Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-o-Tolyloxy-propionic acid (3TP) is a monomer that can be used in the production of polymers. 3TP has been shown to have high emission efficiency, which is attributed to its low density and inductive properties. It also has a low melting point, making it suitable for use in the production of polymers at low temperatures. 3TP is also known to have an acid group and vinyl group, making it useful in the production of polymers with a variety of functions. 3TP is soluble in water and other solvents, making it easy to handle during polymerization processes. It is non-toxic and environmentally friendly because it does not emit any harmful substances when heated or mixed with other materials.</p>

<p>3-(3-Methylphenoxy)propanoic acid (3MPPA) is a phenol with a 3-methyl group substituted for the hydroxyl group. It is a crystalline solid that melts at 96°C and decomposes when heated to 130°C. 3MPPA is a substrate for the enzyme catechol O-methyltransferase, which converts it to 3-O-methyldopa. This reaction occurs in both viable and nonviable cells. The kinetics of this reaction has been studied in detail and it has been shown that 3MPPA preferentially reacts with the active site of catechol O-methyltransferase.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2',3'-Dimethylphenyl)propionic acid is a prostaglandin compound that inhibits the production of vasoconstricting and vasodilating substances. It belongs to the class of amide, benzoic acid, and azacyclic compounds. The structural formula is CHCOOH. 3-(2',3'-Dimethylphenyl)propionic acid inhibits the response of cells to agonists such as histamine, serotonin, and bradykinin by binding to specific receptors on cell surfaces called integrins. This compound has been shown to have vasospastic effects in patients with Raynaud's phenomenon or other diseases involving vasospasm. 3-(2',3'-Dimethylphenyl)propionic acid also has thrombotic effects due to its inhibition of blood coagulation factors IIa and Xa.</p>

<p>3-(2,5-Dimethylphenyl)propionic acid is a cytotoxic agent that belongs to the group of carboxamides. It is lipophilic and has been shown to be effective against colon tumor cells in vivo. 3-(2,5-Dimethylphenyl)propionic acid binds to DNA chains and inhibits cellular proliferation by inhibiting the synthesis of nucleic acids. This agent also inhibits the activity of topoisomerases I and II, which are enzymes that are necessary for DNA replication and transcription. 3-(2,5-Dimethylphenyl)propionic acid has been shown to have a high cytotoxic potency in vitro but low potency against cultured human cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Bromopyridine-2-carboxamide is a dibenzazepine and an azacycle. It is used to study its affinity for the dopamine receptors, sodium channels, and histamine receptors. 6-Bromopyridine-2-carboxamide has been shown to block histamine receptors in the rat brain. This drug also has affinity for sodium channels and blocks them at lower concentrations than other drugs. Functional assays have demonstrated that 6-bromopyridine-2-carboxamide is a functional blocker of the ion channel receptor in human erythrocytes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Bis[(6-methylpyridin-2-yl)methyl]amine is a monoxide that is used as an electrocatalyst for the reduction of nitrite to nitric oxide. Bis[(6-methylpyridin-2-yl)methyl]amine is able to catalyze the conversion of an electron from a proton donor to a sulfide substrate, which generates a geometrical change in the molecule. The bis[(6-methylpyridin-2-yl)methyl]amine molecule has acidic properties and can be used in coordination chemistry as it can coordinate with gold electrodes. This compound also has been shown to have nitrite reductase activity, which may be due to its ability to reduce molecular oxygen.</p>

<p>Versatile small molecule scaffold</p>

<p>Pyrazolo[1,5-a]pyridine-3-carbonitrile is a crystalline solid in the form of an amorphous or polymorph. It has been shown to inhibit the kinase activity of protein tyrosine phosphatases and may be useful for the treatment of gastrointestinal disorders. The compound has also been shown to have antioxidant properties, which may be related to its ability to inhibit oxidative phosphorylation by inhibiting the mitochondrial membrane potential. Pyrazolo[1,5-a]pyridine-3-carbonitrile has also been shown to suppress proliferation and induce apoptosis in some types of cancer cells. This compound can serve as a nitrogen source for microbial growth and can inhibit bacterial growth by acting as an inhibitor of indolizine synthesis or nitrogen fixation.</p>

<p>4-Bromo-1,2-thiazol-3-ol is a palladium acetate catalyst that is used in the palladium-catalyzed synthesis of isothiazoles. It reacts with olefins to form (4-bromo)isothiazoles. 4-Bromo-1,2-thiazol-3-ol has been found to be effective for the synthesis of different types of isothiazoles.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dichlorophthalic acid is a divalent organic acid that is used as an intermediate in the production of other chemicals. 3,5-Dichlorophthalic acid is used as a regulator of plant growth and development. It can also be used to make different n-substituted compounds, such as naphthalene, phthalic anhydride, and 2,6-dichloro-pyridine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzyl-2-(bromomethyl)aziridine is a nucleophile that can be used as an intermediate in the synthesis of epoxides. It is used as a reactant in the formation of chiral epoxides, which are important for pharmaceuticals and agrochemicals. The addition of aziridines to activated esters provides the corresponding carboxylic acid. The reaction proceeds stereoselectively with 1-benzyl-2-(bromomethyl)aziridine, but not with other diamino compounds such as 1-benzyl-2-(chloromethyl)aziridine or 2-(bromomethyl)azetidine. Bromine is used to activate the carboxylic acid, which leads to a more reactive intermediate than other nonactivated forms.</p>

<p>Methyl cyclohex-2-enecarboxylate (MCHC) is a volatile compound that is found in actinomycetes and has been identified as the second major product of phenolic metabolism. MCHC is produced by the addition of an enolizable acetyl group to 2-cyclohexene-1-carboxylic acid. It can also be synthesized by the oxidation of cyclohexenyl alcohol, which is one of its main precursors. MCHC is a short-chain volatile compound that can exist as cis or trans isomers and has a boiling point of 136°C. The biosynthesis of MCHC occurs through a series of reactions that are difficult to identify because they have not yet been fully elucidated.<br>MCHC has been shown to cause cancer in animals, but it does not exhibit carcinogenic properties in humans because it does not bind well to DNA. The aromatic hydrocarbon content</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-isopropylpyrazin-2-ol is a volatile and catalytic compound that is used in the synthesis of methylated flavonols such as quercetin. It is a hydroxypyrazine that can be synthesized from the amino acid isobutylamine. 3-isopropylpyrazin-2-ol has been shown to inhibit o-methyltransferases and flavonol quercetin biosynthesis in tissues, and can be used for the production of other derivatives. This compound has also been shown to inhibit e coli growth, which may be due to its ability to inhibit enzymes involved in bacterial DNA replication.</p>

<p>1-(3-Nitrophenyl)-1H-pyrazole is a small molecule inhibitor of p38 kinase. It can be used to treat arthritis and other diseases that are caused by the overactivation of p38 kinase. 1-(3-Nitrophenyl)-1H-pyrazole also has the potential to be used as a combinatorial library for the discovery of new inhibitors for protein kinases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Amino-3,5,6-trifluorobenzene-1,2-dicarbonitrile (4AF) is a chemical compound that has been found to have antimicrobial properties. 4AF inhibits the growth of bacteria by hydrolyzing into 3,5,6-trifluoroaniline and trifluoroacetic acid. It also binds to polyamide and prevents the formation of bacterial cell walls. This process stops the synthesis of DNA and protein in the bacterial cell.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chlorophenylmethanethiol (3CPMS) is a delocalized molecule with a planar conformation. It has a resonance structure and can be found in the crystal structure of benzene. The hybridization of 3CPMS is sp2, which means that it is planar and has two electron pairs on each carbon atom. 3CPMS has the ability to form bonds with other molecules through hydrogen bonding or through the formation of covalent bonds with other molecules.</p>