Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Amino-3-chloropyridine-2-carboxylic acid (4ACPC) is an herbicide that has been used to control weeds in rice fields, sugar cane, and other crops. 4ACPC inhibits the growth of plants by inhibiting photosynthesis. It binds to the electron transport system in chloroplasts and reduces the amount of ATP available for use. This leads to a decrease in chlorophyll production and photosynthetic activity, which ultimately causes plant death. 4ACPC also binds to DNA and has been shown to inhibit transcription in calf thymus cells.</p>

<p>Versatile small molecule scaffold</p>

<p>(1R)-1-[4-(trifluoromethyl)phenyl]ethan-1-ol is a chiral alcohol that is used as a catalyst in organic synthesis. It reacts with many types of compounds, including choline, to produce the corresponding ester or amide. The reaction time is typically less than an hour, and the substrate concentration can be scaled up to 100 grams per liter. (1R)-1-[4-(trifluoromethyl)phenyl]ethan-1-ol is soluble in solvents such as benzene and chloroform. This compound has been shown to have chemokine activity against human monocytes and T lymphocytes.</p>

<p>(R)-1-(4-Bromophenyl)ethanol is a reactive chemical that has been shown to be enantiopure and have a high degree of purity. It can be used in microscopy to detect the presence of bacteria, as well as in biological properties studies. The compound is an isomer of (S)-1-(4-bromophenyl)ethanol and can be chiral or racemic. (R)-1-(4-Bromophenyl)ethanol has been sequenced and found to have a molecular weight of 156.2 g/mol. It also has a melting point of 78°C and a boiling point of 201°C. This compound's fluorescence emission maxima are at 400 nm and 440 nm, with an extinction coefficient of 100,000 M-1cm-1 at 400 nm. The compound's sigmoidal curve can be seen in the graph below:</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Tcpobop is an enzyme inducer that increases the metabolic rate and alters lipid metabolism. It has been shown to up-regulate genes involved in energy metabolism, such as fatty acid synthase, and genes involved in iron homeostasis, such as hepcidin. Tcpobop also inhibits cellular growth by causing cell cycle arrest at G1 phase and inducing apoptosis. Tcpobop enhances the expression of epidermal growth factor receptor (EGFR) in CD-1 mice. This may be due to its effects on protein synthesis and gene transcription.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(1R)-1-(3-Nitrophenyl)ethanol is a prochiral alcohol that is generated by the oxidation of nitrobenzene. It has an optimal pH range of 5.5-7.0 and optimum catalytic activity at a ph range of 6.5-8.0. (1R)-1-(3-Nitrophenyl)ethanol can be used in the production of antibiotics such as penicillin and cephalosporin, which are derived from erythromycin. The chiral nature of this molecule allows for the synthesis of two different stereoisomers: erythromycin A and erythromycin B. This molecule also has been shown to have antifungal properties, inhibiting the growth of bacteria such as Bacillus subtilis, Staphylococcus aureus, and Escherichia coli.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-4-(tribromomethyl)benzene (1,2,3,4-Tetrabromobenzene) is a perfluorinated chemical substance that is used in the manufacture of fluoropolymers. It is also used as an industrial chemical intermediate and as a precursor to other perfluorinated substances. 1,2,3,4-Tetrabromobenzene has been monitored by China and classified as a high priority for monitoring due to its potential for long-range environmental transport. The efficiency of screening for 1,2,3,4-Tetrabromobenzene in soil samples was found to be dependent on the extraction time and the extraction solvent. Organic chemicals such as 1,2,3,4-Tetrabromobenzene are screened for using gas chromatography with electron capture detection or liquid chromatography with tandem mass spectroscopy.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>SCH 28080 is a potent inhibitor of transcriptional activator protein-1 (AP-1) and nuclear factor-κB (NF-κB). These two transcriptional regulatory proteins are activated by various stimuli, including inflammatory cytokines, such as IL-1β, TNF-α, and IL-6. Activation of these transcription factors leads to the upregulation of the genes encoding proinflammatory mediators, such as eosinophil cationic protein and interleukins. SCH 28080 has been shown to inhibit NF-κB activation in human HL60 cells, which may be due to its ability to bind to both the α subunit of NF-κB and AP-1.</p>

<p>1,4-Dihydroquinoline-4-thione is an antibacterial agent that belongs to the class of thiourea derivatives. It has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. The crystal structure of 1,4-dihydroquinoline-4-thione was determined using X-ray crystallography techniques and gold nanoparticles. The compound has a hydroxyl group that can be labeled with several different groups to produce a variety of isomers.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(Pyridin-3-ylmethyl)-1H-1,3-benzodiazol-2-amine is a drug product that has been custom synthesized for a laboratory or research use. It has been purified to high purity and is suitable for analytical studies. It has been shown to be metabolized in vivo in humans and animals and is an impurity standard used for HPLC analysis. This compound may also be used as an API impurity or as a research and development chemical intermediate.</p>