Building Blocks

<p>Versatile small molecule scaffold</p>

<p>1-(3-Furyl)methanamine hydrochloride is a halogen compound that causes severe contact dermatitis. It has been shown to cause ischemia injury in the rat heart by attacking selenides and chalcogenides. 1-(3-Furyl)methanamine hydrochloride also induces acute myocardial infarction in rats, which may be due to its ability to induce oxidative stress and inhibit the production of nitric oxide. This compound also increases the susceptibility of animals to heart attack induced by sulfide or halogen.</p>

<p>5-(Chloromethyl)thiazole hydrochloride (5-CT) is a dopamine transporter inhibitor that is used in research of the dopamine system. This drug binds to the dopamine transporter, thereby blocking dopamine reuptake and prolonging the action of dopamine in synapses. 5-CT has been shown to increase motivation and impair cognitive function, which may be due to its ability to increase dopaminergic neurotransmission.<br>5-CT is also used as a probe for the study of other neurotransmitter systems such as serotonin, norepinephrine, and acetylcholine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(1H-Pyrrolo[3,2-b]pyridin-3-yl)-1,2,3,6-tetrahydropyridine (4-PPT) is a serotonergic receptor agonist that belongs to the class of pyrrolopyridines. It has shown affinity for 5-HT1A and 5-HT1B receptors in biochemical and behavioral studies. 4-PPT has been found to produce hyperlocomotion in rats with a dose of 2mg/kg. 4-PPT also increases the affinity of serotonin for the 5HT1B receptor by inhibiting an unknown protein kinase C isoform. The binding of serotonin at this site is thought to be responsible for its antihypertensive effects.</p>

<p>Versatile small molecule scaffold</p>

<p>5-[(4-Nitrophenyl)methyl]-1H-1,2,3,4-tetrazole is a transition metal complex that has been shown to be catalytic. The crystal x-ray diffraction pattern of the compound shows that it has a crystallographic space group of P2/c, with unit cell dimensions of a = 17.94 Å and c = 9.66 Å. The molecular geometry is trigonal planar with dihedral angles of 18.6° between the nitro group and the methylene group on one side and 16.5° between the methylene group on the other side. The crystal structure consists of two benzene molecules bridged by 2 nitro groups and 1 methylene group in an octahedral geometry.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(3-Chloropyridin-2-yl)ethanone is an antibacterial agent that belongs to the group of organochlorine compounds. It has a bactericidal and bacteriostatic effect on a number of microorganisms, including bacteria, fungi, protozoa, and viruses. 1-(3-Chloropyridin-2-yl)ethanone is used in preparations for the treatment of wounds and skin infections as well as for disinfecting the environment. The active substances in 1-(3-Chloropyridin-2-yl)ethanone are bactericidal and bacteriostatic against a broad spectrum of microorganisms. These substances are also effective against some strains that develop resistance to antibiotics.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Hydroxy-6-Thioxo-1,6-Dihydropyridine-2-Carboxylic Acid is a cellular modulator that acts as a regulator of gene expression. It is an inhibitor of the myotonica chloride channel and inhibits the activity of target enzymes by binding to their active site and blocking them from performing their function. 1-Hydroxy-6-Thioxo-1,6-Dihydropyridine-2-Carboxylic Acid has been shown to be effective in controlling cardiac hypertrophy and preventing heart failure. The molecule also targets ribosomes, which are involved in protein synthesis. This drug has low expression levels in cells and is not very cell culture labile. 1HTCA binds to the ribosome and prevents protein synthesis by inhibiting peptidyl transferase activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-formyl-3-hydroxybenzoate is a formylating agent that reacts with the hydroxyl group of benzene to form a methyl ester. It has been used in the production of polyphosphoric acid, and is also used in the synthesis of salicylic acid and other organic compounds. Methyl 2-formyl-3-hydroxybenzoate reacts with hexamethylenetetramine to produce hexamethylenetricarboxylic acid, which can be reacted with an alcohol to produce an ester. This reagent has been shown to have antifungal activity against Rhizoglyphus sp.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>