that can be used for the synthesis of polymers. The compound has been shown to have copolymerization properties and can be used as a debrominating agent for poly(vinyl chloride). 2-Bromopropan-2-yl)benzene's reaction mechanism is based on the addition of bromine to the double bond of an organic compound. The product of this reaction is a halide, which is then hydrolyzed to release water and hydrogen bromide gas. 2-Bromopropan-2-yl)benzene also has antiinflammatory properties and has been shown to inhibit the production of chloride ions in immune cells. 2-Bromopropan-2-yl)benzene has also been shown to have peroxide decomposition properties, which may cause

Versatile small molecule scaffold

Ethyl cyclobutylideneacetate is a compound that is used as an intermediate in the synthesis of pyrimidine compounds. It has autophagy-inducing activity and can stimulate the growth of epidermal cells. This compound has not been shown to have any direct effects on kinases, but it is known to act as a modulator for factors such as epidermal growth factor, which can regulate cell proliferation. Ethyl cyclobutylideneacetate is active in the presence of solvates and regulators. The tautomers of this compound are stereoisomers that are also homologues, with some polymorphs possible depending on the solvent conditions.

3-Methyl-2-nitrobenzaldehyde is a compound that has been shown to undergo the shift reaction in which one atom or group of atoms is moved from one position to another. This reaction was catalyzed by carbodiimides, and the product was an n-substituted carbodiimide. 3-Methyl-2-nitrobenzaldehyde also has been shown to react with methylamine as well as amines such as aniline, cyclohexylamine, and benzylamine. The reaction products are diarylmethane derivatives with a nitrogen atom and an aryl group.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Phenylquinolin-4-amine is a ligand that binds to the active site of the human apoE4 protein, which is involved in lipid metabolism. 2-Phenylquinolin-4-amine has been shown to be cytotoxic against cancer cell lines and potent at low concentrations. It was also shown to have potent activity in apoptosis induction and cell cycle arrest. This ligand interacts with amide groups on the surface of proteins and can form amide bonds with other molecules, including formamide and solvents. The binding constants for 2-phenylquinolin-4-amine have been measured using molecular modeling techniques and bioinformatics databases.

2-(2-Bromoethoxy)-2-methylpropane is a cavity solvent that is used to extract fullerenes, metal ions, and other organic compounds from crystals. It can be used as an extractant for metal cations in the presence of water. 2-(2-Bromoethoxy)-2-methylpropane has been shown to have ion channel inhibition properties. This compound will bind to the hydrophobic cavities of ion channels, which prevents the flow of ions through the channel. This binding leads to a decrease in membrane potential and causes cells to become unstable or die. 2-(2-Bromoethoxy)-2-methylpropane crystallizes in the monoclinic crystal system with a space group P21/c. In this crystal structure, there are two molecules per unit cell with their molecular axes parallel to each other and perpendicular to the two mirror planes that intersect at 90° angles. The conformation of this molecule can

Versatile small molecule scaffold

1-Nitro-4-propoxybenzene is a covalent inhibitor of aspartic acid proteases. It is an aspartic acid analog that competes with the natural substrate for the active site and inhibits the transpeptidation reaction. This compound has been shown to be highly selective against renin, which is a key enzyme in the blood coagulation cascade. The 1-nitro group can be replaced by other groups to modulate potency or selectivity. These modifications may also improve water solubility, stability, or bioavailability.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold