Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,2-Dimethylchromane-6-carbaldehyde is a flavonoid compound that is structurally similar to abyssinone and resacetophenone. It has been shown to have anti-oxidant activity in the presence of hydrogen peroxide in vitro. 2,2-Dimethylchromane-6-carbaldehyde has also been shown to inhibit the growth of MCF7 cells by inducing apoptosis and cell cycle arrest at G0/G1 phase.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(3,4-Diethoxyphenyl)ethanamine is a quinazolone derivative that is electron deficient. It has been shown to inhibit the contractility of isolated rat ileum and guinea pig vas deferens preparations. 2-(3,4-Diethoxyphenyl)ethanamine also potently inhibits phosphorylation of myosin light chain and can be used as a tool for studying the involvement of phosphorylation in muscle contraction. It has been shown to inhibit lipid droplet formation in L6 cells by activating AMP-activated protein kinase (AMPK).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Propan-2-yl (2S)-2-amino-3-methylbutanoate is an amino acid derivative that is used as a chiral auxiliary. The compound has been used in the synthesis of amides, esters, and other amine products. It has also been used in the preparation of enantiomerically pure protonated amines. Propan-2-yl (2S)-2-amino-3-methylbutanoate can be used as a chiral auxiliary in chromatographic techniques to separate racemic mixtures into their enantiomers. This compound is mesomorphic at low temperatures and becomes isotropic at higher temperatures. Propan-2-yl (2S)-2-amino-3-methylbutanoate is also soluble in solvents with different polarities, such as water and chloroform, and has a molecular weight of 158.25 g/mol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-2-cyclohexen-1-ol is an organic compound that belongs to the group of chlorides, iodides, and yields. Mechanistic studies have shown that this compound reacts by nucleophilic attack at a reactive site that contains halides. The chloride ion is a terminal alkyne and has been shown to be reactive with 2-bromo-2-cyclohexen-1-ol. The indole nitrogen in 2-bromo-2-cyclohexenol has been shown to undergo nucleophilic substitution with an aryl chloride substrate. This reaction has been shown to be reversible by adding base.</p>

<p>Versatile small molecule scaffold</p>

<p>Prop-2-en-1-yl benzoic acid is an alkenoic, organometallic compound that is a metabolite of 2-bromopropane. It can be obtained from the bromolactonization of tetrahydrofuran with lithium aluminum hydride followed by allylic oxidation with chromium oxide and sodium hydroxide. Prop-2-en-1-yl benzoic acid has been shown to inhibit the enzyme acetylcholinesterase, which leads to increased levels of acetylcholine in the brain. This leads to increased activity on nicotinic receptors and improved cognition. This compound has also been shown to be a ligand for donepezil, which is an inhibitor of cholinesterases. Donepezil is used as a treatment for Alzheimer's disease and other forms of dementia, but it does not cross the blood brain barrier. In this case, prop-2-en-1</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile is an analogue of diazocine. It has a dihedral angle of 12.3° and a benzene ring.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Benzyloxy)-2-hydroxybenzaldehyde is an enamine that is used in the synthesis of benzofuran derivatives. This compound can be synthesized by a sequence of reactions that starts with the condensation of benzaldehyde and 2-hydroxyacetophenone. The lactaldehyde formed in this reaction is then converted to the desired product by treatment with sodium methoxide. 3-(Benzyloxy)-2-hydroxybenzaldehyde may also be used for the asymmetric synthesis of benzoquinones, imines, and other heterocycles.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>