Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylbenzamide oxime is a chemical compound that has the chemical formula C6H5N3O. It is used as a reagent in organic synthesis. 3-Methylbenzamide oxime also acts as a silver-containing oxidant, which can be used to generate hydrogen peroxide or silver oxide.</p>

<p>N-Hydroxymethyl-3-(trifluoromethyl)benzamide is an oxidative and reductive elimination agent that can be used in a variety of synthetic reactions. This compound can be used to synthesize hydroxamic acids, alkenylations, carboxylates, and other functionalized organic compounds. This compound is also useful for the preparation of aromatic carboxylic acid derivatives. The mechanism for this reaction is the hydroxamic acid formation through reductive elimination followed by the addition of an alcohol or amine. The reaction begins with the oxidative cleavage of an ester or amide bond to form a carbonyl group and a hydroxylamine moiety. The hydroxylamine then undergoes reductive elimination to yield a hydroxamic acid. This process is catalyzed by metal ions such as copper (Cu), zinc (Zn), and iron (Fe).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methylquinoline-2-carboxaldehyde is a formylating agent that is used in the synthesis of heterocycles. It has been shown to react with methanol and mediated by oxidative conditions to produce formaldehyde. This reagent can be used for the functionalization of biomolecules by reacting with amines, thiols, and hydroxyl groups. 4-Methylquinoline-2-carboxaldehyde can also be used for the oxidative coupling of phenols and naphthols. The functional group on this compound is a carboxylic acid (-COH).</p>

<p>8-Thia-4,6-diazatricyclo[7.5.0.0,2,7]tetradeca-1(9),2(7),5-trien-3-one is a synthetic antifungal molecule with inhibitory properties against the growth of fungi. This compound inhibits the biosynthesis of ergosterol, an essential component of the fungal cell membrane, by inhibiting the enzyme squalene epoxidase. 8-Thia-4,6-diazatricyclo[7.5.0.0,2,7]tetradeca-1(9),2(7),5-trien-3-one has been shown to be effective in killing Candida albicans and other species of pathogenic fungi in cell culture and animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-5-one (6,7-DHP) is a muscarinic acetylcholine receptor agonist that has been shown to have profiles of both an agonist and antagonist. It was discovered by screening compounds against the acetylcholine receptor in the presence of different concentrations of acetylcholine. 6,7-DHP activates the receptor at low concentrations and inhibits it at higher concentrations. 6,7-DHP is used as an experimental tool to investigate the function of the muscarinic acetylcholine receptor in various diseases such as psychiatric disorders and inflammatory diseases. The molecule also has potential therapeutic applications for these disorders.</p>

<p>1H,2H,3H-pyrrolo[3,4-c]pyridin-3-one is a phosphoinositide synthesis inhibitor. It is an important drug target for the treatment of cancer due to its ability to inhibit the production of phosphoinositides that are necessary for the regulation of cell growth, proliferation and differentiation. The therapeutic potential of 1H,2H,3H-pyrrolo[3,4-c]pyridin-3-one has been demonstrated through chemistry studies and medicinal chemistry approaches. This molecule was synthesized with a 3-kinase inhibitor moiety and a reactive carboxamides group.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2,3-Dihydro-1H-indol-3-yl)ethan-1-ol is a crystalline compound that can be prepared by the addition of hydrogen chloride to 2-(2,3-dihydroindol-3-yl)ethanol. It is an enantiomer of 1-(2,3-dihydroindol-3-yl)ethanone. The compound has been used as a reagent in analytical chemistry and as a substrate for oxidases and other enzymes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Diethyl (methylsulfonylmethyl)phosphonate is a synthetic compound that has been shown to inhibit the mineralocorticoid receptor. This receptor is involved in the regulation of electrolyte and fluid balance. The inhibition of this receptor by diethyl (methylsulfonylmethyl)phosphonate may be due to its ability to bind to the receptor's active site and prevent it from binding with other hormones, such as aldosterone. Diethyl (methylsulfonylmethyl)phosphonate also has antiviral and anti-cancer properties. It can inhibit the proteolytic activity of a virus, such as hepatitis, or protease enzymes found in cancer cells. Diethyl (methylsulfonylmethyl)phosphonate can also act as an allergen for some people and cause skin irritation.</p>

<p>2,2-Dimethyl-1,3-dioxan-5-amine is an organic molecule that utilizes electron affinity to synthesize with a variety of orientations. The hydrophobic and intramolecular orientations are the most common. The 2,2-dimethyl-1,3-dioxan-5-amine molecule has been shown to be capable of utilizing the hydrogen atom in water as an electron acceptor and donor. It can also form a monolayer on a gold electrode surface. This molecule is hydrophilic and therefore prefers hydrophilic environments such as the electrode surface or water. Impurities in this compound may include fluoride ion or chloride ion.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Iodo-1,3-dimethyluracil (5IDMU) is a nucleoside that is used in cancer diagnosis. 5IDMU can be synthesized by the Suzuki coupling reaction with an amine and a halide. The synthesis of 5IDMU can also be accomplished by the cross-coupling of an amine and a tautomeric methylene compound. The methylene group in the heterocycle is electron donating, which makes it more reactive than other groups. This nucleoside has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. 5IDMU has also been shown to have anticancer effects in vitro and in vivo.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(4-Bromophenyl)-1,2,3-thiadiazole is a mediated drug that belongs to the class of retinoids. It has been shown to have anticancer activity in vitro and in vivo. 4-(4-Bromophenyl)-1,2,3-thiadiazole is an endogenous metabolite of all-trans-retinoic acid (ATRA), which is a molecule synthesized from vitamin A. This drug also inhibits cytochrome p450 enzymes and can be used as an antidote for poisoning by itraconazole and other drugs that inhibit the same enzyme system.</p>

<p>Versatile small molecule scaffold</p>

<p>Bis(1,5-cyclooctadiene)(duroquinone) nickel(0) is a synthetic compound that belongs to the class of organometallic compounds. It is used as a ligand in cross-coupling reactions and as a catalyst in organic synthesis. Bis(1,5-cyclooctadiene)(duroquinone) nickel(0) has been shown to react with Grignard reagents and boronic acids to form complex molecules with stereospecificity. This compound also reacts with aldehydes and triflates to form alkenylation products. The mechanism for this reaction is not well understood, but it is thought that the bis(1,5-cyclooctadiene)(duroquinone) nickel(0) binds to the electrophilic carbon atom of the carbonyl group through its duroquinone moiety and then undergoes oxidative addition with the Grignard reagent</p>

<p>Versatile small molecule scaffold</p>

<p>1,5-Dihydroxy-1,2,3,4-tetrahydronaphthalene is an experimentally studied chemical compound. It has been studied for its ability to catalyze the transesterification of vinyl acetate and tetrahydrofuran. This reaction is a good example of a ternary catalyst that is operational under both kinetic and optimal conditions. 1,5-Dihydroxy-1,2,3,4-tetrahydronaphthalene is also an enantiomeric mixture with a selectivity of the order of 90% for the (S)-enantiomer.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2-Aminoethyl)imidazolidine-2-thione is a hydrocarbon that inhibits corrosion by binding to metal ions and preventing the formation of corrosion products. It has been shown to be a potent inhibitor of corrosion in water, with more than 50% inhibition at pH 7.1. 1-(2-Aminoethyl)imidazolidine-2-thione has been shown to inhibit the deprotonation of thiourea in acidic conditions, which is an important step in the corrosion process. In addition, 1-(2-Aminoethyl)imidazolidine-2-thione binds to metal ions via its electron donor group and prevents the formation of anions. The molecular structure consists of a heterocyclic ring with five members, with the nitrogen atom occupying one position on the ring. As such, it can be classified as a heterocyclic amine or imidazolidineth</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>