Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(2-Fluoroethyl)piperidine is a synthetic piperidine compound that has been shown to inhibit thrombin. This drug is orally administered and has a long half-life, which makes it suitable for chronic use in humans. 4-(2-Fluoroethyl)piperidine has also been shown to have a modulating effect on platelets and prolong the clotting time. The drug was found to be safe in vivo, with no significant side effects observed. Pharmacokinetic studies showed that the drug is excreted unchanged by both kidneys and intestines, suggesting that its elimination is not mediated by hepatic metabolism.<br>END&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Piperidin-4-yl)acetamide is a cardiac drug that belongs to the class of piperidines. It has been evaluated for its ability to prevent and reverse myocardial infarction in animal models and human clinical trials. The compound has been shown to be safe and well tolerated, with no significant adverse effects or changes in heart rate or blood pressure. 2-(Piperidin-4-yl)acetamide is undergoing further development as a cardiovascular drug, with optimization being carried out on the basis of preclinical pharmacomodulation studies.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-5-hydrazinylbenzoic acid hydrochloride (CHB) is a costimulatory molecule that activates the immune system. It binds to the receptor CTLA-4 and prevents it from binding to its ligand, B7. This prevents the inhibitory signal from being transmitted to T cells and leads to an increase in immune responses. CHB has been shown to be effective in treating bladder cancer as well as other cancer types such as colorectal cancer and esophageal cancer. In addition, this drug has anti-inflammatory effects, which can be attributed to its ability to activate monocytes and macrophages, leading to production of cytokines such as IL-1β and IL-6.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Trifluoromethyl)-1H,2H,5H,6H,7H-cyclopenta[b]pyridin-2-one (CFCl) is a compound that has a number of different applications in the field of optics. It is used as a connector in multiphase systems and can be applied to frequencies ranging from 1 kHz to 300 GHz. CFCl has been shown to be effective at both modulating and deforming optical signals. This chemical compound is also able to act as an antenna for light waves due to its high refractive index. CFCl has been shown to have a constant spectrum with flow rate, which makes it an excellent choice for use in optical devices such as lasers or photodetectors.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Bromo-2,5-dimethoxyphenyl)acetic acid (BODMAP) is a metabolite that is found in urine. It is analyzed to diagnose urinary tract infections and to investigate the role of gut microflora in metabolism. BODMAP can be detected in urine samples after deamination by human enzymes. The benzyl group of BODMAP can be removed by diethylether, forming 2-(4-methoxybenzyl)acetic acid which can then be oxidized to 2-(4-hydroxyphenyl)acetic acid. The presence of aldehyde dehydrogenase in humans allows for the conversion of 2-(4-bromo-2,5-dimethoxyphenyl)acetic acid to 2-(4-hydroxyphenyl)acetic acid. This process may take place in the liver or kidneys as well as other tissues.<br>BODMAP</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Bromo-1-methyl-1H-pyrrol-2-yl)-2,2,2-trichloroethanone (1) is a nitro compound that has the properties of a solvate. It forms monovalent cations when dissolved in water. 1-(4-Bromo-1-methyl-1H-pyrrol-2-yl)-2,2,2-trichloroethanone also has alkyl and aryl groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Fmoc-2-azetidinecarboxylic acid is a synthetic compound that has been shown to enhance receptor binding and act as an enhancer in the presence of protonated aromatic residues. The 1-Fmoc-2-azetidinecarboxylic acid molecule has a proton resonance at around 8.5 ppm, which can be used to identify it. It has also been shown to bind to the receptors with high affinity. This compound has a conformational effect on the receptor that enhances its binding activity. 1-Fmoc-2-azetidinecarboxylic acid is made up of an aromatic ring with two methyl groups and one hydrogen atom on either side of the ring. This gives it a spectrum with three peaks at 8.25, 8.5, and 9.0 ppm in the nmr region, which can be used to identify it if needed.br&gt;br&gt;1-Fmoc-2-</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-1-cyclopropyl-1H-1,3-benzodiazole is a drug that acts as an antagonist of the 5HT receptor. It has been shown to have anticancer activity against certain cancer cells. This drug is also used as a pharmacological agent for the treatment of nausea and vomiting. 2C10CB has low affinity for the 5HT receptor, with an IC50 in the range of 1 μM to 10 μM. Binding assays indicate that this drug has a higher binding affinity for serotonin receptors than other receptors. The binding affinities of 2C10CB are similar to those of granisetron, which is used as a pharmaceutical agent to treat nausea and vomiting.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>