Building Blocks

<p>Applications 2-methyl-2-(morpholin-4-yl)propanoic Acid hydrochloride (cas# 375397-37-8) is a useful research chemical.<br></p>

<p>Applications methyl 3-(4-methylbenzenesulfonamido)benzoate (cas# 173436-66-3) is a useful research chemical.<br></p>

<p>Applications Misonidazole can be used as a potential hypoxic cancer cell radiosensitizer and DNA binding and nicking agent. The metabolites of misonidazole can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells<br>References Bonnet, M., et al.: Bioorg. Med. Chem., 22, 2123 (2014); Edwards, D.I.: Comprehensive Med. Chem., 2, 725 (1990); Murata, R., et al.: Radiother. Oncol., 87, 331 (2008); Brown, J.M. The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles. Int.J.Radiat.Oncol.Biol.Phys. 8(3-4), 675-682 (1982).<br></p>

<p>Applications Methylcyclohexane-D14 (D, 99.5%) (cas# 10120-28-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Methylbenzamide (cas# 618-47-3) is a useful research chemical.<br></p>

<p>Applications Mono-tert-butyl Malonate is a useful synthetic intermediate. It can be used to prepare quinoline-based zinc metallo-aminopeptidase inhibitors with antimalarial activity. It can also be used to synthesize truncated aminoglycoside-CoA bisubstrate analogs via chemo- and regioselective coupling reaction of amine and thiols, as inhibitors of aminoglycoside 6'-N-acetyltransferase Ii<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Flipo, M., et al.: Bioorg. Med. Chem. Lett., 13, 2659 (2003); Gao, F., et al.: J. Med. Chem., 49, 5273 (2006)<br></p>

<p>Applications Mono-tert-butyl Malonate-(N-Boc)-L-lysine is an intermediate used in the synthesis of N6-(2-Carboxyacetyl)-L-lysine (C178063), which is a malonylated conjugate of L-Lysine (L468895) essential amino acid.<br>References Tosha, L. et. al.: Biochem. J., 435, 509 (2011); Peng, C., et al.: Mol. Cell. Proteomics, 10, 012658/1 (2011);<br></p>

<p>Applications m-Toluidine-d7 (NH2) (CAS# 68408-25-3) is a useful isotopically labeled research compound. Due to the H-D reaction, this compound can be used as a mixed catalystic for its synergistic effect.<br>References Ito, N., et.al., Synthesis, 9, 1467-1478,(2008);<br></p>

<p>Applications Monoethyl Potassium Malonate, is a derivative of Malonate, which is a competitive inhibitor of the enzyme succinate dehydrogenase. It binds to the active site of the enzyme without reacting, and so competes with succinate, the usual substrate of the enzyme.<br>References Potter, V. R., et al.: J. Gen. Phys., 26, 391 (1943);<br></p>

<p>Applications Monomethyl Glutarate, is a building block used in various chemical synthesis.<br></p>

<p>Applications 2-Methyl-4,5,7-trichloroquinoline (cas# 203626-80-6) is a useful research chemical.<br></p>

<p>Applications 4-Morpholine-d8-carbonyl Chloride (CAS# 1219804-24-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-(N-Morpholino)propanesulfonic Acid-d15 (CAS# 1219799-30-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications m-Xylene-d4 (ring-d4) (CAS# 425420-97-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Methyl-d3-propyl Alcohol (CAS# 95927-04-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Methylpropyl-2-d1 Alcohol (CAS# 20440-13-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Methyl 3-hydroxy-4,5-dimethoxybenzoate (cas# 83011-43-2) is a useful research chemical.<br></p>

<p>Applications trans,trans-Muconic-d4 Acid (CAS# 1955496-83-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,4,4-Trimethyl-2-oxazoline is a useful building block and has been used in the preparation of imides by ring opening of heterocycles by reactions of acyl palladium species.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Perrone, S.; et al.: Tetrahedron, 70, 6938 (2014).<br></p>

<p>Applications Tetradecanoic-2,2-d2 Acid (CAS# 30719-21-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetradecanoic-14,14,14-d3 Acid (CAS# 62217-71-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetradecanoic-12,12,13,13,14,14,14-d7 Acid is a useful isotopically labeled compound of Myristic Acid (M884610)<br></p>

<p>Applications Myristyl Palmitate is a wax ester of palmitic acid. Wax esters are esters between long chained fatty alcohols and fatty acids. Wax esters have significance in pharmaceutical and cosmetics applications and occur naturally in plants and animals.<br>References Wheatley, V., et al.: Biochem. J., 58, 167 (1954); Shichijo, S., et al.: Biochem. Med., 22, 256 (1979); Robosky, L., et al.: J. Lipid Res., 49, 686 (2008);<br></p>