Building Blocks

<p>Applications 2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.<br>References Liu, J., et al.: Synthesis., 45, 943 (2013); Rambabu, D., et al.: Bioorg. Med. Chem. Lett., 23, 1351 (2013);<br></p>

<p>Applications An impurity of Atorvastatin.<br>References Graul, A., et al.: Drugs Fut. 22, 956 (1997),<br></p>

<p>Applications o-Isopropylaniline was used in the synthesis of a colorless amine-coordinated zinc complex.<br>References Li, D., et al.: Org. Biomol. Chem., 8, 1816 (2010)<br></p>

<p>Stability Air Sensitive<br>Applications A potent agonist at hOR17-4 (a human testicular olfactory receptor) and acts as a strong chemoattractant in sperm behavioral assays. The bourgeonal-hOR17-4 signaling pathway potentially governs chemical communication between sperm and egg and may be used to manipulate or block fertilization. Bourgeonal is an aromatic aldehyde used in perfumery. It has a fragrance reminiscent of lily of the valley, otherwise described as floral, watery, green and aldehydic. It is a pale yellow liquid at room temperature.<br>References Spehr, M., et al.: Science, 299, 2054 (2003)<br></p>

<p>Applications 4-Bromocinnamic Acid (cas# 1200-07-3) is a compound useful in organic synthesis.<br>References Patel, C., et al.: Bioorg. Med. Chem. Lett., 16, 4752 (2006), Ghorai, P., et al.: J. Med. Chem., 51, 7193 (2008),<br></p>

<p>Applications A useful synthetic intermediate. It is used as a reactant in synthetic preparation of chiral 2-carboxy cyclic ethers.<br>References Zhu, S., et al.: J. Am. Chem. Soc., 132, 16374 (2010);<br></p>

<p>Applications N-(2-Indanyl)aniline is a reagent that is used in the synthesis of Aprindine Hydrochloride (A729900), which is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies.<br>References Danilo, P. Jr., et al.: Am. Heart. J., 97, 119 (1979); Atarashi, H., et al.: Circulation. J., 66, 553 (2002);<br></p>

<p>Applications 4-​Hydroxy-​7-​methoxy-6-​quinolinecarboxamide​ is useful in the synthetic preparation of Lenvatinib (L329400(P)) with high purity. Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.<br>References Liu, S., et al.: Faming Zhuanli Shenqing (2020), CN 111377865 A; Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)<br></p>

<p>Applications 2-(Cyclopropylmethoxy-d4)-acetic Acid (cas# 1346602-05-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Acetamidine Hydrochloride (cas# 124-42-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Bromopropionitrile acts as a reagent in the preparation of bisindole maleimide derivative useful as α-glucosidase inhibitors for the treatment of diabetesis. Also used in the study of the structure activity relations between alkyl nucleophilic chemicals causing duodenal ulcer and adrenocortical necrosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Szabo, S., et al.: J. Pharm. Exp. Ther., 223, 68 (1982); Zhu, W., et al.: Faming Zhuanli Shenqing (2016); CN 106146487 A 20161123;<br></p>

<p>Applications 3-Methyl-3-(methylamino)butanoic Acid Methyl Ester is an derivative of substituted 3-pyrrolidinols with potential anticholinergic activities.<br>References Ryan, C.W., et al.; J. Org. Chem., 27, 2901 (1962);<br></p>

<p>Applications 8-Bromooctan-1-ol (cas# 50816-19-8) is a useful research chemical.<br></p>

<p>Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.<br>References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)<br></p>

<p>Applications (4-Fluorophenyl)hydrazine, HCl<br></p>

<p>Applications DI-Tert-Butyl Hydrazodicarboxylate (cas# 16466-61-8) is a useful research chemical.<br></p>

<p>Applications 1-​Bromododecane (n-Lauryl Bromide) is a reagent used in the synthesis of porous organic polymers.<br>References Zhao, Y. et al.: ACS Macro. Lett., 7, 300 (2018);<br></p>

<p>Applications N-Ethylethylenediamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Amino-5-bromo-4,6-dimethylpyridine (cas# 89856-44-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,5-DIMETHOXYTETRAHYDROFURAN (cas# 696-59-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Bromophenylacetic Acid (cas# 1878-68-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N,N-Dimethylmethyleneiminium Iodide (cas# 33797-51-2) is a useful research chemical.<br></p>

<p>Applications (±)-3-Heptanol, is a volatile components of various plants, and can be used as flavor and fragrance ingredients. It is also used as building block used for the synthesis of various chemicals. It is used for the preparation of biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, I., et al.: Bioorg. Med. Chem. Lett., 55 (18), 5889 (2012); Gibka, J., et al.: Zeszyty Naukowe - Politechnika Lodzka, 60, 65 (1998);<br></p>

<p>Applications N-(2-Bromoethyl)phthalimide is a building block that has been used as a reactant for the preparation of β-Cyclodextrin derivatives.<br>References Karginov, V.A., et. al.: Bioorg. Med. Chem., 14, 33 (2006)<br></p>

<p>Applications 2-Iodobenzyl Alcohol (cas# 5159-41-1) is a useful research chemical.<br></p>

<p>Applications Isobutyric Anhydride is used as a highly reactive and non-water producing acyl donor for hydrolase-catalyzed enantioselective esterification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, J.-H., et al.: Appl. Microbiol. Biot., 43, 402 (1995)<br></p>

<p>Applications (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) (cas# 19249-03-7) is a useful research chemical.<br></p>

<p>Applications 3-Iodobenzonitrile<br></p>

<p>Stability Hygroscopic<br>Applications N-methyl-2-phenylpropan-1-amine (cas# 93-88-9) is a useful research chemical.<br></p>

<p>Applications N-(Benzyloxycarbonyl)-4-piperidone<br></p>

<p>Applications Ethyl Cyano(ethoxymethylene)acetate is an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.<br>References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);<br></p>

<p>Applications Possess activity against positive phototaxis of Chlamydomonas cells.A fundamental starting material for organic synthesis.<br>References Evans, S., et al.: Chem. Biol. Drug. Des., 75, 333 (2010), Rajabi, L., et al.: Lett Appl Microbiol., 40, 212 (2005),<br></p>

<p>Applications 1-BROMOEICOSANE (cas# 4276-49-7) is a useful research chemical.<br></p>

<p>Applications Methyl β,β-Dimethoxypropionate is used as a reactant in the preparation of tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents.<br>References Zheng, C., et. al.: J. Med. Chem., 57, 600 (2014)<br></p>

<p>Applications 2-Bromopropionic Acid is a versatile reactant used in emulsion polymerization in the preparation of reversible addition-fragmentation chain transfer (RAFT) agent.<br>References Ferguson, C., et al.: Macromolecules, 35, 9243 (2002); Ferguson, C., et al.: Macromolecules, 38, 2191 (2005);<br></p>

<p>Applications Diethyl Butylethylmalonate-d5 is the isotope labelled analog of Diethyl Butylethylmalonate, a derivative of Diethyl 2-n-Butylmalonate (D443880) which is a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria.<br>References Yang, S., et al.: Eur. J. Med. Chem., 86, 133 (2014); Shi, W., et al.: Bioorg. Med. Chem. Lett., 20, 3592 (2010)<br></p>

<p>Applications 2-sec-Butylphenol is a substance used in checking the effect of different enhancers on transdermal permation of insulin. It also acts as one of the substances used as models, which are helpful for aiding screening and development of androgenic compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yerramsetty, K. M., et al.: Int. J. Pharm., 398, 83 (2010); Jia, Y., et al.: isuanji Yu Yingyong Huaxue, 24, 1469 (2007)<br></p>

<p>Applications 4-Methoxy-3-nitrobenzoic acid is a substituted nitrobenzoic acid reagent for proteomics and organic synthesis research.<br>References Achary, R. et al.: Bioorg. Med. Chem. Lett., 27, 2185 (2017);<br></p>

<p>Stability Moisture Sensitive<br>Applications 10-Bromodecanol can be used to synthesize rotaxane dendrimers. It can also be used to synthesize J2326, a molecule that induces neurite outgrowth in neuronal cells.<br>References Wei, W., et al.: Proc. Natl. Acad. Sci. USA 112, 5597 (2015); Chang, P., et al.: Neuropharmacology 92, 146 (2015)<br></p>

<p>Applications Intermediate in the preparation of Ertapenem (E635000).<br></p>

<p>Applications is a building block used in various chemial synthesis such in the preparation of 6-(carboxymethylureido)-(±)-nicotine (CMUNic), nicotine immunogen, and  imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione.<br>References Y Hieda et. al,: The Journal of pharmacology and experimental therapeutics, 283(3), undefined (1998-2-12); Papadopoulos EP.Journal of Heterocyclic Chemistry 18(3), 515-518,<br></p>

<p>Applications (E)-3-Hexenoic Acid is a useful organic reagent. It was used to design optically active selenium reagents with a chiral tertiary amino groups. It is a side-chain for penicillin F (CAS# 118-53-6).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujita, K., et al.: Tetrahedron, 53, 2029 (1997);<br></p>

<p>Applications An intermediate in the preparation of a potential inhibitor of GAR Tfase.<br>References Cheng, H. et al.: Bioorg. Med. Chem., 13, 3593 (2005)<br></p>