Building Blocks

<p>Applications (2Z)-2-Penten-1-ol is one of the aroma volatiles in basil and thyme leaves with antioxidant activity.<br>References Lee, S., et al.: Food Chem., 91 131 (2004);<br></p>

<p>Applications 2-Methylphenylboronic acid (cas# 16419-60-6) is a useful research chemical.<br></p>

<p>Applications rac-Trifluorolactic Acid is a derivative of DL-Lactic Acid (L113490) which occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity.<br>References He, W. et al.: Comp. Biochem. Phys. Part A: Mol. Int. Phys., 166, 308 (2013)<br></p>

<p>Applications (±)-3-Heptanol, is a volatile components of various plants, and can be used as flavor and fragrance ingredients. It is also used as building block used for the synthesis of various chemicals. It is used for the preparation of biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, I., et al.: Bioorg. Med. Chem. Lett., 55 (18), 5889 (2012); Gibka, J., et al.: Zeszyty Naukowe - Politechnika Lodzka, 60, 65 (1998);<br></p>

<p>Applications 2-Hydroxy-1-phenylpentane is an impurity of Prolintane (P756100) synthesis.<br>References Hucker, H.B. et al.: Experientia, 28, 430 (1972); Hollister, L.E. et al.: J. Clin. Pharmacol. J. New Drugs, 10, 103 (1970); Kuitunen, T. et al.: Meth. Find. Exp. Clin. Pharmacol., 6, 265 (1984):<br></p>

<p>Applications 4-Hydroxyphenylacetonitrile (cas# 14191-95-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,4-Cyclohexanedione, is a versatile building block in the synthesis of more complex compounds. This intermediate can be hydrolysed and decarboxylated to afford the desired dione.<br>References Nielsen. A.T., et al.: Org. Synth.,;Coll., 5, 288 (1973);<br></p>

<p>Applications 1-Acetylnaphthalene is used in the preparation of S(-)-1-(1'-naphthyl) ethanol, an important synthetic intermediate of mevinic acid analog.<br>References Kamble, A.L. et al.: J. Mol. Catal. B Enzym., 35, 1 (2005); Bhattacharyya, M. et al.: Biores. Technol., 98, 1958 (2007);<br></p>

<p>Applications 2-BROMO-1-PHENYLPROPANE (cas# 2114-39-8) is a useful research chemical.<br></p>

<p>Applications 2,2,6,6-Tetramethyl-4-piperidinone (cas# 826-36-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-chloro-1-(4-chlorophenyl)ethanone (cas# 937-20-2) is a useful research chemical.<br></p>

<p>Applications 3-(Aminomethyl)pyridine is a compound useful in organic synthesis. A pyridine derivative with vasodilating activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Uno, B. E., et al.: Adv. Syn. Catal., 360, 1719 (2018); Trcka, V., et al.: Pharmazie, 11, 242 (1956)<br></p>

<p>Applications Ethyl 2-Oxo-2-(2-oxotetrahydrofuran-3-yl)acetate is an intermediate formed in the synthesis of 5-[[(Dimethylamino)iminomethyl]amino]-2-oxopentanoic Acid (D471015), a metabolite of asymmetric dimethylarginine.<br>References Martens-Lobenhoffer, J. et al.: Anal Biochem., 419, 234 (2011)<br></p>

<p>Applications 3-BENZYLADENINE (cas# 7280-81-1) is a useful research chemical.<br></p>

<p>Applications Propyl Acetoacetate is used as a reagent in the synthesis of 3,4-dihydropyrimidin-2(1H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists.<br>References Crespo, A., et al.: ACS Med. Chem. Lett., 4, 1031 (2013)<br></p>

<p>Stability Volatile<br>Applications Hexamethyldisilane is an organic silylating and disilylating reagent. It is also a useful reagent for reductive coupling, reductive deuteration, aroylarylation, carbosilylation, insertion, deuteration and dimerization reactions.<br>References Xiao, G., et al.: Tetrahedron Lett., 59, 1836 (2018); Lu, A., et al.: Angew. Chem. Int. Ed., 57, 3233 (2018); Deb, M., et al.: New J. Chem., 41, 14528 (2017); Hiyama, T., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2010)<br></p>

<p>Stability Moisture Sensitive<br>Applications Cyclopropanecarbonyl Chloride is a reagent used in the synthesis of orally bioavailable HCV NS5A inhibitor for the treatment of Hepatitis C virus.<br>References Kang, IJ. Med. Chem., 60, 228 (2017);<br></p>

<p>Applications Pyridine hydrobromide (cas# 18820-82-1) is a useful research chemical.<br></p>

<p>Applications 3-Methoxypropionitrile (cas# 110-67-8) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Aminomalononitrile p-toluenesulfonate is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors.<br>References Jeong, S., et al.: J. Org. Chem 63, 8640 (1998); Morwick, T. et al.: J. Med. Chem. 49, 2898<br></p>

<p>Applications 1,4-Cyclohexanediol is used as a reagent in the development of noviomimetics as C-terminal Hsp90 inhibitors.<br>References Anyika, M., et al.: ACS Med. Chem. Lett., 7, 67 (2016)<br></p>

<p>Applications 1-Bromodecane is used to react with Mg to prepare Grignard reagents which play an important role in formation of carbon-carbon bond. It is also used in preparation of biodegradable cationic gemini surfactants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rogers, R., et al.: J. Org. Chem., 39, 857 (1975); Talaba, P., et al.: J. Carbohyd. Chem., 16, 573 (1997); Jain, T., et al., J. Mater. Chem. C: Materials for Optical and Electronic Devices, 2, 994 (2014)<br></p>

<p>Applications 3-Iodobenzonitrile<br></p>

<p>Applications Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.<br>References Ahmad, I. et al.: Bioorg. Med. Chem. Lett., 23, 1322 (2013); Rhee, H. et al.: Bull. Kor. Chem. Soc., 32, 2391 (2011);<br></p>

<p>Applications Ethyl Cyano(ethoxymethylene)acetate is an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.<br>References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);<br></p>

<p>Applications 2-Fluorocinnamic acid, 98% (cas# 451-69-4) is a useful research chemical.<br></p>

<p>Applications N’-(4-Cyanobutyl)-N-(4-methoxybenzyl)-N’-methyl-N-2-pyridinyl-1,2-ethanediamine (cas# 109912-34-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Chlorophenylboronic acid is a useful research chemical, a useful reagent for Suzuki-Miyaura cross-coupling reactions.<br>References Savitha, B., et al.: J. Heterocycl. Chem., 55, 2277 (2018); Liu, K., et al.: Eur. J. Org. Chem., 34, 4769 (2018)<br></p>

<p>Applications Piperidin-4-one Ethylene Ketal is a derivative formed from the condensation of cyclohexanone.<br></p>

<p>Stability Moisture, Light Sensitive<br>Applications Used for derivatization, TLC and HPLC separation, and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2.<br>References Clin. Chim. Acta., 214, 195 (1993), Anal. Lett., 26, 429 (1993)<br></p>

<p>Applications 3-Bromo-2-cyanopyridine (cas# 55758-02-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An impurity of Atorvastatin.<br>References Graul, A., et al.: Drugs Fut. 22, 956 (1997),<br></p>

<p>Applications (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) (cas# 19249-03-7) is a useful research chemical.<br></p>

<p>Applications N,N-DIMETHYLFORMAMIDE DINEOPENTYL ACETAL (cas# 4909-78-8) is a useful research chemical.<br></p>

<p>Applications 3-Methoxybenzenethiol is a versatile reactant used in the preparation of sulfides by cuprous iodide catalyzed coupling with aryl iodides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kwong, F., Buchwald, S.: Org. Lett., 4, 3517 (2002);<br></p>

<p>Applications 2-Methyl-4-nitropyridine (cas# 13508-96-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Ethylethylenediamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl 4-Methoxyphenylacetate (cas# 23786-14-3) is a useful research chemical.<br></p>

<p>Applications An intermediate in the preparation of a potential inhibitor of GAR Tfase.<br>References Cheng, H. et al.: Bioorg. Med. Chem., 13, 3593 (2005)<br></p>

<p>Applications Intermediate in the preparation of Ertapenem (E635000).<br></p>

<p>Applications Triisopropyl Borate is a borate ester used in Suzuki couplings.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wolfe, J. et al.: J. Am. Chem. Soc., 121, 9550 (1999); Darses, S. et al.: Eur. j. Org. Chem., 8, 1875<br></p>