Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Cyclopentyl-N-propylamine is a functional compound that belongs to the class of organic compounds. It is used as an intermediate in the synthesis of other drugs and pharmaceuticals. This compound has been shown to have a high reactivity, which makes it useful in polymerization and polymerization initiator applications. N-Cyclopentyl-N-propylamine has been shown to be reactive with polarizers, alkylthio groups, and trifluoromethyl groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Bis(3-methoxyphenyl)methanone is a palladium catalyst that selectively activates olefins. It has been shown to be useful in the synthesis of dihydrobenzofurans and oxonium derivatives, which are used as pharmaceuticals. This compound also catalyzes the transformation of various functional groups, such as diazo, alkenes, and intramolecular aldol condensation. Bis(3-methoxyphenyl)methanone is used as a catalyst for the production of dibenzofuran compounds with high selectivity. The diastereoselectivity of this compound is due to its ability to activate substrates with electron-donating groups at positions ortho to the phenyl group.</p>

<p>Versatile small molecule scaffold</p>

<p>3,3-Dimethyl-1-(methylsulfanyl)butan-2-one is an enolate that is used as a pesticide. It is typically applied to the soil or sprayed on plants. It can be modified to increase its insecticidal activity by adding other chemicals such as carbaryl, acetonitrile, or hydroxymethylphenyl. 3,3-Dimethyl-1-(methylsulfanyl)butan-2-one is metabolized by hydrolysis and methylcarbamates are formed. The sulfide group in the molecule reacts with oxygen to form sulfoxides and carbofuran, which are toxic to mammals and birds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Ethylamino-1-butanol is an alkanolamine that interacts with receptors in the body. It has a hydroxyl group and is a molecule that contains functionalities. It interacts with other molecules, such as corticotropin-releasing hormone (CRH). 4-Ethylamino-1-butanol binds to CRH and prevents it from binding to its receptor, which decreases the release of corticotropin. This compound has been used as a positron emission tomography (PET) radiotracer for imaging the insulin receptor in living tissue. The chemical can be systematically introduced into tissues and organs, including the brain, where it accumulates due to its hydrophilic nature. 4-Ethylamino-1-butanol also has oxygenated groups that are suitable for PET imaging using 18F radiolabeling.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Nitro-1,2,3,4-tetrahydroquinoline is an amine that is used in the synthesis of other chemicals. It is selective for transfer reactions because it can transfer to sulfate. The reaction selectivity is determined by the module and the reaction solution. The efficiency of the carbenium ion can be increased by adjusting the pH to make it more acidic. 5-Nitro-1,2,3,4-tetrahydroquinoline has a high yield and can be synthesized with a high degree of purity by using ammonium sulfate as a transfer agent in a neutral solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Dichloro-2-nitrophenol is a chemical that is used as an immunomodulator, pesticide, or herbicide. It is activated by the body to form a reactive intermediate that can bind to DNA and create mutations. 5-Dichloro-2-nitrophenol has been shown to cause oxidative damage in cell cultures and other tissues, such as proximal tubules of the kidney. It also produces malondialdehyde oxidation products which are known to be cytotoxic. In addition, preincubation with 5-Dichloro-2-nitrophenol increases the sensitivity of cells to other oxidative stressors such as peroxides and hydrogen peroxide.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-N-Benzyl-4-chlorobenzene-1,2-diamine is a chemical compound that is used as an anticancer drug. It is a potent inhibitor of protein kinase C and has been shown to induce cell cycle arrest in the G1 phase of the cell cycle. 1-N-Benzyl-4-chlorobenzene-1,2-diamine also induces apoptosis in cancer cells. The cytometric analysis of apoptotic processes was used to determine the pharmacokinetic properties of 1-N-Benzyl-4-chlorobenzene-1,2-diamine. This drug may be mediated by annexin A5 or other proteins. Radionuclide imaging studies were conducted in order to assess the pharmacokinetics of 1NBDBCD in humans.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 4-sulfanylbutanoate is a leukotriene D4, which is an inflammatory mediator. It can be activated by the addition of hydrogen peroxide or tetrahydropyran and then becomes a potent leukotriene antagonist. Methyl 4-sulfanylbutanoate also inhibits the activity of acyltransferases, which are enzymes that catalyze reactions in the synthesis of arachidonic acid. This compound has been shown to have inhibitory effects on inflammatory bowel disease and may be useful for treating cerebral inflammation.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromocyclooctan-1-one is a chiral, fluorinated ketone that has been used as a reagent in conformational studies. It is also the precursor to other compounds of interest. 2-Bromocyclooctan-1-one reacts with thioacetamide to form an intermediate that can be hydrolyzed by water or acid to produce 2,4,6-trichlorobenzene sulphonyl chloride. In acetonitrile, it displays repulsion between the two bromine atoms. The conformation of this compound is dependent on solvent and conformational studies have been done using solvents such as acetonitrile and chloroform.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 3-acetyl-4-oxopentanoate is a synthetic porphyrin precursor. It is an isomer of hematoporphyrin, which has been shown to be an effective photosensitizer for the treatment of psoriasis. Methyl 3-acetyl-4-oxopentanoate has also been shown to have degradative properties, and can be used to synthesize pyrrole compounds. This synthetic porphyrin precursor can also be used in the production of other porphyrins such as protoporphyrins and porphyrins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>