Building Blocks

<p>Versatile small molecule scaffold</p>

<p>3-(1H-Imidazol-1-yl)benzoic acid is a heterocyclic organic compound that is used as an excitatory neurotransmitter. It has a high affinity for the metabotropic glutamate receptor and is able to induce excitatory postsynaptic potentials in neurons. 3-(1H-Imidazol-1-yl)benzoic acid binds to the postsynaptic membrane and blocks the ion channels, leading to depolarization of the neuron membrane. The glutamate binding site on the metabotropic glutamate receptor is low nanomolar and five membered, making it a competitive antagonist at this site.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Aminomethyl)-4-chloroaniline is an organic compound that can be synthesized in a sustainable manner. It has been used as an additive for the oxidation of benzyl amines with transition metal catalysts. 2-(Aminomethyl)-4-chloroaniline is also a reagent for the synthesis of quinazoline derivatives and quinazolines. The efficiency of this process has been shown to increase with the substitution of n-substituted benzylamines.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(1S)-1-(2-Methoxyphenyl)ethan-1-ol is a synthetic intermediate that belongs to the class of alcohols. It has been shown to be an enantioselective hydrogenation substrate for the transfer hydrogenation of acetophenones. The compound can also be used in biological synthesis and organic synthesis as a chiral, optically pure building block.</p>

<p>The compound 2-oxo-1H,2H,5H,6H,7H-cyclopenta[b]pyridine-3-carbonitrile is a heterocyclic compound that belongs to the class of tricyclic compounds. It has an anisotropic crystal system and a single crystal x-ray diffraction pattern. The molecular geometry of this compound is a trigonal planar with three atoms in the plane. The molecular weight of 2-oxo-1H,2H,5H,6H,7H-cyclopenta[b]pyridine-3-carbonitrile is 205.08 g/mol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methyl-5-phenylfuran-3-carboxylic acid (2MPFC) is a ligand that binds to the agonist binding site of the 5HT1A receptor. It has been shown to have potent effects on red blood cells, cell function and Alzheimer’s disease. 2MPFC has been shown to activate microglial cells and increase blood pressure in some models. The compound activates the receptor by binding it in an allosteric manner, which is a different mechanism than other ligands that bind at the orthosteric site. This compound also has been shown to be able to reduce dehydration and increase water intake in mice.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-(Benzyloxy)quinoline is a quinoline derivative that is structurally related to trehalose and covalently binds to anilines. It has been shown to selectively inhibit kinases, such as protein kinase A and protein kinase C, with pyridinium and quinolinium as the major metabolites. The compound has been isolated in good yield from betaine and carbodiimides. 6-(Benzyloxy)quinoline has also been found to be amine-labeling reagent for amines, which can be used in bromoacetic acid labeling of proteins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,3-Dihydro-1H-indole-2-carboxamide is a synthetic peptidomimetic that inhibits NS3 protease, which is involved in the viral life cycle. 2,3-Dihydro-1H-indole-2-carboxamide has been shown to have potent inhibitory activity against the hepatitis C virus (HCV) and HIV. It also inhibits the replication of HCV in mammalian cells. This drug has pharmacokinetic properties that are similar to glibenclamide and penetrates the blood brain barrier. Clinical studies have been conducted on patients with chronic hepatitis B and C infection.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dibromo-4-methoxybenzaldehyde is an aromatic compound with a hydroxy group. It has antibacterial activity against the ascidian and Staphylococcus aureus. The nanoribbons of 3,5-Dibromo-4-methoxybenzaldehyde are synthesized from the hydroxyl group of 3,5-Dibromo-4-methoxybenzaldehyde. The kinetic and fluorescent properties of this compound have been studied and found to be similar to those of other quinones.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Naphthalen-1-yl)benzoic acid is an experimental compound that has shown supercooling properties. It is a nonplanar molecule, which may account for its high heat capacity. This compound also has the ability to entrap other molecules in its crystal lattice and can be used for the removal of impurities from organic solvents. 2-(Naphthalen-1-yl)benzoic acid has been used as a kinetic probe to study transport mechanisms, analytical methods, and kinetics of chemical reactions. It has also been studied in relation to the mathematical analysis of molecular motion and molecular interactions in solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Cyano-3-[2,5-dimethyl-1-(4-methylphenyl)-1H-pyrrol-3-yl]prop-2-enoic acid is a research tool for cell biology, pharmacology and ion channels. It is an inhibitor of ligand binding to receptor.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-[(Pyridin-3-ylmethyl)sulfamoyl]benzoic acid is a high purity reagent for life science, pharmacology, receptor, ligand and research tool. This product is widely used in cell biology and peptide studies. 3-[(Pyridin-3-ylmethyl)sulfamoyl]benzoic acid can be used as an inhibitor of ion channels and protein interactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1-Chloroethyl)-5-(thiophen-2-yl)-3H,4H-thieno[2,3-d]pyrimidin-4-one is a small molecule that has been shown to inhibit the activity of calcium channels. It is also known as an inhibitor for research and antibody production. 2-(1-Chloroethyl)-5-(thiophen-2-yl)-3H,4H-thieno[2,3-d]pyrimidin-4-one is a ligand that binds to ion channels and activates them by binding to the receptor on the cell surface. This compound can be used in pharmacology and protein interactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Amino-N-(2-chlorophenyl)-3-(hydroxyimino)propanamide is a potent inhibitor of voltage-gated potassium channels. It was developed as an antibody and has been used as a research tool to study protein interactions, ion channel function, cell biology, pharmacology, and receptor function. 3-Amino-N-(2-chlorophenyl)-3-(hydroxyimino)propanamide binds to the extracellular domain of the potassium channel Kv1.5 and inhibits its activity with an IC50 of 1 nM. The crystal structure of 3-amino-N-(2-chlorophenyl)-3-(hydroxyimino)propanamide bound to the extracellular domain of the potassium channel Kv1.5 has been determined at 2.4 Å resolution by X-ray crystallography.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-(2-Thienyl)-2-pyridinecarboxaldehyde is an experimental compound that has not been tested in humans. It is a liquid at room temperature, with a boiling point of 230°C. 6-(2-Thienyl)-2-pyridinecarboxaldehyde can be injected intravenously, intramuscularly, or subcutaneously. The compound has shown promise in preliminary experiments as a chemotherapeutic agent against cancer and chronic viral infections.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(4-Cyclohexylphenyl)methanol is a potent glutamic acid analog that has been shown to inhibit prostate-specific antigen (PSA) in the human prostate cancer cell line LNCaP. This compound has been synthesized as a lead for optimizing and optimizing PSA inhibitors. It has also been shown to inhibit membrane antigens, which may be due to substitutions at the phenyl ring. The results of this study suggest that (4-cyclohexylphenyl)methanol is a novel inhibitor of PSA, which may have therapeutic potential for the treatment of prostate cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Acetyl-4-bromothiazole (ABT) is a bromoketone that has been used as an efficient and multigram active compound in the synthesis of trimethyltin. ABT is also used as an analogue to synthesize enantiopure thioamides with high yield and biological activity. This compound can be used for the asymmetric synthesis of enantiomers. It was first prepared by reacting 4-bromoacetophenone with sodium methoxide in methanol, followed by acetylation of the resulting 2-acetylthiazole with acetic anhydride.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>