Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Rupatadine is a drug that has been shown to have antihistamine and anticholinergic properties. It is used for the treatment of allergic rhinitis, chronic idiopathic urticaria, and pruritus. Rupatadine has also been investigated for its potential use in the treatment of solid tumours. Rupatadine belongs to a class of drugs called histamine H1 receptor antagonists. In experimental models, it has been shown to inhibit the growth of certain types of cancer cells by blocking the activity of histamine receptors on cell membranes and inhibiting protein synthesis. The drug also inhibits cardiac potassium channels, which may lead to cardiac effects such as arrhythmias or heart block. Rupatadine fumarate is metabolized into rupatadine (RUP) by esterases and oxidized by cytochrome P450 enzymes or conjugated with glucuronic acid. This active form binds to proteins</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethynylcycloheptane is a cyclic ether that contains a ring of seven carbon atoms. It has two isomers: the homologous isomer and the positional isomer. The homologous isomer has the same number of hydrogen atoms on each carbon atom, while the positional isomer has different numbers of hydrogen atoms on some of its carbons. The odorant property of this chemical makes it useful as an additive in perfumes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 5-(chlorosulfonyl)pentanoate is a colorless liquid that is soluble in hexane, insoluble in water, and has a boiling point of 190-195°C. It can be used as an eluant for purification of amines. The reagent can be prepared by refluxing the chloride with the methyl 5-chloropentanoate in organic solvents such as chloroform or dichloromethane. The filtrate is then evaporated to dryness under vacuum to yield the product.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-(2-Thienyl)-2-pyridinecarboxaldehyde is an experimental compound that has not been tested in humans. It is a liquid at room temperature, with a boiling point of 230°C. 6-(2-Thienyl)-2-pyridinecarboxaldehyde can be injected intravenously, intramuscularly, or subcutaneously. The compound has shown promise in preliminary experiments as a chemotherapeutic agent against cancer and chronic viral infections.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(4-Cyclohexylphenyl)methanol is a potent glutamic acid analog that has been shown to inhibit prostate-specific antigen (PSA) in the human prostate cancer cell line LNCaP. This compound has been synthesized as a lead for optimizing and optimizing PSA inhibitors. It has also been shown to inhibit membrane antigens, which may be due to substitutions at the phenyl ring. The results of this study suggest that (4-cyclohexylphenyl)methanol is a novel inhibitor of PSA, which may have therapeutic potential for the treatment of prostate cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Acetyl-4-bromothiazole (ABT) is a bromoketone that has been used as an efficient and multigram active compound in the synthesis of trimethyltin. ABT is also used as an analogue to synthesize enantiopure thioamides with high yield and biological activity. This compound can be used for the asymmetric synthesis of enantiomers. It was first prepared by reacting 4-bromoacetophenone with sodium methoxide in methanol, followed by acetylation of the resulting 2-acetylthiazole with acetic anhydride.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-1-methylpyrrolidin-2-one is a homologous compound that can be synthesized from physostigmine and lactams. It is a nucleophilic reagent that can act as an efficient chemoselective agent for the synthesis of six-membered ring alkaloids. 3CMP has been used in many organic chemistry reactions and has shown high yield in most cases. This compound is also used to prepare tricyclic compounds, including the antihypertensive drug amlodipine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenylmethylidenecyclobutan-1-one is a cyclic ketone that can be synthesised by thermal rearrangement of the enolate anion of 2,2-dimethylcyclopropane carboxylic acid. The thermally induced isomerisation is reversible and the equilibrium lies in favour of the starting material. This compound has an optical isomerism, with one form (enantiomer) being chiral and the other not. The suprafacial enolate anion reacts with electrophiles at the carbonyl carbon to form a 1,2-didehydrobenzene or a 1,4-didehydrobenzene. <br>The compound also undergoes a series of stereochemical changes when it reacts with nucleophiles such as methanol or water, forming dimers in which two molecules are linked by an oxygen bridge.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Benzoxazole-4-carboxylic acid is a metabolite of benzoxazinone and has been shown to have antibiotic properties. It was found to inhibit the growth of bacteria by binding to their ribosomes and inhibiting protein synthesis. This compound also inhibits acetylcholinesterase activity in tissues and skeletal muscle, which may be due to its ability to bind with phosphatidic acid and phospholipases. 1,3-Benzoxazole-4-carboxylic acid has been shown to accumulate in the esophagus in rats after oral administration. In one study, this compound was found to reduce the number of colonies grown on plates containing strains of E. coli and S. aureus.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Formyl-1H-indole-4-carboxylic acid is an intermediate in the synthesis of 4-cyanoindole. It is produced by the Vilsmeier-Haack reaction of formaldehyde, ammonia, and phthalic anhydride.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methyl-1,2-dihydrospiro[indole-3,4'-piperidine] is a versatile compound that finds applications in various fields. It is commonly used as an amine in the production of herbicides and is also available in buffered form as maleate or acetal. This compound has been found to exhibit inhibitory effects against Penicillium digitatum, a common plant pathogen. Additionally, it is utilized as a research chemical in organic synthesis experiments.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>