Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-(1H-Imidazol-1-yl)benzoic acid is a heterocyclic organic compound that is used as an excitatory neurotransmitter. It has a high affinity for the metabotropic glutamate receptor and is able to induce excitatory postsynaptic potentials in neurons. 3-(1H-Imidazol-1-yl)benzoic acid binds to the postsynaptic membrane and blocks the ion channels, leading to depolarization of the neuron membrane. The glutamate binding site on the metabotropic glutamate receptor is low nanomolar and five membered, making it a competitive antagonist at this site.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Aminomethyl)-4-chloroaniline is an organic compound that can be synthesized in a sustainable manner. It has been used as an additive for the oxidation of benzyl amines with transition metal catalysts. 2-(Aminomethyl)-4-chloroaniline is also a reagent for the synthesis of quinazoline derivatives and quinazolines. The efficiency of this process has been shown to increase with the substitution of n-substituted benzylamines.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(1S)-1-(2-Methoxyphenyl)ethan-1-ol is a synthetic intermediate that belongs to the class of alcohols. It has been shown to be an enantioselective hydrogenation substrate for the transfer hydrogenation of acetophenones. The compound can also be used in biological synthesis and organic synthesis as a chiral, optically pure building block.</p>

<p>The compound 2-oxo-1H,2H,5H,6H,7H-cyclopenta[b]pyridine-3-carbonitrile is a heterocyclic compound that belongs to the class of tricyclic compounds. It has an anisotropic crystal system and a single crystal x-ray diffraction pattern. The molecular geometry of this compound is a trigonal planar with three atoms in the plane. The molecular weight of 2-oxo-1H,2H,5H,6H,7H-cyclopenta[b]pyridine-3-carbonitrile is 205.08 g/mol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

2-Methyl-5-phenylfuran-3-carboxylic acid (2MPFC) is a ligand that binds to the agonist binding site of the 5HT1A receptor. It has been shown to have potent effects on red blood cells, cell function and Alzheimer’s disease. 2MPFC has been shown to activate microglial cells and increase blood pressure in some models. The compound activates the receptor by binding it in an allosteric manner, which is a different mechanism than other ligands that bind at the orthosteric site. This compound also has been shown to be able to reduce dehydration and increase water intake in mice.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

6-(Benzyloxy)quinoline is a quinoline derivative that is structurally related to trehalose and covalently binds to anilines. It has been shown to selectively inhibit kinases, such as protein kinase A and protein kinase C, with pyridinium and quinolinium as the major metabolites. The compound has been isolated in good yield from betaine and carbodiimides. 6-(Benzyloxy)quinoline has also been found to be amine-labeling reagent for amines, which can be used in bromoacetic acid labeling of proteins.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,3-Dihydro-1H-indole-2-carboxamide is a synthetic peptidomimetic that inhibits NS3 protease, which is involved in the viral life cycle. 2,3-Dihydro-1H-indole-2-carboxamide has been shown to have potent inhibitory activity against the hepatitis C virus (HCV) and HIV. It also inhibits the replication of HCV in mammalian cells. This drug has pharmacokinetic properties that are similar to glibenclamide and penetrates the blood brain barrier. Clinical studies have been conducted on patients with chronic hepatitis B and C infection.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dibromo-4-methoxybenzaldehyde is an aromatic compound with a hydroxy group. It has antibacterial activity against the ascidian and Staphylococcus aureus. The nanoribbons of 3,5-Dibromo-4-methoxybenzaldehyde are synthesized from the hydroxyl group of 3,5-Dibromo-4-methoxybenzaldehyde. The kinetic and fluorescent properties of this compound have been studied and found to be similar to those of other quinones.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Naphthalen-1-yl)benzoic acid is an experimental compound that has shown supercooling properties. It is a nonplanar molecule, which may account for its high heat capacity. This compound also has the ability to entrap other molecules in its crystal lattice and can be used for the removal of impurities from organic solvents. 2-(Naphthalen-1-yl)benzoic acid has been used as a kinetic probe to study transport mechanisms, analytical methods, and kinetics of chemical reactions. It has also been studied in relation to the mathematical analysis of molecular motion and molecular interactions in solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>