Building Blocks

<p>Versatile small molecule scaffold</p>

<p>4-Phenyl-1H-indole is a heterocyclic organic compound that is structurally related to pyrazoles, indazoles, and other cyclic compounds. It has the chemical formula CHN and it can be found in yields of 0.2% by weight. Substituents on the 4-phenyl ring include carboxyl and cyclic structures. Reactions that can be carried out on this compound include a Diels-Alder reaction with maleic anhydride to form a heteroleptic compound. The functional group present in this molecule is the carboxylate ester.</p>

<p>3-Chloropropane-1-sulfonamide is a nonabsorbable heterocyclic sulfonamide that inhibits the permeability of pyrimidines and alkenes. It is synthesized by reacting an isocyanate with a template molecule. The synthesis of 3-chloropropane-1-sulfonamide involves the reaction of an isocyanate with a pyridine or a template molecule such as 3,5-dimethoxybenzene or 2,6-diisopropylphenol. This compound can be used as an inhibitor for the synthesis of bicyclic heterocycles, such as indole and quinoline.</p>

<p>2-hydroxy-4-pyrrol-1-yl-benzoic acid (HPABA) is a postulated structure-based drug that has been shown to inhibit the bacterial enzyme, 2,4-diaminopyrimidine deaminase (DAP). HPABA is an amide and analog of the natural substrate of DAP. It inhibits DAP by competitive inhibition at the active site. The dose of HPABA required for inhibition is dependent on the concentration of DAP in the cell. The low molecular weight and lipophilic properties of HPABA allow it to cross cellular membranes easily. This compound also has pharmacokinetic properties that make it an ideal candidate for use as a chemotherapeutic agent. HPABA is metabolized into reactive intermediates by cytochrome P450 enzymes and glutathione S transferases, which have been shown to cause DNA damage and cytotoxicity in cancer cells. These metabolites are further metabol</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methyl-2,3-dihydro-1H-inden-2-one is a piperidine that belongs to the class of nitro compounds. It has been shown to be statistically significant in animal trials for the treatment of melanogaster and cicer arietinum. 1-Methyl-2,3-dihydro-1H-inden-2-one has also been evaluated as an antihyperglycemic drug in women and infants. The molecule contains two nitro groups, which increase its solubility in water and allow it to be administered orally. This drug is metabolized into an oxindole, which inhibits the enzyme dihydropyrimidine dehydrogenase, thereby preventing DNA synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenoxynicotinic acid is a drug that inhibits the activity of nitric oxide synthase, an enzyme involved in the production of nitric oxide. Nitric oxide is a gas that is produced by macrophages and other cells in response to inflammation or injury. It has been shown that 2-Phenoxynicotinic acid inhibits the production of nitric oxide in vitro. This drug has been used clinically to treat cardiovascular disorders and diseases, including arrhythmias, hypertension, angina pectoris, and coronary artery disease. 2-Phenoxynicotinic acid has also been shown to be effective against leishmania parasites. It binds to glutathione s-transferase, an enzyme that is found on the surface of cells and plays an important role in cellular detoxification processes. The binding of 2-Phenoxynicotinic acid with glutathione s-transferase leads to inhibition of this enzyme's enzym</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Methylsulfamoyl)benzoic acid (MSBA) is a nitro compound that inhibits cancer cell growth by binding to the DNA of cancer cells. It is also an inhibitor that binds to the enzyme cyclin-dependent kinase 2, which is involved in cell division. 3-(Methylsulfamoyl)benzoic acid has been shown to inhibit the growth of cancer cells in culture and inhibits tumor formation in mice, but it does not have any effect on normal cells. The mechanism of action may be due to its ability to inhibit the production of amines, which are necessary for the synthesis of DNA and RNA.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2-Methoxyethoxy)propanenitrile is a complex molecule that can be synthesized in an efficient method. It is used as a chemical catalyst to promote reactions involving pyrrole and other heterocycles, such as cross-coupling reactions with aryl chlorides. 3-(2-Methoxyethoxy)propanenitrile has been shown to form monolayers on the surface of electrodes, which may be useful for the fabrication of devices. The solvents used in this synthesis are also important for the design of new synthetic methods.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Quinolin-4-amine hydrochloride is a DNA polymerase inhibitor. It inhibits the transcription of viral genes by binding to the DNA polymerase enzyme, thereby preventing transcription and replication of viral DNA. Quinolin-4-amine hydrochloride has shown to be effective against various viruses in tissue culture, including herpes simplex virus, vaccinia virus, and HIV. The compound has also been shown to inhibit the growth of influenza A virus in cell culture. Quinolin-4-amine hydrochloride is useful as a diagnostic agent for identifying unvaccinated individuals who are at risk for acquiring certain viruses or as an antiviral agent in tissue culture or cell culture during outbreaks of virulent viruses such as HIV or hepatitis C virus.</p>

<p>Versatile small molecule scaffold</p>

<p>Fmoc-DL-alanine is a moiety that is used in the synthesis of peptides and proteins. It has a pyrrole ring with an imidazole side chain. It is fluorescent, which can be useful for spectral analysis. Fmoc-DL-alanine has been shown to be a potent inhibitor of malignant cells, which may be due to its ability to inhibit the enzyme amino function. Fmoc-DL-alanine is stable under acidic conditions and does not react with nitro groups or carbohydrates. This compound is also soluble in water and can be synthesized with optimized acid residues.</p>

<p>2-Formyl-5-phenylphenol is an analytical reagent that can be used as a probe for detection of zinc ions in aqueous solutions. It is synthesized from salicylaldehyde and phenylmagnesium bromide with zinc chloride as a catalyst. 2-Formyl-5-phenylphenol reacts with the hydroxide ion to form an alcohol, which is then oxidized by hydrogen peroxide to form a phenoxy radical. This radical reacts with another molecule of hydrogen peroxide to form a fluorescent compound, homolytically cleaving the molecule. The reactivity of the heterocyclic ring depends on its position on the ring, with meta positions being more reactive than ortho or para positions.<br>2-Formyl-5-phenylphenol has been shown to have good reactivity with other nucleophiles such as amines, thiols, alcohols, and carboxylic acids.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methylcycloheptane-1-carboxylic acid is a benzyl benzoate compound that has antipsychotic properties. It is used as an antipsychotic agent and also has a tolerability profile with minimal side effects. The drug binds to the dopamine D2 receptor, resulting in increased uptake of dopamine in the synapse by blocking its reuptake. The compound is soluble in water and lipid solvents, which allows for it to be absorbed easily through the skin or mucous membranes. 1-Methylcycloheptane-1-carboxylic acid is not active against bacteria and fungi.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>P-Tolylacetyl chloride is a benzyl compound that has potent cytotoxicity. It is used in the synthesis of phenylacetates, which are intermediates for the synthesis of various pharmaceuticals. P-Tolylacetyl chloride has been shown to induce apoptosis in human cancer cells, including HCT116 and other tumor cell lines. This agent also induces DNA fragmentation and inhibits protein synthesis by inhibiting translation initiation factors. P-Tolylacetyl chloride also has an antitumor effect by inhibiting tumor growth in mice with subcutaneous leukemia. It is thought that this effect may be due to its ability to inhibit the production of reactive oxygen species (ROS) and reduce levels of intracellular glutathione.</p>

<p>2-Chloro-3-hydroxyquinoxaline is a chemical compound that belongs to the group of nitrones. It can be synthesized from 2,4,6-trichloro-1,3,5-triazine and amines. The yields are quite high with a range of 60%-90%. 2-Chloro-3-hydroxyquinoxaline can be used as a starting material for the synthesis of substituted quinoxalinones by coupling with nitro compounds or halides.<br>2-Chloro-3-hydroxyquinoxaline has been found to have pharmacological effects on biological systems in x ray analysis. It is also used in the synthesis of annulated quinoxalinones.</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 5-Hydroxy-1-methyl-4-nitroimidazole sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Methyl-1,2,3,4-tetrahydroisoquinolin-1-one (3MTI) is a chemical compound that has been synthesized for the first time. This molecule has been studied experimentally in the optical properties of its spectrum and reactivity. 3MTI has been shown to react with hydrogen peroxide to produce water and formaldehyde. The reaction mechanism is based on the theory that 3MTI is an electron donor and hydrogen peroxide is an electron acceptor. The reaction process occurs by photosensitization of the molecule with UV light or visible light. The reaction system involves the direct oxidation of 3MTI by molecular oxygen in presence of hydrogen peroxide to produce water and formaldehyde.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate is a chemical compound that belongs to the group of organic compounds. It is a colorless liquid with a pungent odor and a boiling point of 150 degrees Celsius. It is soluble in water, ethanol, and ether. Ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate can be used as an amine transfer agent and has been shown to react with hydroxyl ions under acidic conditions. The reaction rate increases when the concentration of acid solutions increase. This chemical also reacts with inorganic anions to form salts.</p>

<p>1-(2,4-Dimethoxyphenyl)-2-thiourea is a lead compound for the development of opioid analgesics. It has shown to be an effective analgesic in animal models and has been found to have low side effects. This drug interacts with the μ-opioid receptor and activates it by changing its conformation. This activation mechanism is different from that of other opioids, which typically inhibit the receptor's activity. The activation mechanism of 1-(2,4-dimethoxyphenyl)-2-thiourea is believed to be due to structural modifications at the site of the receptor that promote signal transduction. This drug also acts as a competitive antagonist at the μ-opioid receptor, which may contribute to its antinociceptive properties.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Nitro-1,3-benzoxazole-2-carbonitrile is a chemical compound that inhibits the uptake of drugs into cells. It is a selective inhibitor of the enzyme adenosine transporter (AT) which prevents the uptake of adenosine and other compounds into cells. The inhibition is reversible under conditions where ATP levels are low. 5-Nitro-1,3-benzoxazole-2-carbonitrile has been shown to be stable when exposed to human serum and can be used for sample preparation prior to analysis with high performance liquid chromatography (HPLC). This agent has also been shown to inhibit theophylline uptake in human erythrocytes, making it a useful tool for studying drug interactions. 5NBB also inhibits caffeine uptake in microspheres and can be used as an analytical reagent for determining caffeine content in beverages.</p>

<p>1-Methylnaphthalene-2-carbaldehyde is a compound that can be found in acetonitrile. The molecule has two isomers, which are distinguished by the position of the methyl group on the ring. The 1-methylnaphthalene-2-carbaldehyde molecule is an organic compound with a molecular weight of 136.19 g/mol and a boiling point of 141°C at 0.1 mmHg. It has a photoisomerization quantum yield of 0.05 and fluorescence lifetimes of 4 to 5 nanoseconds, which are both relatively low. The molecule's singlet state lifetime is about half that of its triplet state lifetime, although it has been shown to have a higher quantum yield for this state than for its ground state. This means that the singlet state is more stable than the ground state, so it will remain in this state longer before emitting light or changing back to its ground state. This property makes</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Benzylphenylmethanol is a natural compound that belongs to the class of amines. It is found in pyrethrum, which is derived from plants of the genus Chrysanthemum. 4-Benzylphenylmethanol has been used as a supplement for insect control, usually as an additive to natural pyrethrins. This substance has been shown to be effective against insect species such as the German cockroach, the fruit fly, and the mosquito. 4-Benzylphenylmethanol also has insecticidal properties by preventing insects from breaking down the chemical bonds in their cell membranes. This allows for more rapid death of insects and lessens their ability to regenerate cells after contact with this substance.</p>

<p>7-Chloroquinoline-4-carbaldehyde is an intermediate in the synthesis of quinolines. It is a functionalized, hydroxylated compound that can be used as an antiproliferative reagent. 7-Chloroquinoline-4-carbaldehyde has been shown to inhibit the growth of leukemia cells, prostate cancer cells and breast cancer cells. The hydroxyl group on this molecule reacts with electrophiles to form covalent adducts and undergoes substitution reactions with amino groups. This molecule also has an aryl group that can be modified to create bioisosteres.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Bis(propan-2-yl) [(4-methylbenzenesulfonyl)oxy]methanephosphonate is a nucleoside phosphonate that inhibits the replication of dna and RNA viruses. It is used to treat human immunodeficiency virus (HIV), varicella, and hepatitis. The antiviral activity of bis(propan-2-yl) [(4-methylbenzenesulfonyl)oxy]methanephosphonate has been shown to be effective against HIV, herpes simplex virus type 1, and hepatitis B virus. This drug binds to the viral nucleic acid polymerase and prevents it from adding new nucleotides to the growing strand of DNA or RNA.</p>

<p>Versatile small molecule scaffold</p>

<p>2,4-Dibromo-5-methoxyaniline is an analog of 2,4-diaminopyridine. It is a synthetic compound that can be prepared by catalytic reduction of the corresponding bromide. The yields are between 60 and 90%. It is used as a precursor to make other compounds such as methoxybenzene and 4-bromo-2,6-dimethoxyphenol. The compound has two methoxy groups and two hydroxy groups that can be substituted with dialkoxy or alkoxy groups. This compound also undergoes debromination to form 2,4-dibromo-5-(hydroxymethyl)aniline. 2,4-Dibromo-5-(hydroxymethyl)aniline can be oxidized to form aniline or reduced to form dihydroxybenzene (1,3).</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3-methylquinoline is a pyrimidine compound that has been shown to have anti-inflammatory properties. It has been demonstrated to inhibit the conversion of propionate and acetyl-CoA into propionyl CoA, which is an important step in the synthesis of fatty acids. This inhibition leads to a decrease in the production of inflammatory leukotrienes and prostaglandins. 2-Bromo-3-methylquinoline also inhibits the formation of reactive oxygen species by inhibiting the conversion of isobutyrate into isobutyraldehyde, which results in decreased inflammation and oxidative stress.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3-nitrobenzamide (2-BNBA) is an organic compound that has been shown to have insecticidal properties. It is a quinoline derivative with a cinnabarinus structure and a benzyl group on the nitrogen atom. 2-BNBA was synthesized by modifying the pharmacophore of the natural product cinnabarinus, which is found in the leaves of Cinnamomum zeylanicum. The modification of this pharmacophore led to increased insecticidal activity against tetranychus and other insects. The target compounds for 2-BNBA are sulfide, which are found in cells and tissues of insects such as tetranychus. 2-BNBA inhibits the synthesis of proteins and DNA, leading to death by accumulation of reactive oxygen species within cells.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methylpyrimidine-2-sulfonamide is a pharmaceutical preparation that has been shown to be effective in the treatment of hyperproliferative diseases. It has been found to inhibit cellular proliferation and induce apoptosis in cells from patients with chronic bronchitis, which may be due to its ability to modulate extracellular signal transduction pathways. 4-Methylpyrimidine-2-sulfonamide also has anti-cancer effects, inhibiting the growth of cancer cells by triggering cell cycle arrest or inducing apoptosis. This drug can also lead to symptoms such as nausea, vomiting, and diarrhea, which are indications of a hypersensitivity reaction. The gene sequence analysis was done using DNA from wild type mice and transgenic animals.</p>

<p>Versatile small molecule scaffold</p>

<p>N-(Carbamothioylamino)furan-2-carboxamide is a chemical compound that has been used as a liver protectant and to treat calcium deficiencies. The calcium salt of the drug is prepared by mixing anhydrous ethanol with calcium chloride and adding pyridine dropwise. Upon refluxing, the mixture is cooled and then evaporated under vacuum to yield the desired product.</p>

<p>Versatile small molecule scaffold</p>

<p>2,3,4,5-Tetrahydro-1-benzoxepin-3-one is an acrylamide derivative that has been shown to undergo ring cleavage under certain conditions. The cleavage of the benzene ring leads to the formation of two aromatic rings and a carboxylic acid.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,3,4-Tetrahydropyrido[3,4-b]pyrazine is an organic solvent that has been shown to be a good catalyst for the dimerization of isocyanates. It is used as a basic additive in resins and coatings. 1,2,3,4-Tetrahydropyrido[3,4-b]pyrazine is soluble in most solvents and can be used as a diluent of other solvents. This chemical has been shown to have good thermal stability and low volatility.</p>

<p>6-Chloro-5-formyl-1,3-dimethyluracil is a cyclized compound that is formed from the reaction between a vinyl group and sulfilimine. It has been shown to be a precursor for the synthesis of uracil derivatives by photolysis. 6-Chloro-5-formyl-1,3-dimethyluracil is also an intermediate in the synthesis of analogues of uracil and cytosine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-3-hydroxy-6-iodopyridine is an electrophile that reacts with magnesium to form a reactive intermediate. This intermediate can react with halides to form diaryl compounds and reactive intermediates, which can be used as reagents for organic synthesis. 2-Chloro-3-hydroxy-6-iodopyridine is also a low temperature reactive intermediate and it has been shown to react with sulfonates to form cycloadducts. This compound can be eliminated by reductive amination or hydrolysis, leading to yields of the desired product.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-tert-Butoxybenzonitrile is an organocatalyst that can catalyze the transformation of aryl iodides to aryl radicals, which can then react with organic substrates. It is most often used as a catalyst for the synthesis of α-amino nitriles. 4-tert-Butoxybenzonitrile can be used in the presence of copper salts and N-methylmorpholine to catalyze the reaction of aryl iodides with alcohols. Mechanistic experiments have shown that 4-tert-butoxybenzonitrile operates by radical coupling, generating an alkyl radical intermediate that reacts with the substrate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-N-phenyl-7H-purin-6-amine is a substituted purine that has been shown to have growth promoting properties in cultured callus and excised plants. It also shows cytokinin activity and betacyanin production in wheat leaves, tobacco leaves, and petunia flowers. This compound binds to the betalactamase enzyme, which degrades the antibiotic cephalosporins, causing resistance to this class of antibiotics. The biological activity of 2-Chloro-N-phenyl-7H-purin-6-amine was observed through its ability to activate nitric oxide synthase (iNOS) and inhibit protein synthesis in purified bacterial extracts.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>