Building Blocks

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-2-methylphenyl)hydrazine is a nitrogenous organic chemical that has the molecular formula CHClN. It is a basic compound with a pKb of 16.1 and an elemental analysis of C, 72.63%; H, 6.25%; N, 17.76%. 4-Chloro-2-methylphenyl)hydrazine is soluble in chloroform and insoluble in water. This chemical forms adducts and chelate complexes with metal ions such as nickel and cobalt, but does not form complexes with copper or zinc ions.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

2,6-Dimethoxypyridine-3-carbaldehyde is a chemical that is used in the production of other chemicals. It is also used as an antifungal agent in vitro. 2,6-Dimethoxypyridine-3-carbaldehyde is activated by irradiation with ultraviolet light. The yield and reactivity are increased when it is used in the presence of catalysts such as thiosemicarbazide. Candida albicans and Aspergillus parasiticus can be inhibited by this compound at low concentrations. 2,6-Dimethoxypyridine-3-carbaldehyde has been shown to inhibit growth of Aspergillus on a petri dish, but not Candida albicans cells. This may be due to its inability to cross the cell membrane or because Candida albicans cells are able to synthesize their own pyridoxine (vitamin B6).

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromofuran-4-carboxylic acid is a heterocyclic compound that has been reported in the synthesis of dioxaspiro[5.5]undecane frameworks. It is also found in the synthesis of butenolides and intramolecular reactions. The synthetic studies on 2-bromofuran-4-carboxylic acid have shown that it can be used as a building block for heterocycles with novel structures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-2-methylbenzofuran is a chiral compound that has been shown to stabilize the DNA of irradiated, homochiral DNA. It is also used as an intermediate in the synthesis of other compounds. 3-Bromo-2-methylbenzofuran has a high melting point, which makes it difficult to purify. The compound crystallizes unsymmetrically and fluoresces. It can undergo photochromism and isomerization under ultraviolet light. 3-Bromo-2-methylbenzofuran has a low solubility in water and can be toxic if inhaled or ingested. This compound exhibits fluorescence properties, which may be due to its ability to absorb light at wavelengths longer than 400 nm and emit light at wavelengths shorter than 400 nm.</p>

<p>5,8-dimethoxyquinoline is a nitrate that is used in the synthesis of heterocyclic compounds. It can be prepared by alkylation of 5,8-dimethoxybenzaldehyde with methyl iodide and sodium nitrite in the presence of ethanol or by the reaction of 2-nitropropane with benzaldehyde. The n-oxide of this compound has been shown to have activity against solid tumours and human lung carcinoma cell lines. 5,8-Dimethoxyquinoline reacts with dimethylhydrazone to form an unstable carbonyl intermediate which undergoes a 1,2-shift in nmr chemical shift.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ellagic acid is a potent inhibitor of the uptake of carbon nanotubes in animals. It also has antiviral properties, which may be due to its reactive oxygen species-generating properties. Ellagic acid has been shown to inhibit the proliferation of human T cells in vitro and induce apoptosis. This compound also inhibits the growth of cervical cancer cells and blocks viral replication by inhibiting viral protein synthesis. Ellagic acid can be used as a structural biology probe to investigate the reaction between cellulose derivatives and molecules. It is also used in pharmaceutical preparations such as anti-cancer drugs and treatments for herpes simplex type I virus infections.</p>

<p>(2-(Trifluoromethyl)thiazol-4-yl)methanol is a benzimidazole derivative that inhibits the activity of imidazopyridine N-acetyltransferase, which is an enzyme involved in the synthesis of histamine. It has shown to be selective for this enzyme and not affect other enzymes related to histamine synthesis. (2-(Trifluoromethyl)thiazol-4-yl)methanol does not show mutagenicity or genotoxicity in f344 rats and has a low safety profile when tested on humans. This drug has been shown to have antiobesity effects, which are likely due to its inhibition of histamine synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Ritonavir is a protease inhibitor that belongs to the class of HIV-1 protease inhibitors. It inhibits the activity of the virus by binding to the active site of the enzyme and blocking it from cleaving proteins. Ritonavir is used with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART). This drug is also used in combination with other protease inhibitors, such as indinavir and saquinavir, to treat HIV infections that are resistant to these drugs. In some cases, ritonavir can be administered without a booster agent such as cobicistat or lopinavir/ritonavir. This drug has been shown to have pharmacokinetic parameters that are similar in healthy volunteers and patients infected with HIV-1.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,2-Difluoropropane-1,3-diamine-2hcl is a potent inhibitor of efflux pumps. This compound binds to the protein in the pump and prevents it from functioning properly. 2,2-Difluoropropane-1,3-diamine-2hcl is active against inhibitors that bind to the cytoplasmic side of the membrane and are transported out of the cell by means of an efflux pump. It has been shown to inhibit interactions with both hydrogen bond and covalent binding sites on proteins. 2,2-Difluoropropane-1,3-diamine-2hcl also inhibits permeability of cells to drugs that are normally transported by these pumps.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>1-(Dimethylsulfamoyl)pyrazole is a synthetic compound that is used as a catalyst in the coupling of aryl groups. It is an effective catalyst for the synthesis of pyrazoles and other substituted pyrazoles. This compound also has been found to be an effective catalyst for the bromo-arylation of benzene and other aromatic substrates, which allows for the introduction of substituents at various positions on the aromatic ring. 1-(Dimethylsulfamoyl)pyrazole has shown to be effective in bond cleavage reactions, specifically those with aliphatic C-H bonds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The emission of this dye is quenched by the presence of an electron donor, such as a solvent or a biomolecule. When the electron donor is removed, it can emit light. This property makes it a good fluorescent probe for biological systems. The fluorescence of this dye is enhanced by introducing a red-shifted excitation wavelength and increased quantum yield. It has been shown to be selective for proteins in the presence of other biomolecules, such as nucleic acids and lipids.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]aniline is a research tool that inhibits antibody production by binding to the enzyme immunoglobulin E (IgE) and preventing its activation. It also has been shown to inhibit the production of peptides, which are important in cell biology, pharmacology, and ligand binding. 2-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]aniline has shown to be an activator for ion channels as well as a receptor for proteins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-4-iodophenol is a synthetic compound that is used in the synthesis of medicines. It is also used to study biological properties and population dynamics. 2-Bromo-4-iodophenol has been shown to interact with adenine nucleotide, which provides it with a radioisotopic skeleton that can be detected by chromatography. This substance has also been found to be able to catalyze the decomposition of bromophenols, which are functional groups in some medicines. 2-Bromo-4-iodophenol can be used as an intermediate for donepezil, a medicine for Alzheimer's disease and other neurodegenerative diseases.</p>

<p>Methyl 2-(bromomethyl)-4-nitrobenzoate is a nitro compound that is used as the starting material for the synthesis of polyglutamate. It has been shown to be an analog of glutamine, which may have chemotherapeutic effects by blocking tumor cells from proliferating. Methyl 2-(bromomethyl)-4-nitrobenzoate is catalytically reduced to yield methylene dinitrobenzene, which reacts with ammonia and formaldehyde in the presence of a reductive coupling catalyst to give polyglutamate. The amide group can be converted into an ester or an amine by acidolysis or reductive amination.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(1H-1,2,4-Triazol-1-yl)butyric acid is a benzimidazole derivative that has shown interaction with imidazole. It is used as an intermediate in the synthesis of other compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>