Building Blocks

<p>Versatile small molecule scaffold</p>

<p>(2-Hydroxyphenyl)acetonitrile is a benzofuran derivative that has been shown to be an effective inhibitor of amide synthetase. It is soluble in polar solvents and immiscible in apolar solvents, which makes it a useful reagent for the synthesis of amides from primary amines. The compound was isolated from a strain of Streptomyces sp. with the gene sequence identified and sequenced. The compound exhibits high specificity against the enzyme and can be used as a tool in biomolecular studies.</p>

Nitrite ion is a gas that is found in the environment and has been shown to have various beneficial effects. Nitrite ion has been shown to have hepatoprotective properties, as it protects rat liver cells from death by benzalkonium chloride. This substance also prevents neuronal death in an experimental model of cerebral ischemia.

<p>Versatile small molecule scaffold</p>

<p>5-(Hydroxymethyl)-3-methylisoxazole is a chloride heterocycle that has been shown to be an agonist of the adenosine A3 receptor. It has been synthesised by reacting 2-chlorobenzaldehyde with methyl hydroxymethyl ketone and nitroethane. 5-(Hydroxymethyl)-3-methylisoxazole has been used in screening tests for the identification of novel biomolecules with desirable functionalisation. The yields of synthesized isoxazoles have been found to be improved by irradiation. This heterocycle has also been used in the synthesis of isoxazolines, which are a class of compounds that are structurally related to benzoxazinones and benzothiazinones.</p>

<p>Versatile small molecule scaffold</p>

<p>2,2,4-Trimethylheptane is a volatile organic compound with a strong odor. It is used as a modeling or calibration standard for the analysis of other volatile compounds. The headspace technique can be used to extract 2,2,4-trimethylheptane from samples. Solid phase extraction can also be used to remove 2,2,4-trimethylheptane from samples. This compound has been found in the environment due to its presence in gasoline and cigarette smoke.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Chloromethyl)-5-phenylisoxazole is a water soluble moiety that is used in the synthesis of conjugates with antitumor activity. 3-(Chloromethyl)-5-phenylisoxazole has been shown to inhibit the growth of brain tumors by binding to DNA, inhibiting transcription and replication. The drug also inhibits protein synthesis and cell division. This compound can be esterified and isothiazole substituted to form an antitumor drug that has a strong antiproliferative effect on human leukemia cells. The biological activity of 3-(chloromethyl)-5-phenylisoxazole can be enhanced by catalytic hydrogenation with methanol in acidic conditions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methoxy-2-oxoethyl)benzoic acid is an organic compound that can be synthesized by the reaction of 2-methoxyacetophenone with lithium borohydride. It is also obtained as a byproduct in the synthesis of other organic compounds, such as esters and anhydrides. The chloride group of 2-(2-methoxy-2-oxoethyl)benzoic acid can be replaced with other groups to produce homophthalic, acetyl, or anhydride derivatives. 2-(2-Methoxy-2-oxoethyl)benzoic acid is often used as a starting material for the synthesis of cyclic esters and alcohols. It has been used in the synthesis of drugs such as dipyridamole and dapsone.</p>

<p>2-Amino-5-phenyl-3-furonitrile is a heterocyclic compound that belongs to the group of pyrimidine derivatives. It can be prepared by the reaction of 2,4,6-trichloropyrimidine with phenylacetonitrile and sodium hydroxide in water. This synthesis gives high yields of 2-amino-5-phenyl-3-furonitrile. The compound reacts with isothiocyanates to form heterocyclic compounds. The process of catalyzed heterocyclization has been shown to be effective for the synthesis of pyrimidine derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Formylfuran-3-carboxylic acid is a furan derivative with an oxidation product that has been shown to be useful as a peroxide scavenger. It is synthesized by the reaction of 2-formylphenol and formaldehyde in the presence of copper salts. The molecular modelling studies revealed that this compound consists of a five membered ring with an oxygen atom at its centre, which is flanked by two carbon atoms at each side. The carboxylic acid group (-COOH) is on one end and the hydroxymethyl group (-CHOH) on the other end. The molecule also has a carbonyl group (-C=O) and a methylene bridge (-CH2-) between the two carbon atoms. This compound has been found to have efficient antioxidant properties when it reacts with reactive oxygen species (ROS). It was also found to have antioxidative activities when it reacts with ROS produced by galacturonic acid and fur</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methanesulfonylphenol is a reactive and computationally descriptors, damages, neutralizing, piperidine, vector, oxygen species, molecular descriptors, antioxidant, phenolic lead compound that was synthesized for the purpose of identifying new potential antioxidants. 3-Methanesulfonylphenol has been shown to inhibit the oxidation of lipids and proteins in cells. It also has a strong antioxidant activity against peroxyl radicals and hydroxyl radicals. 3-Methanesulfonylphenol also inhibits the production of hydrogen peroxide by reacting with peroxides in vivo. This results in reduced levels of lipid hydroperoxides and protein carbonyls.</p>

<p>2-Benzoyl-4-methoxyphenol is a surfactant that is sustainable and biodegradable. It is used in the production of micelles to form detergents, which are important for the environment. The binding constants of this chemical with 2-hydroxybenzophenone and benzyl have been determined at different temperatures. 2-Benzoyl-4-methoxyphenol has been shown to be an effective transient probe for mechanistic investigations in organic chemistry. This compound can be prepared by reacting benzaldehyde with methoxyacetophenone in acetonitrile. Irradiation can break down the benzene ring, producing phenoxy (2,6-dioxo)cyclohexane or 2-(2,6-dioxo)cyclohexanone. 2-Benzoyl-4-methoxyphenol also has hydrophobic properties and can be used as a surf</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-Hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione is a natural product that has been found to have anticancer activity. It induces apoptosis in human cancer cells and inhibits the growth of bacteria by binding to the 50S ribosomal subunit. 8HMN has also been shown to inhibit the proliferation of cervical cancer cells in vitro. The active form of this compound is acetate extract and it has been shown to have strong anti-inflammatory properties by inhibiting prostaglandin synthesis in neutrophils. 8HMN binds to mitochondrial membrane protein complexes, leading to mitochondrial fission and inhibition of ATP production.</p>

<p>3-Methyl-2,3-dihydro-1,3-benzothiazol-2-imine is an imine nitrogen that is a ligand for transition metals. It is used in the synthesis of 1,3-benzothiazoles and has been shown to have anti-malarial activity. 3-Methyl-2,3-dihydro-1,3-benzothiazol-2-imine interacts with aldehydes to form ring opening products. This compound also has been shown to be a ligand for palladium and platinum metals. The compound has been functionalized with thiol groups and can be used as a reagent in organic synthesis.</p>

<p>7-Methylbenzo[d]thiazol-2-amine is an antimicrobial agent that has been shown to have both antibacterial and antifungal properties. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, as well as fungi. 7-Methylbenzo[d]thiazol-2-amine also inhibits the growth of yeast cells by interfering with their ability to produce proteins necessary for cell division. This drug can be synthesized using a number of different techniques, including the reaction between phenyl mercaptan and dimethyl acetylenedicarboxylate in the presence of aluminium chloride or phosphorus pentachloride. The yield is typically low (5%).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-1-(4-ethoxyphenyl)ethan-1-one is a hydrocarbon radical that is used as a vitamin and in the synthesis of other molecules. This molecule has a covalent bond between the two chlorine atoms and one carbon atom. The hydrocarbon radical is also present in many hydrocarbons.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromoquinolin-4-ol is a pyrrole derivative with a hydroxy group on the 4 position. It is an intermediate in the synthesis of 3-bromo-5-hydroxypyridine, which can be used as a reagent for aminations, oxindole syntheses, and piperidide formation. The presence of substituents on the 2 position of the quinoline ring determines whether it is an isomeric or nonisomeric compound. Substituents on the 2 position also determine if it is a nucleus or not. Finally, a substitution at the 4 position determines whether it is 2-amino-4-hydroxypyridine or pyrrole derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-methyl-5-nitroquinoline is a linker that has been shown to be cytotoxic in tumor cells. It binds to DNA by forming covalent bonds and inhibits the synthesis of DNA. 8-methyl-5-nitroquinoline is also able to inhibit the growth of human colon carcinoma cells in vitro and tumor xenografts in vivo. This nitro compound has been shown to cause necrosis, which may be due to its ability to bind oxygen and generate reactive oxygen species. The ability of 8-methyl-5-nitroquinoline to form covalent bonds with DNA makes it a potent antioxidant that may be used for the treatment of radiation injury.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Naphthalene-1-carbonyl naphthalene-1-carboxylate is a benzoylation of a primary alcohol. It is a monosubstituted benzoyl derivative with a transition state that has a benzoic anhydride and enolate as reactants. It is not an alkylation reaction because the carbonyl group prevents the formation of an alkyl bond. The kinetic product, which is favored in this reaction, is the cyclic sulfate ester. The carboxylate group can be either chiral or non-chiral depending on the configuration of the starting material. The R/S system for naphthalene-1-carbonyl naphthalene-1-carboxylate would be S/R because it has no chiral atoms. Naphthalene-1-carbonyl naphthalene-1-carboxylate can also form chiral alcohol</p>

<p>Versatile small molecule scaffold</p>

<p>5-(Chloromethyl)-3-cyclohexylisoxazole is an aliphatic aldehyde. It reacts with aldoximes to form cyclic imines, and then undergoes nucleophilic substitution with sodium hydroxide to produce the corresponding oxime. This reagent can be used for the synthesis of 2-amino-1,3-dioxolane compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Spiro[2.5]octane-7-carboxylic acid is an industrial chemical that is used in the synthesis of other chemicals, such as pharmaceuticals and dyes. It can also be used for the production of solvents, such as ethanol and methanol. The compound is synthesized from a reaction between p-toluenesulfonic acid and magnesium chloride to produce magnesium sulfate, which reacts with ethyl bromide to form spiro[2.5]octane-7-carboxylic acid. Spiro[2.5]octane-7-carboxylic acid can also be synthesized by reacting potassium tert butoxide with isobutyryl chloride in ether at room temperature. This reaction produces a Grignard reagent that reacts with p-toluenesulfonic acid in ether to form spiro[2.5]octane-7-carboxylic acid.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>