Building Blocks

<p>Applications Anisole-2,4,6-d3 (CAS# 2567-25-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3,5-Dimethoxybenzaldehyde, is a benzaldehyde derivative, that can be used as a building block in the synthesis of more complex structures.<br>References Frouz, J., et al.: Biodegredation., 22, 1247 (2011); Garcia-Carpintero, E., et al.: Food. Res. Int., 44, 61 (2011);<br></p>

<p>Applications 4-Chlorophenyl Phenyl-d5 Ether (CAS# 93951-85-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Nε-Boc-D-lysine is an N-Boc-protected form of L-Lysine (L468895). L-Lysine is an essential amino acid for humans, with a suggested intake of 5-8 grams per day. L-Lysine can be found in a variety of food, such as eggs and quinoa, but is also mass produced by microbial fermentation. L-Lysine is also used as therapy to treat recurrent herpes simplex infections.<br>References Anastassiadis, S.: Biotechnology, 1, 11 (2007); Civitelli, R., et al.: Nutrition, 8, 400 (1991); Griffith, R., et al.: Dermatology, 175, 183 (1987)<br></p>

<p>Applications Dimethyl Hexanedioate-3,3,4,4-d4 (CAS# 55724-08-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Dimethyl Hexanedioate-d8 (CAS# 52089-64-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Anisole-2,3,4,5,6-d5 (CAS# 50629-14-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-Chloro-1-hexene is a reagent with difluoroacetic acid that results in the formation of 5-chloro-2-hexyl-2-d trifluoro-acetate and 1,4-chlorine shift.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peterson, P. E., et al.: J. Am. Chem. Soc., 86, 4503-4 (1964)<br></p>

<p>Applications 2,4-Dichloro-5-bromopyrimidine (cas# 36082-50-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Bromo-1-pentene (cas# 1119-51-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Bromooctadecane-d37 (CAS# 187826-28-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Anisonitrile (cas# 874-90-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Enoxacin intermediate.<br>References Hinman, M., et al.: J. Med.l Chem., 49, 4842 (2006), Kumar, V., et al.: J. Enz. Inhib. Med. Chem., 24, 1169 (2009),<br></p>

<p>Applications 1-Bromooctadecane-18,18,18-d3 (CAS# 349553-85-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications α,α-Dichlorodiphenylmethane is a degradation product of polychloroaromatic insecticides such as Dicofol (D436700) and DDT. α,α-Dichlorodiphenylmethane is also used as a catalyst for photodegradation of plastics.<br>References Golovleva, L.A. et al.: Mikrobiologiya, 51, 973 (1982); Freedman, B.: J. Appl. Polym. Sci., 20, 911 (1976);<br></p>

<p>Applications 1,4-Dibromo-2-methylbenzene<br></p>

<p>Applications 4-ethyl-3-methyl-1H-pyrazol-5-amine (cas# 151521-79-8) is a useful research chemical.<br></p>

<p>Applications 1-Bromopentane-4,4,5,5,5-d5 (CAS# 83418-34-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Eicosanoic-2,2-d2 Acid (CAS# 232600-70-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Dibromo-5-fluorobenzene-d3 (CAS# 1219805-87-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentane-1-d1 (CAS# 148404-92-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Dichloropropene-d4 (cis/trans mixture) (CAS# 202656-23-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-Lysine-4,4,5,5-d4-bis-N-t-BOC (CAS# 1314753-85-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromo-2,3-dichlorobenzene-d3 (CAS# 1219805-59-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-Valine-d8-N-t-BOC (CAS# 153568-33-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentane-1,1-d2 (CAS# 77734-75-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications alpha,alpha'-Dibromo-p-xylene-d8 (CAS# 74903-77-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Cyano-4'-n-pentyl-d11-biphenyl (CAS# 57078-20-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Chloro-2-methylphenol-3,5,6-d3,OD (CAS# 1219804-06-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications BPTES is a potent and selective Glutaminase inhibitor. Used in the treatment of renal cell carcinomas resulting from overexpression of the MYC oncogene.<br>References Shroff, E. et al.: PNAS. U.S.A., 112, 6539 (2015); Thomas, A. et al.: Biochem. Biophys. Res. Comm., 443, 32 (2014);<br></p>

<p>Applications 4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.<br>References Terzioglu, N., et. al.: Bioorg. Med. Chem. Lett., 14, 5251 (2004)<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications Used in the preparation of herbicides.<br></p>

<p>Applications Potassium Hexadecanoate-d31 (CAS# 63074-47-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Potassium Octadecanoate-d35 (CAS# 352438-89-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Heptanoic-2,2-d2 Acid (CAS# 64118-38-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Heptanoic-5,5,6,6-d4 Acid (CAS# 352431-36-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications NS 9283 is a positive allosteric modulator of α4β2 receptor affecting the potency of acetylcholine (Ach) related events. This has been linked to affect on everyday brain function including cognitive function and pain alleviation.<br>References Olsen, J. et al.: J. Biol. Chem., 288, 35997 (2013); Marotta, C. et al.: ACS Chem. Biol., 9, 1153 (2014);<br></p>