Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-(Chloromethyl)phenanthridine is a fatty acid that has been shown to have anti-inflammatory effects. It has also been shown to be effective in the treatment of humans and animals with musculoskeletal disorders. 6-(Chloromethyl)phenanthridine is soluble in deionized water and hydroxide solution, but insoluble in ethanol and acetone. This compound can be used as an ingredient in detergent compositions for use on clothes. It can also be used as a microcapsule coating material or as an acid catalyst in the production of soybean extract.</p>

<p>Versatile small molecule scaffold</p>

<p>2,3-Dihydro-5-hydroxybenzo[b]furan (2,3-DHBF) is a molecule that has been shown to have synergistic interaction with human polymorphonuclear leukocytes. This compound has also been found to inhibit the peroxidase-like activity and lipolytic enzymes of these cells. 2,3-DHBF may act as an antiinflammatory agent by inhibiting the production of inflammatory mediators. It also has antioxidant properties due to its ability to scavenge free radicals and protect against lipid peroxidation. The compound is soluble in organic solvents and can be synthesized from sulfonic acids and selenium compounds. 2,3-DHBF has also been found to have cytotoxic effects on heart tissue in rats.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a liquid crystal with a molecular weight of 244.3 g/mol. It is synthesized from benzaldehyde and 4-bromobenzaldehyde in the presence of sodium hydroxide and potassium carbonate in methanol at reflux temperature. The compound crystallizes as an asymmetric carbon atom with a biphenyl skeleton. It has been shown to be soluble in chloroform and benzene, but not in ether or acetone. The compound exhibits ferroelectric properties and has been used for the synthesis of dendrimers and supramolecular structures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Aminothieno[2,3-d]thiazole is a heterocyclic compound that has been used as a building block in organic synthesis. It has been found to be an intermediate in the deamination of 2-aminopyrimidine and the reductive chlorination of ethyl or benzyl thiocyanate. 2-Aminothieno[2,3-d]thiazole is produced by the decarboxylation of 2-aminoacetophenone and can be oxidized to produce 2,4-diaminothiazole. The optical rotation varies with the solvent used, with values given for ethanol being [α] = -8.5° (c=0.1 in HCl) and for methanol [α] = +6.7° (c=0.1 in HCl).<br>2-Aminothieno[2,3-d]thiaz</p>

<p>Versatile small molecule scaffold</p>

<p>Chloromethyl cyclohexyl carbonate is a new acyclic nucleoside phosphonate that has been shown to have antiviral properties. It is active against HIV strains and inhibits the production of clotting factors. Chloromethyl cyclohexyl carbonate can be used as a drug substance for treating bowel disease, hepatitis, and cancer. It also modulates syncytial cells and heterocycles. Pharmacokinetic studies on chloromethyl cyclohexyl carbonate have shown that it has high bioavailability in the small intestine and liver after oral administration. It is metabolized by tyrosine kinase, which indicates that it may interfere with other drugs such as warfarin or phenytoin. Chloromethyl cyclohexyl carbonate has been found to be effective in treating gastritis and cancer in animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Boc-amino)-2-(3-thiophenyl)acetic acid is a synthetic polymer that is synthesized from ethynyl bromide and 3-thiophenylacetic acid. It is conjugated to a model compound, which has been shown to fluoresce. This polymer can be used as a model for polymers with similar properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pseudomonas aeruginosa is a Gram-negative bacterium that has been implicated in many infectious diseases. It is a multidrug resistant organism and can be difficult to treat. The mode of action of 2-heptylquinolin-4(1H)-one (2HQ) is not well understood, but it appears to inhibit the growth of P. aeruginosa by binding to copper ions. 2HQ was shown to exhibit antibacterial activity against wild-type strains of P. aeruginosa as well as mutants with reduced copper resistance. 2HQ also reduces the virulence and biofilm formation of P. aeruginosa cells and inhibits the expression of genes involved in energy metabolism, signal transduction, and chlorogenic acid biosynthesis (an endpoint for quorum sensing).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl propionimidate hydrochloride is a non-selective, irreversible inhibitor of the glutamate-gated chloride channel. It is used to treat some types of psychosis, esophageal spasms, and prostatic hypertrophy. It has also been shown to inhibit metabotropic glutamate receptors and inflammatory diseases. This drug binds to an oxygen atom in the active site of the glutamate receptor and blocks its activity. Ethyl propionimidate hydrochloride has been shown to be effective against animal health as well as obesity in animal models. This drug does not have any effect on insulin resistance or blood glucose levels but does have a relaxing effect on bronchial muscles.</p>

<p>3-Bromopyrrolidin-2-one is a homolytic, dehydrohalogenation thermochemical reagent that induces chemical diversity. It is synthesised from brominated and chloride compounds and has been used for the synthesis of 8-bromoadenine. The energy of the molecule is 8.1 kcal/mol, which makes it relevant in the dehydrogenation of organic compounds. 3-Bromopyrrolidin-2-one can be used as a reagent to induce chemical diversity.</p>

<p>2-tert-Butylcyclopentan-1-one is a small molecule that can be used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is an example of a stereocontrolled reaction, which means that the product has been synthesized by using a specific stereocenter to direct the product's configuration. This molecule has been synthesized from two different fluorine sources in order to create a pseudoequatorial structure. The selectivity for this reaction was determined by observing x-ray crystallography data and nmr spectra. The temperature at which this reaction occurred was determined through correlations between chiralities of cyclic hydroxyalkyl groups with temperatures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2-Bromophenoxy)pyridazine is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR), which is found on the surface of cancer cells. It can also be used to diagnose cervical cancer in women. The 3-(2-bromophenoxy)pyridazine was developed to find a treatment for cancers that have EGFR receptors, and it has been shown to be potent in inhibiting tumor growth in vivo. This drug binds to the EGFR with an affinity that is comparable to those of natural antibodies, and it has been shown to have no adverse effects on normal cells.<br>The 3-(2-bromophenoxy)pyridazine does not bind as well to some cell types, such as those from mice or rats. This may be due to the effect of the matrix on the binding process.</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,3,4,5,6-Hexahydro-3-benzazocine is a cyclopropylcarbonyl compound with analgesic properties. It is used in the treatment of moderate to moderately severe pain. This drug has been shown to bind to benzene ring and form an aliphatic bond with a hydroxy group on the adjacent carbon. The binding of the hydroxy group is stabilized by the methoxy and cycloaliphatic groups. 1,2,3,4,5,6-Hexahydro-3-benzazocine also binds to aluminum cations through its hydride or aralkyl groups and forms a stable complex that can be removed from solution by dialysis. The phenylacetyl group is used for solubilization.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2-Oxo-2-(thiophen-2-yl)ethyl)quinoxalin-2(1H)-one is a medicament with aromatase inhibition properties. It acts by inhibiting the enzyme aromatase, which is responsible for the conversion of androgens to estrogens. This compound has been found to have potential therapeutic applications in the treatment of hormone-related conditions such as breast cancer and endometriosis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Pyridin-2-yl)butane-1,3-dione is a hydrazine derivative that is used as a research tool for the synthesis of heterocycles. It has been found to react with sodium borohydride in the presence of formic acid to yield various pyrazoles and formic acid. 1-(Pyridin-2-yl)butane-1,3-dione can also be used to reduce aldehydes, ketones, and other compounds containing an alpha carbon.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-1-benzofuran-2-carbaldehyde is a chemical that belongs to the group of heterocyclic compounds. It has the ability to act as an acceptor and chloride. 3-Chloro-1-benzofuran-2-carbaldehyde has been shown to be toxic to kidney cells, which may be due to its ability to cause chloride ion accumulation in the cell. 3-Chloro-1-benzofuran-2-carbaldehyde also acts as a virus inhibitor, and it has been shown that it inhibits the replication of viruses by reacting with their DNA. This chemical can also react with alkylating agents and form acetylated or formylated derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Dichloro(isocyanato)methane is a chemical compound that belongs to the haloalkyl group. It can be used in dyestuffs, as a reagent for the modification of quinoline derivatives, and in the production of nitro compounds. Dichloro(isocyanato)methane has two isomers: monochloro-dichloromethane and dichloro-monochloromethane. The former is a kinetic product while the latter is thermodynamic. This compound is also polymorphic and has two expressible forms: one with an electron density on chlorine atom and another with an electron density on carbon atom.</p>

<p>Cyclooctanecarbonitrile is a hydroxy group that is used as a polymerization initiator. It can be synthesized by the reaction of cyclooctane and carbon monoxide. Cyclooctanecarbonitrile is an amine with a homogeneous catalyst, which also has functional groups such as an isopropyl group. Cyclooctanecarbonitrile is used in industrial processes to make polyvinyl chloride (PVC) and ethylene vinyl acetate (EVA). This compound also has the ability to inhibit insulin resistance and may be useful for treating diabetes. The polymerization of cyclooctanecarbonitrile can be catalyzed by titanium or zirconium.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>